Study of DYRK1B gene expression and its association with metabolic syndrome in a small cohort of Egyptians

Simple item page
dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorMohamed, Yara Ahmed 
dc.contributor.authorHassaneen, H. M
dc.contributor.author El‑Dessouky, Mohamed A
dc.contributor.authorSafwat, Gehan 
dc.contributor.authorHassan, Naglaa Abu‑Mandil 
dc.contributor.authorAmr, Khalda 
dc.date.accessioned2021-07-25T08:15:33Z
dc.date.available2021-07-25T08:15:33Z
dc.date.issued7/21/2021
dc.description.abstractA cluster of many risk factors for type 2 diabetes and cardiovascular disease is used to describe the metabolic syndrome (MetS). Moreover, genetic differences associated with metabolic syndrome play a key role in its prevalence and side effects. This study aims to investigate the expression of DYRK1B and its association with metabolic syndrome in a small cohort of Egyptian. Materials and methods A total of 100 adult Egyptians (50 with MetS and 50 healthy control subjects) were included to this study. Clinical, biochemical and anthropometric analysis were assessed. Relative gene expressions of DYRK1B were compared between two groups of subjects using real time PCR. Results We observed marked overexpression in DYRK1B (p < 0.05) in MetS subjects when compared with the healthy control subjects. Conclusion This is the first study to provide evidence that DYRK1B is highly expressed among the MetS subjects.en_US
dc.identifier.doihttps://doi.org/10.1007/s11033-021-06560-1
dc.identifier.otherhttps://doi.org/10.1007/s11033-021-06560-1
dc.identifier.urihttps://qrgo.page.link/7dxWT
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.ispartofseriesMolecular Biology Reports;
dc.subjectMetabolic syndrome en_US
dc.subjectGene expression en_US
dc.subjectDYRK1B en_US
dc.subjectReal Time PCRen_US
dc.titleStudy of DYRK1B gene expression and its association with metabolic syndrome in a small cohort of Egyptiansen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
avatar_scholar_256.png.jpg.jpg
Size:
1.89 KB
Format:
Joint Photographic Experts Group/JPEG File Interchange Format (JFIF)
Description:
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
51 B
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Faculty of Biotechnology Research Paper