Phenolic content, radical scavenging activity and cytotoxicity of Tamarix nilotica (Ehrenb.) bunge growing in Egypt

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorOmar Bakr, Riham
dc.contributor.authorAbd El-Aziz El Raey, Mohamed
dc.contributor.authorSeif Ashour, Rehab
dc.date.accessioned2020-02-23T06:54:03Z
dc.date.available2020-02-23T06:54:03Z
dc.date.issued2013
dc.descriptionMSA Google Scholaren_US
dc.description.abstractThe radical scavenging activity using 1,1-diphenyl, 2-picrylhydrazyl (DPPH) and cytotoxicity using sulphorhodamine B (SRB) assay of the aqueous methanolic extract of Tamarix nilotica (Ehrenb.) Bunge (Tamaricaceae) flowers and its subextracts (CHCl3, EtOAC and Pet.ether) were evaluated. Total phenolic and flavonoid contents were estimated using colorimetric assays. Ethyl acetate (EtOAc) showed the highest free radical scavenging activity with inhibitory concentration (IC50) 7.25 ± 0.86 µg/ml in addition to potential cytotoxic effect on liver cell carcinoma (Huh-7) (IC50 49.1 ± 0.96 µg/ml) whereas effect on lung cell carcinoma (A-549) was much lower (IC50: 137.9 ± 1.85 µg/ml). EtOAc had the highest flavonoid content (1.75 ± 1.5 mg/g QE) compared to other subextracts. These results indicated that ethyl acetate fraction contains bioactive compounds worthy of more sophisticated studies as free radical scavenger and cytotoxic agent.en_US
dc.description.sponsorshipJournal of Pharmacognosy and Phytotherapyen_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=19700175858&tip=sid&clean=0
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dc.identifier.doihttps://doi.org/10.5897/JPP11.065
dc.identifier.issn2141-2502
dc.identifier.otherhttps://doi.org/10.5897/JPP11.065
dc.identifier.urihttps://t.ly/VZKgy
dc.language.isoenen_US
dc.publisherJournal of Pharmacognosy and Phytotherapyen_US
dc.relation.ispartofseriesJournal of Pharmacognosy and Phytotherapy;Volume: 5 Issue: 3 Pages: 47-52
dc.subjectUniversity of Tamarix nilotica, cytotoxic activity, sulphorhodamine B (SRB) assay, scavenging activity, 1,1- diphenyl, 2-picrylhydrazyl (DPPH) assay, flavonoid, phenolic.en_US
dc.titlePhenolic content, radical scavenging activity and cytotoxicity of Tamarix nilotica (Ehrenb.) bunge growing in Egypten_US
dc.typeArticleen_US

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