Impact of gamma rays on DNA quality and genetic traits in human blood samples

Abstract

This research investigates the effects of gamma rays on DNA quality and genetic traits in eight participants from Saudi Arabia (4 males and 4 females). The study aims to understand changes in genetic fingerprint sites resulting from varying levels of radiation exposure. It addresses three key research questions related to DNA quantity, obtaining complete genetic fingerprint sites, and the reliability of genetic trait results from cancer patients undergoing radiation therapy. The study's significance lies in its potential applications in forensics, medical diagnostics, and public safety, providing insights into identifying victims and perpetrators in radiation-related incidents and enhancing treatment planning for cancer patients exposed to radiation therapies. The research contributes to a broader understanding of radiation's impact on genetic material, promotes scientific knowledge, and safeguards public health. This research investigated the impact of gamma radiation on DNA quality and genetic traits in human blood samples from Saudi Arabian volunteers. Exposure to gamma radiation at doses similar to therapeutic levels used in cancer treatment was found to cause DNA fragmentation, resulting in decreased concentrations of detectable genetic loci. The study revealed that higher radiation doses had a more pronounced effect on DNA content in blood cells.