MSA Repository "MSAR"

MSAR University's Digital Repository is a documentation and digitization of all university outcomes that are of effective value in the scientific and academic community and reflects the university's image, work, and effective contribution to society Through MSAR Digital Repository, the university managed to collect, store, archive and publish digital content - including documents, audio files, images and data sets - all in a safe place. MSAR is one of the strongest University Digital Repositories in Egypt and documented in the DSPACE community with its latest versions.

Communities in DSpace

Select a community to browse its collections.

Now showing 1 - 5 of 5

MSA Journals 134
A Full content for MSA university Faculties Journals
MSA University Academic Graduation Projects 1142
A Full content for msa university Distinguished Graduation Projects Yearbook
MSA University Academic Research 3781
MSA University Campus 2
Images for MSA University " sites - building - landscape "
RESEARCH & LANGUAGES CENTERS 18

Recent Submissions

Inhibition of bacterial attachment to polyethersulfone membranes using aminophenol compounds in static and continuous flow systems
(Nature Research, 2025-08-21) Mohamed Salah El-Din Hassouna; Nermine Nasser; Noha Salem; RanyaAmer; Sherif H. Kandil; Norhan Nady
Biofouling is the most challenging problem associated with membrane-based filtration technology. Biofouling deteriorates membranes used in filtration process and decreases the efficiency of membrane productivity used in separation fields, thus increasing the technology cost of membrane-based filtration process. Several approaches exist to control biofouling; membrane surface modification has recently been used to resist bacterial attachment and biofilm formation. In this study, the poly(ethersulfone) (PES) membrane was modified by three different poly(aminophenol) as bacterial anti-attachment compounds. Each one of poly(2-aminophenol), poly(3-aminophenol), and 4-aminophenol oligomers, was incorporated separately. In this test, two bacterial strains; Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive), were used through both static and continuously flowing fluid bacterial suspension systems to evaluate the bacterial anti-attachment performance of the modified PES membranes. The results indicated that the brush-like structured layer of poly(3-aminophenol) can resist bacterial attachment under static conditions. In addition, poly(2-aminophenol) gave better impedance of bacterial attachment in the continuously flowing fluid system. This work revealed up to 90% reduction of attached bacteria on modified membranes under static condition and up to 62% under continuously flowing condition.
Effects of High-concentration Doxycycline versus Chlorhexidine as Dentin Pretreatment on Composite Resin Micro-tensile Bond Strength
(Bentham Science Publishers, 2025-01-18) Rasha R. Basheer; Dalia M. Abouelmagd
Objective To assess the effect of 10% doxycycline (DOX) compared to 2% chlorhexidine (CHX) on the longevity of dentin-bond strength. Methods Sixty-six extracted molars were collected and prepared and divided into two groups based on the test to be performed. Group I (n=48) for the micro-tensile bond strength (µTBS) test and Group II (n=18) for the confocal laser scanning microscopy (CLSM) test. Group I was divided into 3 subgroups (n=16) according to pretreatment agent following acid etching. Group A (control): without pretreatment, group B: 10% Doxycycline pretreatment, Group C: 2% Chlorhexidine pretreatment. Palfique universal bond (PU) and Composite resin were applied according to the manufacturer's instructions. Group II was divided into 3 subgroups (n=6) based on the same pretreatment protocols used in Group I. However, for resin-dentin bond evaluation using CLSM, 0.1 mg/mL Rhodamine B fluorescent dye was mixed with the adhesive. After that, all subgroups of group I and group II were subdivided into 2 subdivisions:(T1) without thermocycling and (T2) thermocycling for 10000 cycles. µTBS testing was achieved via a digital universal testing machine. The failure mode was tested by a stereomicroscope (30x magnification). Results Intergroup comparison of mean µTBS values (MPa) was performed using one-way ANOVA, then by Tukey post-hoc test with statistical significance at p ≤ 0.016. In contrast, intragroup comparison was achieved using a paired t-test with a statistical significance of p ≤ 0.05. Comparison between categorical data was made using a chi-square test. The 10% DOX pretreatment group showed significantly higher µTBS values than CHX and the control group with and without thermocycling (p < 0.001). No statistically significant difference in failure modes was recorded among groups without and with thermocycling. There was no correlation between µTBS and failure mode performed using Spearman’s rank correlation. CLSM revealed that the 10% DOX group exhibited greater resin infiltration with a thicker hybrid layer. Both matrix metalloproteinase (MMP) inhibitors created a uniform hybrid layer. Discussion 10% DOX showed the highest MMP inhibition, the higher concentration of DOX may have increased the inactivation effect of DOX on MMPs. Conclusion Pre-treatment with MMP inhibitors might have inhibited the degradation of resin-dentin interfaces. In addition, 10% DOX pretreatment for 60 seconds after etching appears to be more efficient in enhancing the durability of the bond. Additionally, the composition of PU may influence bond strength, warranting further investigation. Moreover, thermocycling may adversely impact the micro-tensile bond strength.
Hybrid Anomaly Detection in Spacecraft Telemetry Data Using Sparse Feature-Based Methods and Spatial-Temporal Generative Adversarial Networks
(IOP Publishing Ltd., 2025-05-12) Amr Akl; Hatem Elattar
Anomaly detection in spacecraft telemetry data is critical for ensuring mission success and operational reliability. However, the high dimensionality, complex temporal dynamics, and multivariate nature of telemetry data pose significant challenges for traditional anomaly detection methods. This paper proposes a hybrid anomaly detection system that combines Sparse Feature-Based Anomaly Detection (SFAD) and Spatial-Temporal Generative Adversarial Networks (ST-GAN) to address these challenges. The SFAD module reduces dimensionality and extracts sparse features from telemetry data, while the ST-GAN module captures temporal dependencies and spatial correlations between parameters. Additionally, an adaptive thresholding mechanism is introduced to dynamically adjust the anomaly detection threshold, reducing false positives and improving robustness. The proposed system is evaluated on the SMAP and MSL datasets, demonstrating superior performance in terms of Precision, Recall, and F1-Score compared to state-of-the-art methods such as LSTM-GAN, GRU-VAE, and Isolation Forest. The results show that the hybrid approach is particularly effective at detecting multivariate and contextual anomalies, which are often missed by traditional methods. The system’s ability to perform near real-time anomaly detection makes it suitable for practical spacecraft monitoring applications. This work contributes to the field of telemetry analysis by providing a robust, scalable, and accurate solution for anomaly detection, with potential applications in other domains such as industrial monitoring and autonomous vehicles.
Multifunctional Organoiron Dendrimers Functionalized with Zingerone: Synthesis, Characterization, and Promising Biomedical Applications
(Wiley-Blackwell Publishing Ltd, 2025-08-18) Tianyu Wei; Doaa Abou El-ezz; Badriah Saad Al-Farhan; Laila H. Abdel-Rahman; Amani A. Abdelghani
Organoiron dendrimers of three generations were synthesized via a divergent synthetic methodology starting from the pentaerythritol tetrakis (3-mercaptopropionate) core. These dendrimers were functionalized with zingerone, a natural compound renowned for its potent antioxidant and anti-inflammatory properties. Comprehensive characterizations were performed using a range of standard techniques, including 1H and 13C NMR spectroscopy, scanning electron microscopy, cyclic voltammetry, and thermogravimetric analysis. The thermogravimetric analysis results revealed a two-step degradation process: the initial phase corresponded to the detachment of cyclopentadienyliron moieties. In contrast, the second phase involved the decomposition of the organic framework. Higher-generation dendrimers demonstrated increased thermal stability, requiring elevated temperatures for the second degradation stage, demonstrating a clear correlation between molecular weight and stability. Electrochemical analyses revealed progressively more negative shifts and increased peak intensities in the reduction and oxidation peaks of higher-generation dendrimers, suggesting an increased density of electrochemically active sites. The scanning electron microscopy analysis revealed predominantly amorphous morphologies in the dendrimers, with higher-generation variants forming larger, crystalline aggregates characterized by sharply defined edges. Biological evaluations underscored the remarkable potential of the dendrimers. The third-generation dendrimer functionalized with zingerone exhibited superior antioxidant, antimicrobial, and antifungal activities compared to reference drugs. Meanwhile, the first-generation dendrimer demonstrated the most pronounced anti-inflammatory activity, although higher-generation dendrimers also delivered excellent results, particularly at higher concentrations. These results highlight the multifunctional properties of the synthesized organoiron dendrimers, paving the way for their application in biomedical and pharmaceutical fields.
Five-Step Plan for Proposing a Balanced HPLC Method via Fishbone Diagram: Untangling the Synergy of Efficiency and Sustainability, Application on the Analysis of Isoniazid, Pyrazinamide, and Rifampicin in a Fixed Dose Combination
(John Wiley and Sons Inc, 2025-08-13) Rana W. Gaber; Amr M. Mahmoud; Sarah S. Saleh
A five-step plan is presented to propose an HPLC method with the aid of the fishbone diagram to balance efficiency and sustainability. The five steps include method development, method optimization, method validation, greenness assessment, and sustainability profiling. A sensitive, accurate, robust, and rapid HPLC method has been developed for simultaneous determination and separation of anti-tubercular medications: rifampicin (RIF), isoniazid (INH), and pyrazinamide (PYR) in a fixed dose combination (FDC). The separation was attained by using a stationary phase Kromasil C18 column (250 mm, 4.6,5 µm), accompanied by a gradient mode of the mobile phase in which the first solution was made up by using acetonitrile and phosphate buffer in a ratio of 4:96 v/v, and the second solution consisted of phosphate buffer and acetonitrile in ratio 45:55 v/v. The method was optimized by applying a fractional factorial design (22), where the flow rate was set at 1.5 mL/min, the injection volume was 10 µL, and the detection was performed at 238 nm at a temperature of 35°C. The retention time for INH, PYR, and RIF were 3.82, 5.36, and 8.72 min (±0.02), respectively. The method was validated per the ICH guidelines, and the proposed method was found to be accurate, robust, precise, and selective. A design of experiment was established to assess the robustness of the study, where the obtained results proved that the developed method is robust. Two greenness tools, namely moGAPI and AGREE, were used to evaluate the method's greenness. In addition, the method was subjected to sustainability profiling using the EVG framework, where the suggested method was compared to other reported methods. The proposed method was found to be more sustainable and green, with a low negative impact on the environment.