The reaction of cyclohexan-1,3-dione with cyanomethylenes: Synthesis of thiophenes and their fused derivatives with antifungal activities

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorMohareb R.M.
dc.contributor.authorSherif S.M.
dc.contributor.authorMoustafa H.E.-D.
dc.contributor.otherDepartment of Organic Chemistry
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherOctober University for Modern Sciences and Arts (MSA)
dc.contributor.otherEl-Wahaat Road
dc.contributor.otherOctober
dc.contributor.otherA. R.
dc.contributor.otherEgypt; Department of Chemistry
dc.contributor.otherFaculty of Science
dc.contributor.otherCairo University
dc.contributor.otherGiza
dc.contributor.otherA. R.
dc.contributor.otherEgypt
dc.date.accessioned2020-01-25T19:58:33Z
dc.date.available2020-01-25T19:58:33Z
dc.date.issued2009
dc.descriptionScopus
dc.description.abstract2-Amino-7-oxotetrahydrobenzo[b]thiophenes 3a,b were prepared according to the Gewald procedure. Their reactivity toward a variety of chemical reagents was studied to give annulated heterocycles with potential bio-responses.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=25288&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.1080/10426500802421127
dc.identifier.doiPubMed ID :
dc.identifier.issn10426507
dc.identifier.otherhttps://doi.org/10.1080/10426500802421127
dc.identifier.otherPubMed ID :
dc.identifier.urihttps://t.ly/03lm5
dc.language.isoEnglishen_US
dc.relation.ispartofseriesPhosphorus, Sulfur and Silicon and the Related Elements
dc.relation.ispartofseries184
dc.subjectAnnulated derivativesen_US
dc.subjectPyridineen_US
dc.subjectThiazoleen_US
dc.subjectThiopheneen_US
dc.titleThe reaction of cyclohexan-1,3-dione with cyanomethylenes: Synthesis of thiophenes and their fused derivatives with antifungal activitiesen_US
dc.typeArticleen_US
dcterms.isReferencedByPozharskii, A.F., Soldatenkov, A.T., Katritzky, A.R., (1997) Heterocycles in Life and Society, , Wiley, Chichester, UK; Queiroz, M.J.R.P., Ferreira, I.C.F.R., Calhelha, R.C., Estevinho, L.M., (2007) Bioorg. Med. Chem., 15 (4), p. 1788; Gilchrist, T.L., (2001) J. Chem. Soc., Perkin Trans., 1, p. 2491; Horton, D.A., Bourne, G.T., Smythe, M.L., (2003) Chem. Rev., 103, p. 893; Donnelly, D.M.X., Meegan, M.J., (1984) Comprehensive Heterocyclic Chemistry, 4, p. 657. , A. R. Katritzky and C. W. Rees, Eds. Elsevier Science & Technology, USA; Nakamura, I., Yamamoto, Y., (2004) Chem. Rev., 104, p. 2127; Li, J.J., Gribble, G.W., (2000) Palladium in Heterocyclic Chemistry, , Pergamon, Amsterdam; Cacchi, S., Fabrizi, G., Goggiomani, A., (2002) Heterocycles, 56, p. 613; Cacchi, S., (1999) J. Organomet. Chem., 42, p. 576; Cacchi, S., Arcadi, A., (2002) Handbook of Organopalladium Chemistry for Organic Synthesis, 2, p. 2193. , E. I. Negishi, Ed. Wiley, New York; Pal, M., Subramanian, V., Yeleswarapu, K.R., (2003) Tetrahedron Lett., 44, p. 8221; Dai, W.M., Lai, K.W., (2002) Tetrahedron Lett., 43, p. 9377; Flynn, B.L., Hamel, E., Jung, M.K., (2002) J. Med. Chem., 45, p. 2670; Hu, Y., Yang, Z., (2001) Org. Lett., 3, p. 1387; Mohareb, R.M., Sherif, S.M., Gaber, H.M., Ghabrial, S.S., Aziz, S.I., (2004) Heteroatom Chem., 15 (4), p. 15; Mohareb, R.M., Sherif, S.M., Gaber, H.M., Ghabrial, S.S., Aziz, S.I., (2003) Heteroatom Chem., 14 (5), p. 459; Hilmy, K., Mohareb, R.M., El-Torgoman, A.M., Sharawy, Y., (2003) Phosphorous Sulfur, and Silicon, 178 (8), p. 1667; Gewald, K., Schinke, E., Bottcher, H., (1966) Chem. Ber., 94, p. 99; Schafer, H., Jablohoff, H., Hentschel, M., Gewald, K., (1984) J. Prakt. Chem., 326 (6), p. 916; Mohareb, R.M., Shams, H.Z., El-Khooly, Y.M., Azzam, R., (1999) Phosphorous Sulfur, and Silicon, 155, p. 215; Mohareb, R.M., Aziz, S.I., Abdel-Sayed, N.I., Elbanna, A.A., (1999) J. Chem. Res. (S), p. 10. , (M), 0101 (1999)
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