Extraction and isolation of cannabinoids

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Date

2024-01-01

Journal Title

Journal ISSN

Volume Title

Type

Article

Publisher

Elsevier

Series Info

Cannabis and Khat in Drug Discovery: the Discovery Pipeline and the Endocannabinoid System ; Pages 79 - 1171 January 2024

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Abstract

Cannabis sativa L. is one of the most important medicinal plants that belongs to the family Cannabaceae. C. sativa is a herbaceous flowering plant that is indigenous to eastern Asia, but it is now cultivated worldwide due to the importance of its active constituents known as cannabinoids. Due to the growing interest in these compounds, various methods for their extraction and isolation were proposed. In this chapter, we will have an overview about the conventional and nonconventional methods for extraction of cannabinoids both from plant material and from biological samples for forensic purposes. Also we will review the methods for isolation of such compounds from different types of extracts as well as the modern methods for metabolomics and chemometric tools for analysis of cannabinoids.

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Keywords

analytical chemistry, biochemistry applications, cannabidiol, centrifugal partition chromatography, DLLME, drug, drug analysis, food chemistry, forensic, metabolomics, microextraction, microwave-assisted extraction, organic chemistry methods, pharmacology discipline, preparative chromatography, sample treatment, SFE, SPMEM, supercritical fluid extraction, Tetrahydrocannabinols, transformation

Citation

Salem, M. A., Ibrahim, R. M., Baki, P. M. A., Osman, S. M., & Ezzat, S. M. (2024). Extraction and isolation of cannabinoids. In Elsevier eBooks (pp. 79–117). https://doi.org/10.1016/b978-0-323-95927-8.00006-2