Synthesis and in vitro antitumor activity of some new Mannich bases

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorKandeel M.M.
dc.contributor.authorAbdou N.A.
dc.contributor.authorKadry H.H.
dc.contributor.authorEl-Masry R.M.
dc.contributor.otherOctober University for Modern Sciences and Arts MSA
dc.date.accessioned2020-01-09T20:42:29Z
dc.date.available2020-01-09T20:42:29Z
dc.date.issued2013-01-06
dc.descriptionH-Index 52
dc.description.abstractTwo series of Novel Mannich bases has been synthesized from chalcones 3 and 7 and evaluated for their in vitro cytotoxic activity. Out of the newly synthesized compounds, four derivatives 4a, 4b, 4e, 4f were selected by the National Cancer Institute (NCI) to be evaluated for their in-vitro antitumor activity by in-vitro disease-oriented human cells screening panel assay. All the tested compounds exhibited a broad spectrum of antitumor activity against renal cancer UO-31.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=19700175055&tip=sid&clean=0
dc.identifier.issn9744290
dc.identifier.urihttps://t.ly/2dwYb
dc.language.isoEnglishen_US
dc.publisherSphinx Knowledge House
dc.relation.ispartofseriesInternational Journal of ChemTech Research ; Vol.5, No.1, pp 401-408
dc.subjectAntitumor activity , cytotoxicity , Chalcones , Mannich bases , Synthesisen_US
dc.titleSynthesis and in vitro antitumor activity of some new Mannich basesen_US
dc.typeArticleen_US
dcterms.sourceScopus

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