Chemical characterization of polyphenols of egyptian achillea Fragrantissima with in vitro antioxidant study

dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorEissa T.F.
dc.contributor.authorGonzalez-Burgos E.
dc.contributor.authorEmilia Carretero M.
dc.contributor.authorGomez-Serranillos M.P.
dc.contributor.otherDepartment of Pharmacology
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherUniversity Complutense of Madrid
dc.contributor.otherSpain; Pharmacognosy Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherOctober University of Modern Science and Arts (MSA)
dc.contributor.otherGiza
dc.contributor.otherEgypt
dc.date.accessioned2020-01-09T20:40:57Z
dc.date.available2020-01-09T20:40:57Z
dc.date.issued2018
dc.descriptionScopus
dc.description.abstractAchillea fragrantissima (Forssk.) Sch. Bip. is one of the most popular and important medicinal plants extensively used in Egyptian folk medicine for healing different sufferings and diseases. The antioxidant properties of hydroalcoholic extract obtained from the aerial parts of A. fragrantissima were in vitro studied. The total phenolic content was 56.6 mg gallic acid equivalents/g dry weight, and the oxygen radical absorbance capacity (ORAC) was 1.127 ?mol Trolox equivalents/mg sample. The HPLC-MS identification of polyphenols revealed mainly the presence of flavones, in addition to benzoic acids, cinnamic acids, and flavonols. The hydroalcoholic extract protected human astrocytoma U373-MG cells against hydrogen peroxide-induced formation of reactive oxygen species and loss of cell viability. These findings suggest that the hydroalcoholic extract from A. fragrantissima is a natural source of antioxidant compounds that may be useful for counteracting the oxidative stress damage in central nervous system cells. � 2018, Chiang Mai University. All rights reserved.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=17800156707&tip=sid&clean=0
dc.identifier.doihttps://doi.org/
dc.identifier.issn1252526
dc.identifier.otherhttps://doi.org/
dc.identifier.urihttps://t.ly/epwMn
dc.language.isoEnglishen_US
dc.publisherChiang Mai Universityen_US
dc.relation.ispartofseriesChiang Mai Journal of Science
dc.relation.ispartofseries45
dc.subjectOctober University for Modern Sciences and Arts
dc.subjectUniversity for Modern Sciences and Arts
dc.subjectOctober University for Modern Sciences and Arts
dc.subjectMSA University
dc.subjectجامعة أكتوبر للعلوم الحديثة والآداب
dc.subjectAchillea fragrantissimaen_US
dc.subjectAntioxidant propertiesen_US
dc.subjectPolyphenolsen_US
dc.titleChemical characterization of polyphenols of egyptian achillea Fragrantissima with in vitro antioxidant studyen_US
dc.typeArticleen_US
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dcterms.sourceScopus

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