Polymorphism of FAS and FAS Ligand Genes in Alopecia Areata: A Case–control Study in Egyptian Population
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Wolters Kluwer--Medknow Publications
Series Info
Indian journal of dermatology;VOL : 63 Issue : 3
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Orcid
Abstract
Alopecia areata (AA) is a common dermatologic disease with suspected autoimmune etiology. Tumor necrosis factor superfamily member 6 or CD95 (FAS) and FAS ligand (FASL) are proapoptotic proteins. The relationship between apoptosis and autoimmunity is well recognized. Inflammatory T cells in AA are cytotoxic and possess FAS/FASL antigens
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