Advanced Approaches in Green Univariate Spectrophotometric Methods

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Date

2024-01

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Journal ISSN

Volume Title

Type

Book chapter

Publisher

wiley

Series Info

Sustainable Approaches in Pharmaceutical Sciences;Pages 157 - 2151 January 2024

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Abstract

The pharmaceutical industry and market have shown a tremendous evolution where different new pharmaceuticals and pharmaceutical combinations have been introduced in order to increase patient compliance and obtain the required outcomes. On the other hand, this evolution has raised a challenge in the field of drug analysis, where new applicable methods of analysis needed to be developed and validated to ensure that the right doses would reach patients free from any undesired compounds such as impurities, adulterants, or interfering substances that might lead to any undesirable side effects. This chapter highlights the advanced approaches in green univariate spectrophotometric methods based on basic mathematical techniques, such as subtraction, division, and multiplication, for assaying the components of multicomponent mixtures in their different pharmaceutical dosage forms utilising inexpensive, affordable, and eco-friendly facilities.

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Keywords

AGREE, Analytical GREEnness; Green analytical chemistry, GAC; Green Analytical Procedure Index, GAPI; National Environmental Methods Index NEMI; Ratio spectra

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