Chemical and biological investigation of essential oil of oroxylum indicum L. Leaves cultivated in Egypt

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorZaghloul S.S.
dc.contributor.authorAzzam S.M.
dc.contributor.authorEid H.H.
dc.contributor.authorHassan H.A.
dc.contributor.authorSleem A.A.
dc.contributor.otherPharmacognosy Department
dc.contributor.otherCairo University
dc.contributor.otherCairo
dc.contributor.otherEgypt; Pharmacognosy Department
dc.contributor.otherOctober University for Modern Sciences and Arts (MSA)
dc.contributor.otherGiza
dc.contributor.otherEgypt; Pharmacology Department
dc.contributor.otherNational Research Center
dc.contributor.otherGiza
dc.contributor.otherEgypt
dc.date.accessioned2020-01-09T20:41:59Z
dc.date.available2020-01-09T20:41:59Z
dc.date.issued2015
dc.descriptionScopus
dc.description.abstractHydrodistilled essential oil of fresh leaves of Oroxylum indicum L. family Bignoniaceae cultivated in Egypt was analyzed by gas chromatography?mass spectrometry (GC/MS) .The yield of essential oil was (0.2 %) . Thirty nine components were identified representing (89.85%). Ar-tumerone (19.37%), a sesquiterpene ketone, was the major constituent in the oil followed by methyl hexadecanoate (6.2%), laurenan-2-one (5.59%) and isopropyl butanoate (5.57%). The oxygenated constituents represents (63.81 %) while non- oxygenated constituents represents (26.04 %) .The oil showed significant cytotoxic activity on MCF7 (breast carcinoma cell line), HEPG2 (liver carcinoma cell line) and HELA (cervix carcinoma cell line) ,in addition to good in vivo and in vitro antioxidant activity. The oil also exhibited both hepatoprotective and heptocurative action, but showed weak antimicrobial activity against tested bacteria with no effect against fungi. � 2015, International Journal of Pharmacognosy and Phytochemical Research. All rights reserved.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=20400195018&tip=sid&clean=0
dc.identifier.doihttps://doi.org/
dc.identifier.issn9754873
dc.identifier.otherhttps://doi.org/
dc.identifier.urihttps://t.ly/mbe7A
dc.language.isoEnglishen_US
dc.publisherInternational Journal of Pharmacognosy and Phytochemical Researchen_US
dc.relation.ispartofseriesInternational Journal of Pharmacognosy and Phytochemical Research
dc.relation.ispartofseries7
dc.subjectAntioxidanten_US
dc.subjectCytotoxicen_US
dc.subjectEssential oilen_US
dc.subjectHepatoprotective and hepatocurative activityen_US
dc.subjectOroxylum indicum Len_US
dc.subjectalanine aminotransferaseen_US
dc.subjectalkaline phosphataseen_US
dc.subjectalpha tocopherolen_US
dc.subjectamphotericin Ben_US
dc.subjectascorbic aciden_US
dc.subjectaspartate aminotransferaseen_US
dc.subjectessential oilen_US
dc.subjectsilymarinen_US
dc.subjecttetracyclineen_US
dc.subjectadulten_US
dc.subjectalanine aminotransferase blood levelen_US
dc.subjectalkaline phosphatase blood levelen_US
dc.subjectalloxan-induced diabetes mellitusen_US
dc.subjectanimal experimenten_US
dc.subjectanimal modelen_US
dc.subjectantimicrobial activityen_US
dc.subjectantineoplastic activityen_US
dc.subjectantioxidant activityen_US
dc.subjectArticleen_US
dc.subjectaspartate aminotransferase blood levelen_US
dc.subjectAspergillus nigeren_US
dc.subjectBacillus subtilisen_US
dc.subjectbreast carcinomaen_US
dc.subjectCandida albicansen_US
dc.subjectconcentration (parameters)en_US
dc.subjectconcentration responseen_US
dc.subjectcontrolled studyen_US
dc.subjectcytotoxicityen_US
dc.subjectDPPH radical scavenging assayen_US
dc.subjectdrug activityen_US
dc.subjectEgypten_US
dc.subjectEscherichia colien_US
dc.subjectHeLa cell lineen_US
dc.subjecthepatocurative activityen_US
dc.subjectHepG2 cell lineen_US
dc.subjecthydrodistillationen_US
dc.subjectin vitro studyen_US
dc.subjectin vivo studyen_US
dc.subjectliver cell carcinomaen_US
dc.subjectliver protectionen_US
dc.subjectmaleen_US
dc.subjectmass fragmentographyen_US
dc.subjectMCF 7 cell lineen_US
dc.subjectnonhumanen_US
dc.subjectOroxylumen_US
dc.subjectoxygenationen_US
dc.subjectphytochemistryen_US
dc.subjectplant leafen_US
dc.subjectPseudomonas aeruginosaen_US
dc.subjectraten_US
dc.subjectStaphylococcus aureusen_US
dc.subjectuterine cervix carcinomaen_US
dc.titleChemical and biological investigation of essential oil of oroxylum indicum L. Leaves cultivated in Egypten_US
dc.typeArticleen_US
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