A new acylated flavonol from the aerial parts of Asteriscus maritimus (L.) Less (Asteraceae)
Loading...
Date
2016
Journal Title
Journal ISSN
Volume Title
Type
Article
Publisher
Taylor & Francis
Series Info
Natural product research;VOL : 30 Issue : 15
Scientific Journal Rankings
Abstract
Phytochemical investigation of the flowering aerial parts of Asteriscus maritimus (L.) Less (Asteraceae) led to the isolation of a new compound: patuletin 7-O-β-D-[(2″′S) 6″(3″′-hydroxy-2″′-methyl-propanoyl)] glucopyranoside, together with five known metabolites; β-sitosterol 2, chlorogenic acid 3, P-hydroxy -methylbenzoate 4, luteolin 5 and protocatechuic acid 6. The structures of the isolated compounds were determined by comprehensive analyses of its 1D and 2D NMR, HRMS and compared with previously known analogues. The ethanolic extract of the flowering aerial parts of A. maritimus was found to be safe (LD50 = 4.6 mg/kg) and possess significant antioxidant and anti-inflammatory activities and this was in accordance with its high phenolic content (107.36 ± 0.051 mg GAE/g extract).
Description
MSA Google Scholar
Keywords
Asteriscus Maritimus, Acylated Flavonol, Antioxidant, Anti-inflammatory