State of the art in epitope mapping and opportunities in COVID-19

dc.AffiliationOctober university for modern sciences and Arts MSA
dc.contributor.authorHamed, Samira M
dc.contributor.authorSakr, Masarra M
dc.contributor.authorEl-Housseiny, Ghadir S
dc.contributor.authorWasfi, Reham
dc.contributor.authorAboshanab, Khaled M
dc.date.accessioned2023-03-10T08:58:36Z
dc.date.available2023-03-10T08:58:36Z
dc.date.issued2023-03-06
dc.descriptionSJR 2024 0.536 Q2 H-Index 47
dc.description.abstractThe understanding of any disease calls for studying specific biological structures called epitopes. One important tool recently drawing attention and proving efficiency in both diagnosis and vaccine development is epitope mapping. Several techniques have been developed with the urge to provide precise epitope mapping for use in designing sensitive diagnostic tools and developing rpitope-based vaccines (EBVs) as well as therapeutics. In this review, we will discuss the state of the art in epitope mapping with a special emphasis on accomplishments and opportunities in combating COVID-19. These comprise SARS-CoV-2 variant analysis versus the currently available immune-based diagnostic tools and vaccines, immunological profile-based patient stratification, and finally, exploring novel epitope targets for potential prophylactic, therapeutic or diagnostic agents for COVID-19.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=21100854839&tip=sid&clean=0
dc.identifier.citationHamed, S. M., Sakr, M. M., El-Housseiny, G. S., Wasfi, R., & Aboshanab, K. M. (2023). State of the art in epitope mapping and opportunities in COVID-19. Future Science OA, 9(1). https://doi.org/10.2144/fsoa-2022-0048 ‌
dc.identifier.doihttps://doi.org/10.2144/fsoa-2022-0048
dc.identifier.other10.2144/fsoa-2022-0048 - C 202
dc.identifier.urihttp://repository.msa.edu.eg/xmlui/handle/123456789/5414
dc.language.isoen_USen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofseriesFuture Science OA ; 16(3-06):FSO832
dc.subjectdiagnostic tools •en_US
dc.subjectepitope-based vaccines •en_US
dc.subjectepitope mapping •en_US
dc.subjecthost-pathogen interface •en_US
dc.subjectSARS-CoV-2en_US
dc.titleState of the art in epitope mapping and opportunities in COVID-19en_US
dc.typeArticleen_US

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