The Usage of Albedo Orange Methanol and Ethanol Extraction as Anticancer Agent

Abstract

The present study aimed to evaluate the anticancer activity of methanol/ ethanol Orange Albedo extracts where test extracts showed anti-proliferative activity. Also, the test extract viability % were concentration, IC 50 value and cell type dependent. Also, there was a significant up / down regulation of pro/ anti apoptotic genes. Also the cell cycle profile indicated cell arrest at the G2 / M phase compared with the control accompanied with apoptotic profile significantly elevated than non treated cell control (P<0.05).