Adiponectin and pro-inflammatory cytokines in obese diabetic boys
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Date
2011
Authors
Journal Title
Journal ISSN
Volume Title
Type
Article
Publisher
Series Info
Indian Pediatrics
48
48
Scientific Journal Rankings
Abstract
Adiponectin serum levels were significantly lower in obese diabetic than in non-obese healthy boys (P<0.001). Circulating soluble E-selectin levels was significantly higher in obese diabetic boys than the healthy non-obese (P<0.01). There were significant inverse correlations between adiponectin and sE-selectin, hsCRP, IL-1?, and MCP-1 and positively with NOx. We conclude that sE-selectin and MCP-1 may represent a link between obesity and related co-morbidities in children and adults.
Description
Scopus
Keywords
Adiponectin, Children, Egypt, Inflammation, Obesity, sE-selectin, Type 2 Diabetes, adiponectin, C reactive protein, endothelial leukocyte adhesion molecule 1, glucose, high density lipoprotein cholesterol, insulin, interleukin 1beta, lipid, monocyte chemotactic protein 1, nitric oxide, adolescent, adult, adulthood, age distribution, article, body mass, child, clinical article, controlled study, glucose blood level, glucose metabolism, human, inflammation, insulin resistance, male, non insulin dependent diabetes mellitus, obesity, protein blood level, school child, Adiponectin, Adolescent, Adult, Body Mass Index, C-Reactive Protein, Case-Control Studies, Chemokine CCL2, Child, Cytokines, Diabetes Mellitus, Type 2, E-Selectin, Humans, Male, Nitric Oxide, Obesity