Synthesis, characterisation and biological screening of some 2-substituted benzimidazole derivatives as potential anticancer agents

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorShaaban M.A.-E.
dc.contributor.authorKamal A.M.
dc.contributor.authorTeba H.E.-S.
dc.contributor.otherPharmaceutical Organic Chemistry Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherCairo University
dc.contributor.otherCairo
dc.contributor.other11561
dc.contributor.otherEgypt; Pharmaceutical Organic Chemistry Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherOctober University for Modern Sciences and Arts (MSA)
dc.contributor.otherCairo
dc.contributor.otherEgypt
dc.date.accessioned2020-01-09T20:41:37Z
dc.date.available2020-01-09T20:41:37Z
dc.date.issued2016
dc.descriptionScopus
dc.description.abstractTwenty two new polycyclic compounds containing a 2-substituted benzimidazole core were synthesised, characterised and evaluated in vitro against the three most widespread cancers. Seven compounds showed outstanding antitumor activity towards breast, lung or central nervous system cancer cell lines.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=19700184900&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.3184/174751916X14577069096465
dc.identifier.doiPubMed ID :
dc.identifier.issn17475198
dc.identifier.otherhttps://doi.org/10.3184/174751916X14577069096465
dc.identifier.otherPubMed ID :
dc.identifier.urihttps://t.ly/MXrM3
dc.language.isoEnglishen_US
dc.publisherScience Reviews 2000 Ltden_US
dc.relation.ispartofseriesJournal of Chemical Research
dc.relation.ispartofseries40
dc.subjectOctober University for Modern Sciences and Arts
dc.subjectجامعة أكتوبر للعلوم الحديثة والآداب
dc.subjectUniversity of Modern Sciences and Arts
dc.subjectMSA University
dc.subject2-substituted benzimidazole derivativesen_US
dc.subjectAnticancer agentsen_US
dc.subjectHeterocyclic synthesisen_US
dc.subjectNucleophilic reactionsen_US
dc.titleSynthesis, characterisation and biological screening of some 2-substituted benzimidazole derivatives as potential anticancer agentsen_US
dc.typeArticleen_US
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