New developed spectrophotometric method for simultaneous determination of salmeterol xinafoate and fluticasone propionate in bulk powder and Seritide® diskus inhalation

dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorSamir, Ahmed
dc.contributor.authorSalem, Hesham
dc.contributor.authorAbdelkawy, Mohammad
dc.date.accessioned2020-03-05T07:49:46Z
dc.date.available2020-03-05T07:49:46Z
dc.date.issued2012
dc.descriptionMSA Google Scholaren_US
dc.description.abstractA new simple, accurate, precise, rapid and economical method was developed for the simultaneous determination of Salmeterol xinafoate and Fluticasone propionate in their binary mixture in bulk powder and Seritide diskus® inhalation. The new method depends on new calculations using the mixture’s absorbance at 225 and 256.5 nm where the absorptivity of Salmeterol xinafoate is double the absorptivity of Fluticasone propionate, while the content of Salmeterol xinafoate was determined by measuring the absolute value of the first derivative ultraviolet curves at 352 nm, without interference from Fluticasone propionate. The proposed method was validated and the results obtained by adopting the proposed method were statistically analyzed and compared with those obtained by reported methods.en_US
dc.description.sponsorshipElsevieren_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=21100853576&tip=sid&clean=0
dc.identifier.citationK.P.R. Chowdary, G. Devala Rao New spectrophotometric methods for the determination of Salmeterol xinafoate Indian J Pharma Sci, 60 (1998), pp. 294-296 View Record in ScopusGoogle Scholar 2 M.S. Kondawar, R.R. Shah, J.J. Waghmare, M.K. Malusare, N.D. Shah UV spectrophotometric method for simultaneous estimation of Salmeterol xinafoate and Fluticasone propionate in bulk and dosage form Inter J Pharm Tech Res, 3 (2011), pp. 1801-1806 View Record in ScopusGoogle Scholar 3 K.P.R. Chowdary, R.G. Devala, C. Siddartha Spectrophotometric determination of salmeterol xinafoate with Folin-Ciocalteau reagent Indian Drugs, 34 (1997), pp. 606-607 View Record in ScopusGoogle Scholar 4 K. Lantider, H. Ariaya, I.M. Abdel-Maaboud HPTLC-densitometric method for simultaneous determination of salmeterol xinafoate and fluticasone propionate in dry powder inhalers Saudi Pharma J, 18 (2010), pp. 153-159 Google Scholar 5 V.G. Nayak, S.G. Belapure, C.D. Gaitonde, A.A. Sule Determination of salmeterol in metered-dose and dry-powder inhalers by reversed-phase high performance liquid chromatography J Pharma Biomed Anal, 14 (1996), pp. 511-513 ArticleDownload PDFView Record in ScopusGoogle Scholar 6 D. Murnane, G.P. Martin, C. Marriott Validation of a reverse-phase high performance liquid chromatographic method for concurrent assay of a weak base (salmeterol xinafoate) and a pharmacologically active steroid (fluticasone propionate) J Pharma Biomed Anal, 40 (2006), pp. 1149-1154 ArticleDownload PDFView Record in ScopusGoogle Scholar 7 J.C. Spencer, C. Vladimir Investigation of interaction between salmeterol and fluticasone propionate and its effect on quantitative accuracy of an LC/MS/MS assay in human plasma at low pg/mL concentrations J Chromatog B, 876 (2008), pp. 163-169 CrossRefView Record in ScopusGoogle Scholar 8 L. Minghua, Z. Lan, L. Xin, L. Qiaomei, C. Guonan, C. Zongwei A new method for the analysis of β2-agonists in human urine by pressure-assisted capillary electrochromatography coupled with electrospray ionization-mass spectrometry using a silica-based monolithic column Talanta, 81 (2006), pp. 1655-1661 Google Scholar 9 M.M. Ayad, M.M. Henawee, H.E. Abdellatef, H.M. Sayed Spectrophotometric determination of levonorgestrel, norethisterone acetate, mometasone furoate and fluticasone propionate using 4-amino-antipyrine Bull Fac Pharm Cairo Univ, 43 (2005) Google Scholar 10 N.D. Hiral, G.M. Ashlesha Rapid spectrophotometric methods for the determination of two novel steroids in bulk and pressurised metered - dose preparations Int J Pharm Health Sci, 1 (2010), pp. 68-76 Google Scholar 11 M. Kusum, k. Davinder, T. Vivek, K. Satish, S. Love Simultaneous quantitative determination of formoterol fumarate and fluticasone propionate by validated reversed-phase HPLC method in metered dose inhaler Der Pharm Sin, 6 (2011), pp. 77-84 Google Scholar 12 R.M. Byrro, I.C. César, E.S.C. de Santana A rapid and sensitive HPLC-APCI-MS/MS method determination of fluticasone in human plasma: Application for a bioequivalency study in nasal spray formulations J Pharm Biomed anal, 61 (2011), pp. 38-43 Google Scholar 13 N.D. Hiral, G.M. Ashlesha, B. Chaitanya, P. Killambi Validated HPTLC method for the determination of two novel steroids in bulk and pressurized metered-dose preparations Int J Appl Sci Eng (2011), pp. 177-185 View Record in ScopusGoogle Scholar 14 S.M. Abdelkawy, M. Amer, H.M. Lotfy, H. Zaazaa Simple spectrophotometric analysis of benzapril hydrochloride or Valsartan in combined pharmaceuticaldosages with hydrochlorothiazide Bull Fac Pharm Cairo Univ, 44 (2004), pp. 25-32 Google Scholar 15 M.R. El-Ghobashya, N.F. Abo-Talibb Spectrophotometric methods for the simultaneous determination of binary mixture of metronidazole and diloxanide furoate without prior separation J Adv Res, 1 (4) (2010), pp. 323-329 Google Scholar 16 N.D. Pandurang, R.B. Sunita Simultaneous uv spectrophotometric methods for estimation of amlodipine besilate and olmesartan medoxomil in tablet dosage form J Chem Pharma Res, 3 (2) (2011), pp. 650-656en_US
dc.identifier.doihttps://doi.org/10.1016/j.bfopcu.2012.07.006
dc.identifier.otherhttps://doi.org/10.1016/j.bfopcu.2012.07.006
dc.identifier.urihttps://t.ly/xqpwY
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesBulletin of Faculty of Pharmacy, Cairo University;Volume: 50 Issue: 2 Pages: 121-126
dc.subjectUniversity of Spectrophotometry; Isosbestic point; Salmeterol xinafoate; Fluticasone propionate; Absorptivity factor; Binary mixtureen_US
dc.titleNew developed spectrophotometric method for simultaneous determination of salmeterol xinafoate and fluticasone propionate in bulk powder and Seritide® diskus inhalationen_US
dc.typeArticleen_US

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