Faculty Of Pharmacy Graduation Project 2019 - 2020

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Browsing Faculty Of Pharmacy Graduation Project 2019 - 2020 by Subject "(MCC)"

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    Utilization and characterization of microcrystalline cellulose (MCC) obtained from different natural biomasses as an economic excipient
    (MSA university Faculty of pharmacy, 2020) Emad Hussein Nada, Marwan; Khaled Sayed Hassan, Mayada; Mohamed Mahmoud Elhantiry, Nada; abd elrahman Eldeeb, Rawan
    Many biomasses are burnt daily to get rid of them as they are available in a large amount and the human does not want them. This action can cause an environmental problem like air pollution. Also these biomasses like water hyacinth, rice husk and wheat husk are available, cheap materials which contain a high percent of lignin and cellulose; they can be used in an ecofriendly method as they can be used in the extraction of the MCC which works as an adsorbent. MCC can be used as an adsorbent for the pollutants in the contaminated water. MCC is a depolymerized alpha cellulose pure precursor. The MCC also can be used in the pharmaceutical field as a bulking agent, fat substitute, emulsifier, thickener and binder in tablets. MCC can be obtained from the three different biomasses by steam explosion, acid hydrolysis, reactive extrusion and enzyme mediated. In our study we used the acidic hydrolysis in the extraction of the microcrystalline cellulose from the three biomasses. We were looking forward for the extract of the microcrystalline cellulose by using the minimal cost, most effective and ecofriendly method. After that comparing the extracted microcrystalline cellulose with the microcrystalline cellulose found in the market according to the cost, NMR, SEM, FT -IR and XRD.