MSA Repository "MSAR"

MSAR University's Digital Repository is a documentation and digitization of all university outcomes that are of effective value in the scientific and academic community and reflects the university's image, work, and effective contribution to society Through MSAR Digital Repository, the university managed to collect, store, archive and publish digital content - including documents, audio files, images and data sets - all in a safe place. MSAR is one of the strongest University Digital Repositories in Egypt and documented in the DSPACE community with its latest versions.

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MSA Journals 140
A Full content for MSA university Faculties Journals
MSA Theses 5
A digital collection of MSA University postgraduate theses, including PhD and Master’s theses, organized by academic degree and faculty.
MSA University Academic Graduation Projects 1153
A Full content for msa university Distinguished Graduation Projects Yearbook
MSA University Academic Research 3720
MSA University Campus 2
Images for MSA University " sites - building - landscape "

Recent Submissions

Prolonged high-dose prenatal caffeine exposure induces organ-specific developmental toxicity: renal p53 downregulation and hepatic caspase-3 upregulation in neonatal mice, supported with in silico studies
(Springer Science and Business Media Deutschland GmbH, 2026-05-11) Ahmed Said; Ayman A. Diab; Gehan Safwat; Amira S. AbdElkhalek; Arwa Kohela; M. Yasser Alsedfy; Marolina Youssry; Ganna Ahmed; Karima Nasraldin
Caffeine intake during pregnancy is widespread, yet it continues to raise public health concerns due to its implications for embryogenesis. Despite extensive research, the long-term consequences of prolonged high-dose caffeine exposure on critical phases of fetal organogenesis remain incompletely characterized. This study was aimed at investigating the impact of prolonged prenatal caffeine administration on kidney and liver development in Swiss albino mice. Pregnant mice (n = 18) received daily IP injections of caffeine (90 mg/kg/day) or saline from GD 8.5 to 18.5. Neonatal offspring were assessed for growth parameters, and molecular as well as histological analyses were performed on kidney and liver tissues, focusing on apoptosis-related markers p53 and caspase-3. Caffeine-exposed offspring showed significant growth restriction with reduced body size and weight and shorter crown-rump length. In the kidneys, caffeine caused marked suppression of p53 expression, a 3.5-fold increase in caspase-3 activity, and significant tubular disorganization. The liver maintained p53 expression but exhibited a significant increase in caspase-3 protein. Our in silico transcriptomic analysis revealed caffeine-induced dysregulation of cholesterol biosynthesis pathways in liver cells and ribosome biogenesis in renal cells, identifying key hub genes linked to lipid metabolism and RNA processing. These findings support our in vitro observations of p53 downregulation and caspase-3 activation, suggesting caffeine’s role in modulating apoptosis and cell cycle regulation. Prolonged high-dose caffeine exposure induces fetal growth impairment and organ-specific developmental toxicity, with different apoptotic dysregulation patterns in the kidneys by the p53-dependent pathway and in the liver by caspase-3-mediated pathways. This study highlights the importance of carefully considering caffeine dosage and duration of exposure during early pregnancy.
Evaluation of innovative dual-layer modified polyethersulfone membranes in the control of biofouling
(Nature Research, 2026-05-07) Nermine Nasser; Mohamed Salah El-Din Hassouna; Noha Salem; Ranya Amer; Sherif H. Kandil; Norhan Nady
This study uniquely demonstrates the innovative combination of aminophenol and phenolic acids through laccase-catalyzed processes on polyethersulfone (PES) surfaces. Firstly, PES membranes were modified via laccase-catalyzed polymerization of 3-aminophenol (3-AP), then a second layer with either 4-hydroxybenzoic acid (B), gallic acid (G), syringic acid (S), or vanillic acid (V) was integrated using the same laccase-catalyzed polymerization method. The B/3-AP/PES and S/3-AP/PES membranes (using 4-hydroxybenzoic acid and syringic acid as the second modification layer) had better hydrophilicity as the contact angle was reduced from 44.1° (one-layered 3-AP/PES) to 23.8° and 27.9°, respectively, alongside significant increases in the root-mean-square (RMS) roughness (59 nm for unmodified PES vs. 180.2 and 385 nm for B/3-AP/PES and S/3-AP/PES, respectively). Atomic Force Microscopy (AFM) imaging revealed brush-like architectures for 3-AP/PES and B/3-AP/PES, while it was pancake-like in S/3-AP/PES. MIC testing showed that bacterial inhibition could reach 99.9%. Microbial evaluations of biofilm formation showed that B/3-AP/PES gave the highest reduction in the detached bacterial count (77%); this was concomitant with lower hemocytometer cell counts. Scanning Electron Microscopy (SEM) confirmed the reduction of bacterial adhesion. This study introduces a new approach of enzymatically grafting aminophenol layer as a stable anchoring platform for dual-layered modification by natural phenolic compounds.
Under the Gaze of Ra: Surveillance and Subjection in Sonallah Ibrahim’s The Committee and Basma Abdel Aziz’s The Queue
(Surveillance Studies Network, 2026-03-22) Noha Abdelmotagally; Samar Abdelsalam; Fadwa Abdelrahman
This paper examines how surveillance socially controls individuals and designates them as subjects in Sonallah Ibrahim’s The Committee (2001) and Basma Abdel Aziz’s The Queue (2016b), employing surveillance studies and Louis Althusser’s (1971) theory of state apparatuses—focusing equally on both repressive state apparatuses (RSAs) and ideological state apparatuses (ISAs)—and concept of interpellation as its theoretical framework. In The Committee, interpellation is enforced through the state apparatuses; characters internalize their being under the constant gaze of the State and develop a kind of self-discipline that ensures their automatic conformity to the dominant ideology. Similarly, The Queue portrays the effects of social control and surveillance on individuals. The queue becomes a symbol of the complete subjection of the people to the almost incomprehensible dictates of the authoritarian regime. By analyzing the dynamics of power and the interplay of surveillance and/by the state apparatuses in these two novels, this paper demonstrates how surveillance operates as a powerful mechanism of social control, shaping individual consciousness and behavior in profound ways. It highlights the enduring relevance of surveillance studies in understanding the complex relationship between the power of the gaze and individual subjection in contemporary societies.
Biofilm System Performance in Biological Treatment by Using Trickling Filter
(Springer Nature, 2026-04-01) Ahmed Labena; Reem Hatem Elhady; Diana S. Raie
The present chapter discusses bio-trickling filters (BTFs) as an effective and low-maintenance solution for treating various pollutants in wastewater. We overview the BTF structure, operation system, biofilm structure, and its development on carriers or media in the BTFs. The chapter explores the role of microorganisms that developed in the biofilms and their positive and negative impacts. Additionally, it summarises different techniques of adherence of microorganisms to develop biofilms and their impact on BTFs. It explains the processes of removing pollutants from wastewater using BTFs, including heavy metals, organic matter, odour, and greenhouse gases (GHGs). Factors affecting the BTFs will be described, such as changes in contact time, pH value, temperature, nutrients, water content, trickling liquid velocity, and their correlation to the uptake efficiency of biofilms.
Thermal stability and decomposition pathways of zeolitic imidazolate frameworks for future catalytic thermochemical applications
(Elsevier B.V., 2026-05-05) Samy Yousef; Justas Eimontas; Nerijus Striūgas; Vilmantė Kudelytė; Mohammed Ali Abdelnaby
Metal-organic frameworks (MOFs) have recently gained attention as catalysts in catalytic pyrolysis (CP); however, their application is constrained by thermal instability at high operating temperatures, which calls for work to find the most suitable class for this purpose. In this context, this work introduces zeolitic imidazolate frameworks (ZIFs) as thermally stable and commercially available MOF candidates for CP applications by investigating their decomposition behaviour, kinetics, and structure stability. Thermogravimetric analysis (TGA) was carried out under various heating rates, coupled with TG-FTIR and GC/MS to observe evolved vapors. The kinetic and thermodynamic characteristics were simulated using linear and nonlinear models, and a trained artificial neural network (ANN) was used to predict decomposition regions. The results showed that ZIF-67 and ZIF-8 exhibited high thermal stability up to 580 °C and 600 °C, respectively, followed by rapid degradation releasing 1H-imidazole, 2-methyl- compound. ZIF-8 exhibited higher activation energy (450–461 kJ/mol) compared to 340–352 kJ/mol (ZIF-67), with both materials following endothermic decomposition approach. The ANN model successfully captured the decomposition region (R2 ≥ 0.999). Finally, the structure analysis showed that porosity loss rises with faster heating rates, with ZIF-67 proving more stable than ZIF-8, especially at higher rates. SEM-EDX results also confirmed that cobalt nodes are more stable than zinc. These results demonstrate that ZIFs have high thermal and porosity stability at low heating rates, while at higher heating rates, ZIF-67 exhibits exceptional stability, making it a promising catalyst for the CP of feedstocks with decomposition temperatures below 580 °C (such as biomass and plastic waste).