Electrochemical determination of tolfenamic acid in bulk, tablets and urine

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorAttia A.K.
dc.contributor.authorRashed N.S.
dc.contributor.authorFouad M.M.
dc.contributor.authorWasfy R.A.
dc.contributor.otherNational Organization for Drug Control and Research (NODCAR)
dc.contributor.otherCairo
dc.contributor.otherEgypt; Analytical Chemistry Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherAl-Azhar University
dc.contributor.otherCairo
dc.contributor.otherEgypt; October University for Modern Sciences and Arts (MSA)
dc.contributor.otherCairo
dc.contributor.otherEgypt
dc.date.accessioned2020-01-09T20:41:27Z
dc.date.available2020-01-09T20:41:27Z
dc.date.issued2017
dc.descriptionScopus
dc.description.abstractA simple, precise, accurate and inexpensive voltammetric method was developed for the quantitative determination of tolfenamic acid at modified glassy carbon electrode in phosphate buffer of pH 7.2. Several factors such as type of buffer, type of surfactant; scan rate and accumulation time were studied to obtain the optimum conditions for the determination of tolfenamic acid. The proposed method shows linearity in concentration range of 6.0. 10-7-6.0. 10-6 mol L-1 with mean percentage recovery of 101.2. 1.99. The limits of detection and quantification were 1.43. 10-7 mol L-1 and 4.34. 10-7 mol L-1, respectively. The proposed voltammetric method was successfully applied to determine tolfenamic acid in pharmaceutical formulations and human urine. The results of the proposed method were statistically compared with those of a reported method and showed no significant difference. Thus, it can be used as quality control for this drug in laboratories.. 2017 by CEE (Center of Excellence in Electrochemistry).en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=21100224440&tip=sid&clean=0
dc.identifier.doihttps://doi.org/
dc.identifier.issn20084226
dc.identifier.otherhttps://doi.org/
dc.identifier.urihttps://t.ly/OXr98
dc.language.isoEnglishen_US
dc.publisherCenter of Excellence in Electrochemistry, Univ. of Tehranen_US
dc.relation.ispartofseriesAnalytical and Bioanalytical Electrochemistry
dc.relation.ispartofseries9
dc.subjectModified electrodeen_US
dc.subjectPharmaceutical analysisen_US
dc.subjectTolfenamic aciden_US
dc.subjectVoltammetryen_US
dc.titleElectrochemical determination of tolfenamic acid in bulk, tablets and urineen_US
dc.typeArticleen_US
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