PREPARATION OF A MORE STABLE LYOPHILIZED BCG-T WITH THE SAME BIOPOTENTIAL FOR BLADDER CANCER IMMUNOTHERAPY

dc.Affiliation	October University for modern sciences and Arts (MSA)
dc.contributor.author	Mohamed, Aly Fahmy
dc.contributor.author	Bakkar, Ashraf
dc.contributor.author	Yahia, Mohamed
dc.contributor.author	Yasser, Menatallah
dc.date.accessioned	2019-12-31T09:24:12Z
dc.date.available	2019-12-31T09:24:12Z
dc.date.issued	4/15/2017
dc.description	MSA Google Scholar
dc.description.abstract	BCG-T is a new trend for immunotherapy of bladder cancer as an alternative to chemotherapy. The available product is liquid form of a limited stability profile. The present study aims to prepare a lyophilized form of BCG-T using different stabilizer namely Na glutamate and lactose. Stability of pharmaceutical lyophilized injection dosage form compared with the liquid form was assessed revealing that the Na glutamate and lactose stabilized BCG-T was significantly more stable than BCG-T in the liquid formula. Also, the dry weight and relative humidity and safety of both Na glutamate and lactose stabilized BCG-T were insignificantly different from the liquid form (P >0.05).	en_US
dc.identifier.uri	https://cutt.ly/BrJUbGq
dc.language.iso	en_US	en_US
dc.publisher	Inventi	en_US
dc.relation.ispartofseries	Inventi Impact - Pharm Biotech & Microbio;
dc.subject	University for CANCER IMMUNOTHERAPY	en_US
dc.subject	LYOPHILIZED BCG-T	en_US
dc.title	PREPARATION OF A MORE STABLE LYOPHILIZED BCG-T WITH THE SAME BIOPOTENTIAL FOR BLADDER CANCER IMMUNOTHERAPY	en_US
dc.type	Article	en_US

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