Faculty Of Physical Therapy Research Paper
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Item Comparative Response of Oxidative Stress to Baduanjin Exercise Versus Electro-Acupuncture in Patients with Type 2 Diabetes Mellitus(Horizon Research Publishing, 2025-05-14) Ali Mohamed Ali Ismail; Mona Mohamed Morsy; Orchid Saber AbdelFadil Saber; Ahmed Mohamed Abdelhalim Elfahl; Asmaa Mohamed Ahmed; Sami Kamal Mohamed Elgendy; Alyaa Abdallah Atallah Ahmed Zaid; Amera S. Aly Yousef; Asmaa M. Al-EmranyObjective: Oxidative stress is aggravated by the existence of type 2 diabetes mellitus. Baduanjin exercise and acupuncture are two traditional Chinese treatment methods that are commonly used to treat diabetes and its complications. This study aimed to compare the oxidative stress response to a 12-week electro-acupuncture versus Baduanjin exercise in patients with type 2 diabetes mellitus. Material and Methods: Sixty non-obese patients with type 2 diabetes mellitus were assigned randomly to the EA group (n=30) or Baduanjin-exercise group (n=30). EA group received a 2-Hz electro-stimulation to needles inserted in bilateral PC4 and PC6 acupoints for 40 minutes while the other group received Baduanjin exercise for 40 minutes. The 12-week treatment was performed daily (except Friday) in both groups. Besides the measurement of serum lipid hydro-peroxidase (as an oxidative stress marker), serum antioxidants such as superoxide dismutase and nitric oxide were assessed before and after 12 weeks. Results: Both EA and Baduanjin exercise produced a highly significant decrease in serum lipid hydro-peroxidase and an increase in serum superoxide dismutase and serum nitric oxide levels. Comparison of post-treatment lipid hydro-peroxidase, superoxide dismutase, and nitric oxide between Baduanjin exercise and electro-acupuncture groups did not show a significant difference. Conclusions: Both Baduanjin exercise and electro-acupuncture are good anti-oxidative therapeutic modalities to lower oxidative stress in patients with type 2 diabetes mellitus.Item Effects of diaphragmatic breathing exercise on sleeping quality, cortisol, cardiovascular autonomic functions, depression, and fatigue: a randomized-controlled trial in women with systemic sclerosis(Termedia Publishing House Ltd, 2025-04-30) Ali Mohamed Ali Ismail; Nadia Saad Sayed Ahmed El Gressy; Mona Darwish Hegazy; Omnia Saeed Mahmoud Ahmed; Ahmed Mohamed Abdel-Halim ElfahlIntroduction: The available pharmacotherapies (immunosuppressant therapies) for systemic sclerosis (SSc) are not curative, especially in cases with non-lethal but challenging manifestations or complications of the disease. Fatigue, anxiety, depression, an over-activated hypothalamic–pituitary– adrenal axis (stress axis), and low sleeping quality are the common SSc-induced non-lethal manifestations that need close management. Diaphragmatic breathing tele-exercise (DBTE), as a standalone deep breathing retraining and tele-interventional technique, has not been utilized in the rehabilitation context of non-lethal complications in women with SSc. This online interventional study aimed to explore the efficacy of DBTE in controlling depression, cardiovascular autonomic functions, stress, sleep, and anxiety in women with SSc. Material and methods: This randomized controlled tele-interventional trial recruited 40 non-obese women with SSc (aged > 18 years old) from an Egyptian teaching hospital. Women were randomly assigned to the DBTE group (n = 20) or non-DBTE group (n = 20). The DBTE group underwent 12-week 20-minute morning and evening DBTE sessions (sessions were supervised daily through the Zoom video conference program). The non-DBTE group served as a waitlist control group. The outcomes of this study were diastolic blood pressure (BPD), serum cortisol, the total score of the Hamilton Anxiety Rating Scale (HARS-TS), systolic blood pressure (BPS), the general score of the Pittsburgh Sleep Quality Index (PSQI-GS), pulse rate (PR), the eight-item Patient Health Questionnaire (EI-PHQ8 ), respiratory rate (RR), and the Visual Analogue Scale of fatigue (VAS-F). Results: In the DBTE group, there were significantly lowered values of PSQI-GS, HARS-TS, EI-PHQ8, serum cortisol, VAS-F, and cardiovascular/respiratory autonomic functions (BPS, BPD, RR, and PR). In the non-DBTE group, no significant changes were observed for any variables. Conclusions: It can be concluded from this tele-interventional trial that the 12-week application of DBTE may reduce cortisol, EI-PHQ8 , PSQI-GS, HARS-TS, BPS, BPD, RR, PR, and VAS-F in women with SSc.Item THE IMPACT OF ELECTROMAGNETIC THERAPY ON PAIN AND HEMODYNAMICS IN PERIPHERAL ARTERIAL DISEASE(NII KPSSZ, 2025-05-09) Omnia Saeed Mahmoud Ahmed; Amir Al Araby Abou Tahoun; Alshaimaa Alsayed Ali; Mahmoud Nabawy Mahmoud Khattab; Hagar Ahmed El-HadidyAim. Despite the improvement with rest, lower-limb intermittent claudication is a bothersome issue/symptom in patients with peripheral arterial disease (PAD). Utilizing its benefits in increasing vasodilation/angiogenesis in patients with circulatory disorders/issues, adding pulsed electromagnetic therapeutic modality (PEMTM) to exercise rehabilitation of PAD is a newly recommended intervention in managing PAD-induced lower-limb intermittent claudication. This interventional study aimed to check the effects of adding PEMTM to elliptical exercise on vascular hemodynamics, functional outcomes, and quality of life in PAD sufferers. Methods. PAD older men were assigned randomly into the group of elliptical exercise (n = 20, received only elliptical exercise and by-physician prescribed for-PAD pharmacotherapies) or study group (n = 20, received PEMTM, elliptical exercise, and by-physician prescribed for-PAD pharmacotherapies). The eight-week PEMTM or elliptical exercise was applied 3 times weekly. The following outcomes were evaluated: PAD patients’ ankle brachial index test, diameter of posterior tibial artery, lower-limb claudication pain time, lower-limb claudication pain distance, modified walking-impairment questionnaire, short-form-36 health survey, disease-specific quality-of-life evaluation by the intermittent claudication questionnaire, summation score of short physical performance battery, pain-free six-minute walked distance, and the total six-minute walked distance. Results. The present paper showed a significant effect of elliptical exercise alone or combined with PEMTM on all measured parameters with a significant superiority to the combined application of elliptical exercise and PEMTM. Conclusion. Gained hemodynamic and functional benefits of elliptical exercise in PAD elderly could be magnified by adding PEMTM to elliptical exercise.Item Effect of training using the Biodex system on dynamic balance and physical performance: a randomized controlled balance--training trial in hemodialysis patients with osteopenia(Wydawnictwo Continuo, 2025-03-26) Hagar Ahmed El-Hadidy; Marwa Abdelfattah Gaballah; Sally Mohamed Abouelfetouh; Rania Hakim Hamed; Sara S. El-Din; Omnia Saeed Mahmoud AhmedBackground. The Biodex Balance Training System (BBTS) has been utilized as an imbalance assessment/treatment tool in various populations and diseases. Objectives. The aim of this study was to investigate the effect of BBTS on dynamic balance and physical performance in hemodialysis (HD) patients with osteopenia. Material and methods. 58 women with HD and osteopenia were randomly assigned to a 12-week Biodex-training group (BTG, n = 29) or a non-trained group (n = 29). The training, 3 times per week, was conducted using BBTS and lasted for 10 minutes, with the two types of training – weight shift and postural stability – each lasting 5 minutes, allowing the HD patients to relax for 2 minutes between each type of exercise. HD patients’ femoral bone mineral density (T-score) was assessed in both groups. Dynamic balance was assessed in both groups via the HD participants’ BBTS-extracted overall stability index (OASI), BBTS-extracted anteroposterior stability index (APSI), and BBTS-extracted mediolateral stability index (MLSI). The HD patients’ physical performance was also evaluated using a 6-minute walking distance (6MWD) test and total scored points of a 3-component Short Physical Performance Battery (SPPB) test. Results. After using BBTS in a balance-training program, significant improvements in HD participants’ OASI, APSI, T-score, MLSI, SPPB, and 6MWT were recorded in the BTG, while all outcomes of the NTG did not show the same results. Conclusions. It can be concluded that utilizing BBTS in a 12-week balance-training program improves participants’ OASI, APSI, T-score, MLSI, SPPB, and 6MWT in HD patients with osteopenia.Item The Effect of Laser Biostimulation at Sensitized Acupoints on Chronic Pelvic Pain and Quality of Life in Women with Pelvic Inflammatory Disease: A Randomized Controlled Trial(Multidisciplinary Digital Publishing Institute (MDPI), 2025-02-18) Marwa Esmael Hasanin; Sobhy Mahmoud Aly; Mona Mohamed Taha; Lama Saad El-Din Mahmoud; Monira I. AldhahiBackground and Objectives: Chronic pelvic pain (CPP) is a common complication of pelvic inflammatory disease (PID). Although acupuncture has been increasingly used for the management of CPP, there is insufficient research to support the use of laser stimulation of sensitized acupoints. This study aimed to investigate the effects of laser on sensitized acupoints on pelvic pain perception and quality of life in women with pelvic inflammatory disease. Materials and Methods: Thirty-six women with CPP caused by chronic pelvic inflammatory disease were randomly divided into two equal groups. Both groups received non-steroidal anti-inflammatory drugs, while the study group also received a low-level laser at sensitized acupoints for 6 weeks. All the patients were evaluated before and after the intervention. The 12-item Short-Form Health Survey (SF-12) was used to measure the quality of life, while a pressure algometer and visual analog scale for pain (VAS-P) were used to measure pain sensitivity and intensity, respectively. A mixed MANOVA was used to investigate the effects of the treatment. Results: A mixed MANOVA on VAS, SF-12, and PPT scores revealed significant interaction effects of treatment and time (F = 38.34, p = 0.001, partial η 2 = 0.96) and main effects of treatment (F = 9.74, p = 0.001) and time (F = 110.1, p = 0.001). Post-treatment, the study group showed greater reductions in VAS (MD = −1.00, p = 0.001), improvements in SF-12 (MD = 9.11, p = 0.001), and increased Pressure Pain Thresholds (PPT) at multiple anatomical points (p = 0.001–0.01). Conclusions: Laser biostimulation of neurogenic-sensitized acupoints significantly improves pain perception, intensity, and quality of life in women with CPP. suggested that the utilization of laser therapy at sensitized acupoints should be considered a potential component of a rehabilitation program for females suffering from chronic pelvic pain resulting from pelvic inflammatory disease. (Clinicaltrials.gov identifier: NCT05537207; Date of registration: 13 September 2022).Item Impact of Temperature Variations on the Viability and Infectivity of Sporulated Eimeria papillata Oocysts in C57BL/6 Mice(Springer New York, 2025-03-12) Mohammed Albeshr; Rewaida Abdel‑Gaber; Nagham Dkhil; Manal F. Elkhadragy; Esam M. Al‑Shaebi; Saleh Al‑QuraishyEimeria is a protozoan apicomplexan parasite that afects animals and poultries. This study investigated how temperature variations impact the inactivation of sporulated E. papillata oocysts during experimental infections in mice. A total of 20 male C57BL/6 mice were divided into four groups, with fve mice in each group, as follows: Group 1: Control group – Group 2: Infected group inoculated with fresh oocysts (subjected to 23 ℃ for 7 days) – Group 3: Infected group inoculated with thermal oocysts (subjected to heating conditions at 100 ℃ for 60 min) – Group 4: Infected group inoculated with frozen oocysts (subjected to freezing at −20 ℃ for 7 days). An oral infection was initiated using 103 sporulated E. papillata oocysts to inoculate groups 2–4. Biological indicators, including body weight (BW) and feed intake (FI), were evaluated for each group. Oocyst output was assessed on day 5 post-infection. After sacrifcing the mice, jejunal tissues were collected and processed for histopathological and biochemical analyses. Our fndings indicated signifcant morphological alterations of sporulated Eimeria oocysts (i.e. a reduction in oocyst size and rounded shape of sporozoite) after being subjected to heating and freezing conditions. During the in vivo study, temperature treatment data shows signifcant inactivation of oocysts, with no fecal shedding. This result refects enhancements in biological indicators and histopathological injuries, with the absence of intracellular Eimeria stages in the jejunal tissues, alongside a restoration of nutrient composition, particularly carbohydrates and proteins. Signifcant observations were also recorded regarding catalase (CAT), glutathione (GSH), nitric oxide (NO), and hydrogen peroxide (H2O2) levels. Temperature changes impact the viability of Eimeria oocysts and their role in coccidiosis. More research is needed on other biotic and abiotic factors in managing the disease.Item Non-coding RNAs: emerging biomarkers and therapeutic targets in cancer and inflammatory diseases(Frontiers Media SA, 2025-03-10) Basma Hossam Abdelmonem; Lereen T. Kamal; Lilian Waheed Wardy; Manon Ragheb; Mireille M. Hanna; Mohamed Elsharkawy; Anwar AbdelnaserNon-coding RNAs (ncRNAs) have a significant role in gene regulation, especially in cancer and inflammatory diseases. ncRNAs, such as microRNA, long non-coding RNAs, and circular RNAs, alter the transcriptional, post-transcriptional, and epigenetic gene expression levels. These molecules act as biomarkers and possible therapeutic targets because aberrant ncRNA expression has been directly connected to tumor progression, metastasis, and response to therapy in cancer research. ncRNAs’ interactions with multiple cellular pathways, including MAPK, Wnt, and PI3K/AKT/mTOR, impact cellular processes like proliferation, apoptosis, and immune responses. The potential of RNA-based therapeutics, such as antimicroRNA and microRNA mimics, to restore normal gene expression is being actively studied. Additionally, the tissue-specific expression patterns of ncRNAs offer unique opportunities for targeted therapy. Specificity, stability, and immune responses are obstacles to the therapeutic use of ncRNAs; however, novel strategies, such as modified oligonucleotides and targeted delivery systems, are being developed. ncRNA profiling may result in more individualized and successful treatments as precision medicine advances, improving patient outcomes and creating early diagnosis and monitoring opportunities. The current review aims to investigate the roles of ncRNAs as potential biomarkers and therapeutic targets in cancer and inflammatory diseases, focusing on their mechanisms in gene regulation and their implications for non-invasive diagnostics and targeted therapies. A comprehensive literature review was conducted using PubMed and Google Scholar, focusing on research published between 2014 and 2025. Studies were selected based on rigorous inclusion criteria, including peer-reviewed status and relevance to ncRNA roles in cancer and inflammatory diseases. Non-English, nonpeer-reviewed, and inconclusive studies were excluded. This approach ensures that the findings presented are based on high-quality and relevant sourcesItem High-intensity laser therapy can improve pain, health status and quality of life in women with fibromyalgia: a single blindedrandomized controlled trial(Springer Verlag, 2025-03-04) Kerolous Ishak Shehata Kelini; Marwa Shafiek Mustafa Saleh; Menna Allah Mohammed Abbas; Mohamed Bayoumi Ibrahim Bayoumi; Sara M. AhmedThis study was conducted to explore the influence of High-Intensity Laser Therapy (HILT) on health status, pain intensity, Pain Pressure Threshold (PPT), and Quality of Life (QoL) in Fibromyalgia (FM) women. Fifty-two women with FM were randomly divided into either the HILT group (n=26) or the control group (n=26). Those in the HILT group underwent HILT alongside an exercise program consisted of low-impact aerobics training and stretching exercises, while the control group received the exercise program only. Treatments were administered three times per week for six weeks. Fibromyalgia symptoms and health status (Revised Fibromyalgia Impact Questionnaire (RFIQ), Pain intensity (visual analog scale), PPT (pressure algometer), and QoL (Short Form 36 Questionnaire) were measured pre and post six-week intervention timeframe. Regarding baseline data, insignificant differences were identified between groups (p>0.05). Comparing groups after 6-week intervention reveals statistically significant differences in favor of the HILT group across all measured aspects (p<0.001). HILT may be an effective treatment for women with FM, potentially enhancing pain management, reducing the impact of FM, and improving their QoL.Item Inspiratory Muscle Trainer Versus Diaphragmatic Breathing Exercise on 6-Minute Walk Test in Adolescent Girls with End-Stage Renal Disease(Prince of Songkla University, 2025-02-07) Donia M. Elmasry; Manal A. El-Shafei; Shimaa Abd EL-Rahim Abd EL-Aty; Omnia Saeed Mahmoud AhmedObjective: Inspiratory muscle weakness (IMW) is very common among adolescents with end-stage renal disease (ESRD). Untreated IMW in ESRD adolescents induces acute and chronic pulmonary complications, low physical performance, and impairment in quality of life (QoL). This was a 12-week breathing-retraining trial that compared the effects of threshold inspiratory muscle trainer (TIMT) versus the diaphragmatic breathing exercise procedure (DBEP), on ESRD adolescent girls’ maximal inspiratory pressure (MIP) and QoL, which was assessed by the Child Health Questionnaire (50-item parent form) (CHQ/PF50), pulmonary functions, and six-minute walk test (6MWT). Material and Methods: This breathing-retraining trial enrolled forty adolescent girls with ESRD. The girls were randomly divided into two groups: one group contained twenty girls that were trained by TIMT, while the other group contained 20 girls whom were trained by DBEP. The 20-minute rehabilitation of IMW by TIMT or DBEP was applied 3 times weekly. Adolescent girls’ forced vital capacity (FVC), CHQ/PF50-related score of physical summary, MIP, 6MWT, CHQ/PF50-related score of psychosocial summary, forced expiratory volume in the first second of girls’ expiration (FEV1), and 6MWT-associated physiological data (blood pressure, heart rate, and rate of perceived exertion) were assessed. Results: All outcomes of adolescent girls with ESRD in the first group that were trained by TIMT showed significant improvements, whereas the other group’s girls did not show the same reported significant improvements. Conclusion: Compared to DBEP, the 12-week training by TIMT significantly improved ESRD adolescent girls’ FVC, CHQ/PF50-related score of physical summary, MIP, 6MWT, CHQ/PF50-related score of psychosocial summary, FEV1, and 6MWT-associated physiological data.Item Influence of pelvic position on shoulder range of motion(BioMed Central Ltd, 2025-01-17) Bishoy S. Lobbos; Mohamed M. M. Essa; Alaaeldin Khaireldin; Mohamed Y. Gamal El-Din; Phillips Rizkallah; Heba Allah SamyBackground pelvis and shoulder are deeply integrated. They are connected by myofascial slings. The pelvic and spinal posture affects the position of the scapula and the activity of its muscles and affects acromio-humeral distance and so that affects shoulder movement. The aim of the study was to investigate the influence of pelvic position on the shoulder range of motion. Methods The full active range of motion (flexion/extension, abduction, and external/internal rotation) of both shoulders was measured by digital goniometer for 33 normal adult subjects. Measurements were taken from a standing position in the following pelvic positions: 1- Neutral posture, 2- Evoked anterior and posterior pelvic tilt, 3- Evoked right and left pelvic rotation, 4- Evoked right and left lateral pelvic tilt. For every shoulder movement, One-Way ANOVA including Tukey post hoc test was used to compare between different positions. Results Anterior pelvic tilt leads to a significant increase in flexion and a significant decrease in extension of both shoulders (P value was <0.001). Posterior pelvic tilt leads to the opposite. Pelvic rotation leads to a significant decrease in shoulder flexion on the same side of rotation and shoulder extension on the opposite side of rotation (P value was <0.001). Lateral pelvic tilt leads to a significant decrease in abduction on the same side of lateral tilt (P value was <0.001).Item From contamination to detection: The growing threat of heavy metals(Elsevier B.V, 2025-01-05) Basma Hossam Abdelmonem; Lereen T. Kamal; Rana M. Elbaz; Mohamed R. Khalifa; Anwar AbdelnaserHeavy metals like lead, mercury, cadmium, and arsenic are environmental pollutants that accumulate in ecosystems and pose significant health risks to humans and wildlife, primarily through food chain contamination where plants absorb heavy metals, affecting their growth and threatening consumer health. Cognitive and cardiovascular functions are particularly affected by exposure to heavy metals even at low concentrations through the induction of oxidative stress. Various analytical techniques are used in measuring heavy metals in different environmental and biological samples. The atomic absorption spectroscopy (AAS) offers low cost, simplicity, and portability but lacks sensitivity for certain metals. Although more sensitive, the high cost of inductively coupled plasma mass spectrometry (ICP-MS) may limit laboratory accessibility. The inductively coupled plasma with atomic emission spectrometry (ICP-AES) is known for its broad dynamic linear range and ability to identify minute variations in concentration. Atomic fluorescence spectrometry (AFS) is considered a powerful tool for quantifying heavy metals due to its high sensitivity, low detection limits, and wide linear range. The current article reviews heavy metal pollution’s impact on health and spectrometric techniques for the detection of these contaminants. This may help efforts of international, and regional policies towards preventing this health hazard problem.Item Effectiveness of McKenzie exercises plus stabilization exercises versus McKenzie exercises alone on disability, pain, and range of motion in patients with nonspecific chronic neck pain: A randomized clinical trial(IOS Press BV, 2024-11-08) Doaa I . Amin; Ghada I . Mohamed; Mohamed M. ElMeligieBACKGROUND: Chronic nonspecific neck pain is a common disorder that causes disability and reduced quality of life. Effective conservative treatment options are needed to manage this condition. OBJECTIVE: This randomized trial compared the efficacy of McKenzie exercises alone versus McKenzie plus cervical and scapulothoracic stabilization training for patients with chronic nonspecific neck pain. METHODS: A randomized controlled trial was conducted in an outpatient physical therapy clinic. 76 patients with chronic (> 3 months) neck pain were randomized to 6 weeks of either McKenzie exercises alone (n= 38) or McKenzie plus stabilization exercise (n= 38). The McKenzie protocol included posture correction, range of motion exercises, and lateral neck stretches. The stabilization program added targeted exercises for the neck and scapula. RESULTS: The combination of McKenzie plus stabilization exercises resulted in significantly greater reduction in current neck pain intensity compared to McKenzie alone at 6 weeks (mean difference: -1.2 points on 0-10 scale, 95% CI -1.8 to -0.6; p< 0.001). Neck disability improved in both groups. Cervical range of motion also improved more with the addition of stabilization, except for extension. CONCLUSION: Adding specific cervical and scapulothoracic stabilization exercises to a standard McKenzie protocol led to clinically meaningful reductions in neck pain compared to McKenzie therapy alone in patients with chronic nonspecific neck pain. This combined approach can improve outcomes.Item Burnout among Egyptian physical therapists in burn departments(DJ Studio, 2024-11-03) Mohamed Bayoumi Ibrahim Bayoumi; Ahmed Mohamed Nagy; Saher Lotfy El Gayar; Shaimaa Mohamed Metawee; Nehad Mohamed AbdElnabi Mousa; Heba Mohamed MohamadyBackground. Burnout is a common syndrome among healthcare providers which affects their quality of life and the healthcare service they provide. Physical therapists in burn units are at high risk to develop burnout due to several stressors. Objective. This study's main objective was to evaluate the extent of burnout experienced by physical therapists employed in burn units. Design. The present study employed a cross-sectional study. Methods. A total of 520 physical therapists, aged 24–44 years, working in burn units of Egyptian hospitals participated in our study. Burnout evaluation was conducted using the Maslach Burnout Inventory Human Services Survey (MBI-HSS). Results. 520 physical therapists participated in the study, about 50% of them were aged between 30 and 40 years, and about 44.9% had a bachelor's degree. Females represented 63.3% of them. According to the results of the MBI-HSS assessment, it was found that 73.5% of the participants exhibited symptoms of burnout on the emotional exhaustion (EE) scale, while 44% displayed burnout on the depersonalization (DP) scale. Additionally, 51% of the participants reported low personal accomplishment (PA) on the scale measuring this construct. Results confirmed that men, more than women, experienced depersonalization, and they were less satisfied with their professional accomplishments. Conclusion. Physical therapists working in burn units who responded to the survey expressed severe burnout. To assess the impact of burnout on physical therapists working in burn units and to create strategies to lessen it, more study is needed.Item Effect of electromagnetic stimulation combined with visceral manipulation on stress urinary incontinence in postmenopausal women: A randomized controlled trial(Churchill Livingstone, 2024-10-18) Dina M.A. Mohamed; Dalia M. Kamel; Alaa M. El-Moatasem; Ebtesam A. Ali; Marwa A. Radwan; Sara M. AhmedObjectives: The aim of the study is to determine how electromagnetic stimulation and visceral manipulation can improve pelvic floor strength and reduce the severity of symptoms of postmenopausal stress urinary incontinence (SUI). Methods: This randomized controlled trial was conducted on 50 postmenopausal female participants aged 50–66 years with a body mass index (BMI) ≥ 30 kg/m2. Participants were equally randomized into the study (A) and control (B) groups. The study group (A) underwent 36 pulsed electromagnetic stimulation (PEMS) sessions (20 min/session; 3 sessions a week/12 weeks), 12 sessions of visceral manipulation therapy (VMT) maneuvers (once weekly/weeks), and 24 supervised pelvic floor muscle training (PFMT) sessions (45–60 min/session; twice weekly/12 weeks), along with general advice. For 12 weeks, the control group (B) received the same PFMT and general advice. Kegel perineometer was used to measure vaginal squeeze pressure (VSP) and the urogenital distress inventory questionnaire-short form (UDI-6) to assess the severity of urinary incontinence (UI) symptoms in both groups before and after the treatment. Results: The results revealed statistically significant improvements (p < 0.05) in both VSP and UDI-6 scores in group A compared to group B. Conclusion: Electromagnetic stimulation combined with visceral manipulation and supervised PFMT is more efficient than PFMT alone on SUI in postmenopausal women. Therefore, it is advisable to incorporate this combined approach into pelvic floor rehabilitation programs.Item Effect of High-Intensity Laser Therapy on Carpal Tunnel Syndrome Patients: A Systematic Review and Meta-analysis(Lippincott Williams and Wilkins Ltd., 2024-11-11) Mohamed M. ElMeligie; Mahmoud M. Ismail; Yasmine S. Gomaa; Amr M. Yehia; Hend R. Sakr; Omnia M. ElGendyObjective: To provide a strong foundation for the use of high-intensity laser therapy in carpel tunnel syndrome, we conducted a systematic review and meta-analysis to investigate the outcomes of short- and long-term follow-up studies. Design: This is a systematic review and meta-analysis. Results: Sample sizes of included studies ranged from 16 to 98 patients (N = 308). Overall, a significant difference between the treatment and control groups were found across majority of the measures. Studies using a 4-wk follow-up period, however, only found significantly greater benefits for high-intensity laser therapy in visual analog scale compared with placebo (P = 0.0191), transcutaneous electrical nerve stimulation (P = 0.0026), and low-intensity laser therapy 20 J/cm(2) (P < 0.0002), and exercise (P < 0.0001). For improvement in visual analog scale score over a long treatment period, high-intensity laser therapy was also preferred over control group (P < 0.0071). Insufficient evidence exists to determine effect of high-intensity laser therapy on nerve conduction examinations. The only statistically significant differences observed in examinations were in relation to sensory nerve action potential (P = 0.0083) and sensory nerve conduction velocity (P = 0.0468). Conclusions: Moderate evidence exists regarding efficacy of high-intensity laser therapy compared with placebo, high-intensity laser therapy + wrist splint, and exercise in a short period of follow-up time but evidence on long-term follow-up is limited.Item Myofascial release; a diagnostic tool for kneeabdomen and knee myofascial pain syndromes in knee osteoarthritic patients. An interventional based prevalence study(DJ Studio, 2024) Olfat Diab Kandil; Hamed Mohammed Elkhozamy; Ibrahim Tobba Mohamed; Bassem Galal Eldein El Nahass,Background. Knee osteoarthritis (OA) is detected in all grades in imaging of asymptomatic individuals. Knee‑abdomen syndrome (KAS) and knee myofascial pain syndrome (KMPS) are newly identified syndromes of knee pain originating from myofascial induced stress upon knee’s capsule. Objective. To measure prevalence of KAS and KMPS among knee OA patients, and to explore concepts of the new syndromes. Methods. Intervention based prevalence study. Representative sample of 61 patients (pts) of knee OA underwent one session of Myofascial release (MFR). Pain was evaluated and averaged pre and immediately after MFR, during standing, active knee flexion and extension, and squat. Pain reduction of 50% is considered diagnostic for KMPS and KAS. Pain reduction maintained for one week is diagnostic for KAS. Results. KAS and KMPS are reconstructed as knee myofascial pain spectrum (KMPs). 13% of patients have KMPs and asymptomatic OA with 100% pain reduction after MFR. 20% of pts have symptomatic OA with no pain reduction. 67% have KMPs with more than 20% pain reduction. Conclusion. KMPs is identified in most knee OA patients. Asymptomatic knee OA is misdiagnosed as source of pain in one in every ten patients.Item Efficacy of mirror therapy in improving hand function post flexor tendon repair(Universidad de Murcia, 2024-04-15) Mohamed Bayoumi Ibrahim Bayoumi; Ahmed Mohamed Nagy Saleh; Karim Ibrahim Saafan; Shaimaa Mohamed Ahmed ElsayehThe aim of this study was to determine the efficacy of mirror therapy (MT) in improving the total active range of motion (AROM) of the affected finger, hand grip strength, and hand function in patients with flexor tendon repair (FTR) in zone II. The study was an open-label, parallel-group, randomized controlled trial. Thirty patients with zone II FTR, aged 20-45 years, were recruited and randomized into two equal groups: the MT group and the sham MT group. The intervention began in the fourth week post-operation, consisting of thirty minutes of MT or sham MT, three sessions per week for four weeks, in addition to the traditional physical therapy (PT) program. The total AROM of the interphalangeal (IP) joints of the affected fingers, hand grip strength, and hand function were assessed. After four weeks of intervention, the percentage change in total AROM was 25.7% in the MT group and 19.93% in the sham MT group. Additionally, hand grip strength and Michigan Hand Outcomes Questionnaire (MHQ) scores showed greater improvement in the MT group compared to the sham MT group (p < 0.05). Adding MT to the traditional PT program may be more effective than the traditional PT program alone in improving the AROM of the interphalangeal (IP) joints of the operated fingers, grip strength, and MHQ scores.Item Physical therapy in burn care: Development of clinical prediction rules to determine the efficacy of low-level laser therapy(Universidad de Murcia, 2024-09-11) Mohamed Bayoumi Ibrahim Bayoumi; Asmaa Fawzy El-Sayed Attalla; Shimaa Sayed Mahmoud; Salah Eldin Bassit Elsayed; Shimaa Mohamed Metawee; Ahmed Mohamed NagyThis study aimed to demonstrate the benefits of low-level laser therapy (LLLT) on burn healing and to investigate whether patients' age, burn wound size, wound stage, and total burned surface area influence the burn wound healing response to LLLT. This was a quasi-experimental study with a single-group design that included eighty male and female patients with partial-thickness burn wounds recruited from burn units. The participants were placed in a single intervention group receiving LLLT. The duration of the intervention was six weeks, divided into 18 sessions (three sessions per week). The statistical analysis was conducted using version 25 of the SPSS statistical package for Windows. The results showed a statistically significant negative relationship between wound improvement from LLLT and age (p < 0.05) and between total body surface area (TBSA) and wound improvement (p < 0.05). Additionally, a statistically significant positive relationship was found between initial wound size and wound improvement (p < 0.05). There was no statistically significant 3. Supplement 1. . relationship between wound improvement and wound stage (p > 0.05). The current study revealed that age, TBSA, and initial wound size can predict the efficacy of low-level laser treatment for burn wounds.Item Physical therapy in burn wound healing: Development of clinical prediction rules to identify the efficacy of pulsed electromagnetic therapy(Universidad de Murcia, 2024-04-15) Ahmed Mohamed Nagy; Shaimaa Mohamed Ahmed Elsayeh; Mohamed Bayoumi Ibrahim Bayoumi; Shimaa Mohamed Metawee; Omnia Saeed Mahmoud Ahmed; Karim Ibrahim SaafanMany studies have demonstrated the effect of pulsed electromagnetic therapy (PEMT) on wound healing. This study aimed to develop a clinical prediction rule (CPR) to assess PEMT's efficacy in burn healing, potentially enhancing treatment decisions and outcomes. It was a one-group intervention study with 46 patients (21 males, 25 females) aged 20 to 55 years, having partialthickness burns in the first or second healing stage, and a total burned surface area (TBSA) over 15%. The intervention involved pulsed electromagnetic therapy (Fisioline, Italy) for up to six weeks, with 60-minute sessions at 12 Hz and 12 Gauss, three times per week. The statistical analysis was conducted using the SPSS. The study revealed a significant decline in wound surface area (WSA) post-intervention (p < 0.05). A significant negative relationship was found between wound improvement and both age and total body surface area (TBSA) (p < 0.05), while a significant positive relationship was observed between wound improvement and initial wound size (p < 0.05). No significant relationship was found between wound improvement and wound stage (p > 0.05). The 3. Supplement 1. Article 33. study concluded that pulsed electromagnetic therapy significantly reduces wound surface area. Additionally, age, TBSA, and initial burn wound size are important predictors of the therapy's efficacy in treating burn wounds.Item Effect of adding telerehabilitation home program to pharmaceutical treatment on the symptoms and the quality of life in children with functional constipation: a randomized controlled trial(Springer Verlag, 2024-09) Soliman, Amir ; AboAli, Safy Eldin M; Abdel Karim, Amel E; Elsamahy, Sara A; Hasan, Judy ; Hassan, Badr Al‑Amir ; Mohammed, Amira HPainful defecation, the passage of hard stools, unpleasant or irregular bowel deviation/movements from regular rate, and/or the feeling of not enough elimination of stool are common symptoms of functional constipation. The goals in treating constipation are to produce soft, painless stools and to prevent the re-accumulation of feces. This study looked at how the telerehabilitation home program (TRP) affected the symptoms of FC and the children who were constipated in terms of their quality of life. A randomized controlled trial included 400 children aging 4–18 years with functional constipation distributed in two groups: control group consisted of 200 children receiving pharmaceutical treatment and the intervention group consisted of 200 children receiving the telerehabilitation home program in addition to pharmaceutical treatment. Both groups received the interventions for 6 months. The outcomes in terms of functional constipation symptoms and quality of life are measured and compared pre- and post-interventions. Adding the telerehabilitation home program to pharmaceutical treatment of functional constipation in children results in prominent improvement in the condition; there is a significant difference between the intervention and control group in all Rome criteria which assess symptoms of functional constipation except rush to the bath-room to poop which showed non-significant difference; there is also a significant difference between the intervention and control group in all domains of the SF-36 questionnaire which assess quality of life except the mental health domain which showed non-significant difference. Conclusion: Adding the telerehabilitation home program to pharmaceutical treatment of functional constipation in children results in prominent improvement in symptoms of functional constipation and quality of life. Trial registration: Our study was registered retrospectively with Clinicaltrials.gov under the identifier NCT06207721 on 5 January 2024. (Table presented.)