Platelet-12 lipoxygenase targeting via a newly synthesized curcumin derivative radiolabeled with technetium-99m
Date
2016
Journal Title
Journal ISSN
Volume Title
Type
Article
Publisher
BIOMED CENTRAL LTD
Series Info
Chemistry Central Journal;VOL : 10 Issue : 1
Scientific Journal Rankings
Abstract
One of the most popular techniques for cancer detection is the nuclear medicine technique. The present research focuses on Platelet-12-lipoxygenase (P-12-LOX) as a promising target for treating and radio-imaging tumor tissues. Curcumin was reported to inhibit this enzyme via binding to its active site
Description
MSA Google Scholar
Keywords
Platelet-12 lipoxygenase, Curcumin, Technetium-99m, Cancer imaging, Enzyme targeting, Docking