Adiponectin and pro-inflammatory cytokines in obese diabetic boys

Abstract

Adiponectin serum levels were significantly lower in obese diabetic than in non-obese healthy boys (P<0.001). Circulating soluble E-selectin levels was significantly higher in obese diabetic boys than the healthy non-obese (P<0.01). There were significant inverse correlations between adiponectin and sE-selectin, hsCRP, IL-1?, and MCP-1 and positively with NOx. We conclude that sE-selectin and MCP-1 may represent a link between obesity and related co-morbidities in children and adults.

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