Adiponectin and pro-inflammatory cytokines in obese diabetic boys

dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorEl-Mesallamy H.O.
dc.contributor.authorHamdy N.M.
dc.contributor.authorIbrahim S.M.
dc.contributor.otherBiochemistry Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherAin Shams University
dc.contributor.otherCairo
dc.contributor.otherEgypt; Modern Sciences and Arts University
dc.contributor.otherCairo
dc.contributor.otherEgypt
dc.date.accessioned2020-01-25T19:58:29Z
dc.date.available2020-01-25T19:58:29Z
dc.date.issued2011
dc.descriptionScopus
dc.description.abstractAdiponectin serum levels were significantly lower in obese diabetic than in non-obese healthy boys (P<0.001). Circulating soluble E-selectin levels was significantly higher in obese diabetic boys than the healthy non-obese (P<0.01). There were significant inverse correlations between adiponectin and sE-selectin, hsCRP, IL-1?, and MCP-1 and positively with NOx. We conclude that sE-selectin and MCP-1 may represent a link between obesity and related co-morbidities in children and adults.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=15030&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.1007/s13312-011-0125-7
dc.identifier.doiPubMed ID 22080689
dc.identifier.issn196061
dc.identifier.otherhttps://doi.org/10.1007/s13312-011-0125-7
dc.identifier.otherPubMed ID 22080689
dc.identifier.urihttps://t.ly/ZEKlB
dc.language.isoEnglishen_US
dc.relation.ispartofseriesIndian Pediatrics
dc.relation.ispartofseries48
dc.subjectAdiponectinen_US
dc.subjectChildrenen_US
dc.subjectEgypten_US
dc.subjectInflammationen_US
dc.subjectObesityen_US
dc.subjectsE-selectinen_US
dc.subjectType 2 Diabetesen_US
dc.subjectadiponectinen_US
dc.subjectC reactive proteinen_US
dc.subjectendothelial leukocyte adhesion molecule 1en_US
dc.subjectglucoseen_US
dc.subjecthigh density lipoprotein cholesterolen_US
dc.subjectinsulinen_US
dc.subjectinterleukin 1betaen_US
dc.subjectlipiden_US
dc.subjectmonocyte chemotactic protein 1en_US
dc.subjectnitric oxideen_US
dc.subjectadolescenten_US
dc.subjectadulten_US
dc.subjectadulthooden_US
dc.subjectage distributionen_US
dc.subjectarticleen_US
dc.subjectbody massen_US
dc.subjectchilden_US
dc.subjectclinical articleen_US
dc.subjectcontrolled studyen_US
dc.subjectglucose blood levelen_US
dc.subjectglucose metabolismen_US
dc.subjecthumanen_US
dc.subjectinflammationen_US
dc.subjectinsulin resistanceen_US
dc.subjectmaleen_US
dc.subjectnon insulin dependent diabetes mellitusen_US
dc.subjectobesityen_US
dc.subjectprotein blood levelen_US
dc.subjectschool childen_US
dc.subjectAdiponectinen_US
dc.subjectAdolescenten_US
dc.subjectAdulten_US
dc.subjectBody Mass Indexen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectCase-Control Studiesen_US
dc.subjectChemokine CCL2en_US
dc.subjectChilden_US
dc.subjectCytokinesen_US
dc.subjectDiabetes Mellitus, Type 2en_US
dc.subjectE-Selectinen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.subjectNitric Oxideen_US
dc.subjectObesityen_US
dc.titleAdiponectin and pro-inflammatory cytokines in obese diabetic boysen_US
dc.typeArticleen_US
dcterms.isReferencedByYudkin, J.S., Adipose tissue, insulin action and vascular disease: Inflammatory signals (2003) International Journal of Obesity, 27 (SUPPL. 3), pp. S25-S28. , DOI 10.1038/sj.ijo.0802346; Sartipy, P., Loskutoff, D.J., Monocyte chemoattractant protein 1 in obesity and insulin resistance (2003) Proceedings of the National Academy of Sciences of the United States of America, 100 (12), pp. 7265-7270. , DOI 10.1073/pnas.1133870100; Winer, J.C., Zern, T.L., Taksali, S.E., Dziura, J., Cali, A.M.G., Wollschlager, M., Seyal, A.A., Caprio, S., Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome (2006) Journal of Clinical Endocrinology and Metabolism, 91 (11), pp. 4415-4423. , http://jcem.endojournals.org/cgi/reprint/91/11/4415, DOI 10.1210/jc.2006-0733; Gilardini, L., McTernan, P.G., Girola, A., Da Silva, N.F., Alberti, L., Kumar, S., Invitti, C., Adiponectin is a candidate marker of metabolic syndrome in obese children and adolescents (2006) Atherosclerosis, 189 (2), pp. 401-407. , DOI 10.1016/j.atherosclerosis.2005.12.021, PII S0021915005008440; Rosa, J.S., Flores, R.L., Oliver, S.R., Pontello, A.M., Zaldivar, F.P., Galassetti, P.R., Sustained IL-1b, IL-4, and IL-6 elevations following correction of hyperglycemia in children with type 1 diabetes mellitus (2008) Pediatric Diabetes, 9, pp. 9-16. , 18211631 10.1111/j.1399-5448.2007.00243.x 1:CAS:528:DC%2BC3cXhtVSgsr7K; Desideri, G., De Simone, M., Iughetti, L., Rosato, T., Iezzi, M.L., Marinucci, M.C., Cofini, V., Ferri, C., Early activation of vascular endothelial cells and platelets in obese children (2005) Journal of Clinical Endocrinology and Metabolism, 90 (6), pp. 3145-3152. , http://jcem.endojournals.org/cgi/reprint/90/6/3145, DOI 10.1210/jc.2004-1741
dcterms.sourceScopus

Files

Original bundle

Now showing 1 - 2 of 2
Loading...
Thumbnail Image
Name:
avatar_scholar_256.png
Size:
6.31 KB
Format:
Portable Network Graphics
Description:
Loading...
Thumbnail Image
Name:
07e639b9c8a81167f0b6ae65c63660c928eb.pdf
Size:
22.28 KB
Format:
Adobe Portable Document Format
Description: