Chemical and biological assessment of Tecoma x Smithii Hort.

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorSaleh N.A.
dc.contributor.authorEzzat, Shahira M
dc.contributor.authorEl-Kashoury E.-S.A.
dc.contributor.authorTaha K.F.
dc.contributor.otherMedicinal Plants Department
dc.contributor.otherNational Organization for Drug Control and Research
dc.contributor.otherPyramid Ave.
dc.contributor.other6 Abou Hazem Street
dc.contributor.otherCairo
dc.contributor.otherEgypt; Pharmacognosy Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherCairo University
dc.contributor.otherKasr El-Ainy Street
dc.contributor.otherCairo
dc.contributor.other11562
dc.contributor.otherEgypt; Pharmacognosy Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherOctober University for Modern Science and Arts (Shamsa
dc.contributor.otherMonsef
dc.contributor.otherGhamooshi
dc.contributor.otherand Verdian-rizi)
dc.contributor.other6th October City
dc.contributor.other12566
dc.contributor.otherEgypt
dc.date.accessioned2020-01-09T20:40:44Z
dc.date.available2020-01-09T20:40:44Z
dc.date.issued2019
dc.descriptionScopus
dc.descriptionMSA Google Scholar
dc.description.abstractSpectrophotometric quantitative determination of polyphenols, flavonoids, alkaloids, sterols, and carbohydrates of the leaves, flowers and fruits of Tecoma x smithii Will. Wats. was performed, as well as the lipoidal matter (unsaponifiable compounds and fatty acids methyl esters) that were investigated using gas chromatography-mass spectrometry (GC-MS). Representative aromatic acids where estimated for the three parts using HPLC. Polyphenols and flavonoids were most concentrated in the 70% ethanol extract of the leaves. The investigation of the ethyl acetate fraction of the 70% ethanol extract of the leaves resulted in isolation and identification of Chrysoeriol (E1), Luteolin (E2), and Caffeic acid (E3). Two other compounds were also isolated from the n-butanol fraction: Chlorogenic acid (B1) and Rutin (B2). The ethanolic and aqueous extracts of the leaves were evaluated for their acute toxicity, anti-inflammatory, antipyretic, analgesic, and anti-hyperglycemic activities. Both extracts were regarded safe and could significantly reduce the blood glucose level in alloxan- diabetic rats and showed a comparable antipyretic and analgesic effect to the reference standards used in the study. � 2019 Society of Pharmaceutical Sciences of Ankara (FABAD). All rights reserved.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=21374&tip=sid&clean=0
dc.identifier.doihttps://doi.org/
dc.identifier.issn13004182
dc.identifier.otherhttps://doi.org/
dc.identifier.urihttps://t.ly/VZZLM
dc.language.isoEnglishen_US
dc.publisherWiley-Blackwell
dc.publisherSociety of Pharmaceutical Sciences of Ankara (FABAD)en_US
dc.relation.ispartofseriesFabad Journal of Pharmaceutical Sciences
dc.relation.ispartofseries44
dc.subjectOctober University for Modern Sciences and Arts
dc.subjectUniversity for Modern Sciences and Arts
dc.subjectMSA University
dc.subjectجامعة أكتوبر للعلوم الحديثة والآداب
dc.subjectAntidiabeticen_US
dc.subjectGallic aciden_US
dc.subjectGC-MSen_US
dc.subjectNonacosaneen_US
dc.subjectQuercetinen_US
dc.subjectSitosterolen_US
dc.subject1 hexadeceneen_US
dc.subject1 hexadecyneen_US
dc.subject1 nonadeceneen_US
dc.subject1 octadeceneen_US
dc.subject2 phenyl dodecaneen_US
dc.subject2 phenyl tridecaneen_US
dc.subject2 phenyl undecaneen_US
dc.subject3 phenyl dodecaneen_US
dc.subject3 phenyl tridecaneen_US
dc.subject3 phenyl undecaneen_US
dc.subject5 eicoseneen_US
dc.subject5 phenyl tridecaneen_US
dc.subject5 phenyl undecaneen_US
dc.subject6 phenyl tridecaneen_US
dc.subject6,10,14 trimethyl 2 pentadecanoneen_US
dc.subject6,6 dimethyl cyclooct 4 enoneen_US
dc.subjectantidiabetic agenten_US
dc.subjectantiinflammatory agenten_US
dc.subjectantipyretic analgesic agenten_US
dc.subjectcyclohexadecaneen_US
dc.subjectheptadecaneen_US
dc.subjectindometacinen_US
dc.subjectmetforminen_US
dc.subjectneophytadieneen_US
dc.subjectnonadecaneen_US
dc.subjectparacetamolen_US
dc.subjectplant extracten_US
dc.subjectstearic aciden_US
dc.subjecttecoma x smithii hort extracten_US
dc.subjectunclassified drugen_US
dc.subjectunindexed drugen_US
dc.subjectanimal experimenten_US
dc.subjectantidiabetic activityen_US
dc.subjectantiinflammatory activityen_US
dc.subjectArticleen_US
dc.subjectchemical analysisen_US
dc.subjectcomparative studyen_US
dc.subjectcontrolled studyen_US
dc.subjectdrug determinationen_US
dc.subjectdrug identificationen_US
dc.subjectdrug potencyen_US
dc.subjectdrug screeningen_US
dc.subjectfloweren_US
dc.subjectfruiten_US
dc.subjecthigh performance liquid chromatographyen_US
dc.subjectlimit of quantitationen_US
dc.subjectmass fragmentographyen_US
dc.subjectnonhumanen_US
dc.subjectplant leafen_US
dc.subjectquantitative analysisen_US
dc.subjectraten_US
dc.subjectTecomaen_US
dc.subjectTecoma x smithii horten_US
dc.titleChemical and biological assessment of Tecoma x Smithii Hort.en_US
dc.typeArticleen_US
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