Screening of Lactobacillus isolates for their adherence capabilities to mammalian cells and their acid and bile tolerance

dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorAbdel-Daim A.
dc.contributor.authorHassouna N.
dc.contributor.authorHafez M.
dc.contributor.authorAshor M.S.A.
dc.contributor.authorAboulwafa M.M.
dc.contributor.otherDepartment of Microbiology and Immunology
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherModern Sciences and Arts University
dc.contributor.otherCairo
dc.contributor.otherEgypt; Department of Microbiology and Immunology
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherAin Shams University
dc.contributor.otherCairo
dc.contributor.otherEgypt; Department of Pharmaceutical Microbiology
dc.contributor.otherCollege of Pharmacy
dc.contributor.otherTaif University
dc.contributor.otherSaudi Arabia
dc.date.accessioned2020-01-25T19:58:27Z
dc.date.available2020-01-25T19:58:27Z
dc.date.issued2012
dc.descriptionScopus
dc.description.abstractBackground: Lactobacilli resemble a major part of the commensal human mucosal flora. The application of Lactobacilli as probiotics has increased during the last few years since a health promoting effect has been reported in addition to their long history of safe use. Methods and finding: In this study, fifty-two Lactobacillus isolates were recovered from dairy products or infant stools were examined in vitro for their probiotic potential. Their adherence capacities to Vero cells in addition to their acid and bile tolerance were evaluated. Only few isolates weren't able to adhere to Vero cells, while the other isolates have high to moderate adherence capacities. The majority of isolates were tolerant to acid and about 70% were tolerant to 0.3% bile salts. Conclusion: thirty two Lactobacillus isolates were found to possess desirable probiotic properties. These isolates are good candidates for further investigation in in vitro and in vivo studies for their potential health benefits and their application as novel Biotherapeutic agents. � iMedPub.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=21100225606&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.3823/260
dc.identifier.doiPubMed ID :
dc.identifier.issn19898436
dc.identifier.otherhttps://doi.org/10.3823/260
dc.identifier.otherPubMed ID :
dc.identifier.urihttps://t.ly/9Lq6l
dc.language.isoEnglishen_US
dc.relation.ispartofseriesArchives of Clinical Microbiology
dc.relation.ispartofseries3
dc.subjectAcid and bile toleranceen_US
dc.subjectAdherence to mammalian cellsen_US
dc.subjectLactobacillien_US
dc.subjectProbioticsen_US
dc.subjectLactobacillusen_US
dc.subjectMammaliaen_US
dc.titleScreening of Lactobacillus isolates for their adherence capabilities to mammalian cells and their acid and bile toleranceen_US
dc.typeArticleen_US
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