RP-HPLC determination of three anti-hyperlipidemic drugs in spiked human plasma and in dosage forms
| dc.Affiliation | October University for modern sciences and Arts (MSA) | |
| dc.contributor.author | Abdallah O.M. | |
| dc.contributor.other | Analytical Chemistry Department | |
| dc.contributor.other | Faculty of Pharmacy October | |
| dc.contributor.other | University for Modern Sciences and Arts (MSA) | |
| dc.contributor.other | El- Wahat Road | |
| dc.contributor.other | Egypt | |
| dc.date.accessioned | 2020-01-25T19:58:31Z | |
| dc.date.available | 2020-01-25T19:58:31Z | |
| dc.date.issued | 2011 | |
| dc.description | Scopus | |
| dc.description.abstract | Sensitive, simple and accurate high performance liquid chromatographic (HPLC) methods for the determination of atorvastatin (AT), fluvastatin (FL) and pravastatin (PV) have been developed. The proposed methods involve the use of a 150 mmx4.6 mm Zorbax Extend-C18 column (5 ?m particle size) and different chromatographic conditions for the separation of the three statins. Linearity range was 5-40, 5-30 and 10-60 ?g mL-1 for AT, FL and PV respectively. The developed methods proved to be successful in the determination of all studied drugs in spiked human plasma samples. | en_US |
| dc.identifier.doi | https://doi.org/10.1155/2011/376948 | |
| dc.identifier.doi | PubMed ID : | |
| dc.identifier.issn | 9734945 | |
| dc.identifier.other | https://doi.org/10.1155/2011/376948 | |
| dc.identifier.other | PubMed ID : | |
| dc.identifier.uri | https://t.ly/lWOpV | |
| dc.language.iso | English | en_US |
| dc.publisher | Hindawi Limited | en_US |
| dc.relation.ispartofseries | E-Journal of Chemistry | |
| dc.relation.ispartofseries | 8 | |
| dc.subject | Atorvastatin | en_US |
| dc.subject | Fluvastatin | en_US |
| dc.subject | HPLC | en_US |
| dc.subject | Pravastatin | en_US |
| dc.title | RP-HPLC determination of three anti-hyperlipidemic drugs in spiked human plasma and in dosage forms | en_US |
| dc.type | Article | en_US |
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| dcterms.source | Scopus |