A comparative study of different aspects of manipulating ratio spectra applied for ternary mixtures: Derivative spectrophotometry versus wavelet transform

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorSalem H.
dc.contributor.authorLotfy H.M.
dc.contributor.authorHassan N.Y.
dc.contributor.authorEl-Zeiny M.B.
dc.contributor.authorSaleh S.S.
dc.contributor.otherAnalytical Chemistry Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherOctober University for Modern Sciences and Arts (MSA)
dc.contributor.other11787 6th October City
dc.contributor.otherEgypt; Analytical Chemistry Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherCairo University
dc.contributor.otherKasr-El Aini Street
dc.contributor.other11562 Cairo
dc.contributor.otherEgypt; Analytical Chemistry Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherModern University for Technology and Information (MTI)
dc.contributor.other12582 Al Hadaba Al Wosta
dc.contributor.otherCairo
dc.contributor.otherEgypt
dc.date.accessioned2020-01-09T20:41:54Z
dc.date.available2020-01-09T20:41:54Z
dc.date.issued2015
dc.descriptionScopus
dc.descriptionMSA Google Scholar
dc.description.abstractThis work represents a comparative study of different aspects of manipulating ratio spectra, which are: double divisor ratio spectra derivative (DR-DD), area under curve of derivative ratio (DR-AUC) and its novel approach, namely area under the curve correction method (AUCCM) applied for overlapped spectra; successive derivative of ratio spectra (SDR) and continuous wavelet transform (CWT) methods. The proposed methods represent different aspects of manipulating ratio spectra of the ternary mixture of Ofloxacin (OFX), Prednisolone acetate (PA) and Tetryzoline HCl (TZH) combined in eye drops in the presence of benzalkonium chloride as a preservative. The proposed methods were checked using laboratory-prepared mixtures and were successfully applied for the analysis of pharmaceutical formulation containing the cited drugs. The proposed methods were validated according to the ICH guidelines. A comparative study was conducted between those methods regarding simplicity, limitation and sensitivity. The obtained results were statistically compared with those obtained from the reported HPLC method, showing no significant difference with respect to accuracy and precision.� 2014 Elsevier B.V. All rights reserved.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=24530&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.1016/j.saa.2014.07.078
dc.identifier.doiPubMed ID 25171050
dc.identifier.issn13861425
dc.identifier.otherhttps://doi.org/10.1016/j.saa.2014.07.078
dc.identifier.otherPubMed ID 25171050
dc.identifier.urihttps://t.ly/w18YE
dc.language.isoEnglishen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesSpectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
dc.relation.ispartofseries135
dc.subjectOctober University for Modern Sciences and Arts
dc.subjectجامعة أكتوبر للعلوم الحديثة والآداب
dc.subjectUniversity of Modern Sciences and Arts
dc.subjectMSA University
dc.subjectArea under the curveen_US
dc.subjectDerivative of ratio spectraen_US
dc.subjectOfloxacinen_US
dc.subjectPrednisoloneen_US
dc.subjectTetryzolineen_US
dc.subjectWavelet transformen_US
dc.subjectChlorine compoundsen_US
dc.subjectMixturesen_US
dc.subjectArea under the curvesen_US
dc.subjectOfloxacinen_US
dc.subjectPrednisoloneen_US
dc.subjectRatio spectraen_US
dc.subjectTetryzolineen_US
dc.subjectWavelet transformsen_US
dc.subjecteye dropsen_US
dc.subjectimidazole derivativeen_US
dc.subjectofloxacinen_US
dc.subjectprednisoloneen_US
dc.subjectprednisolone acetateen_US
dc.subjecttetryzolineen_US
dc.subjectanalogs and derivativesen_US
dc.subjectarea under the curveen_US
dc.subjectchemistryen_US
dc.subjectcomparative studyen_US
dc.subjectproceduresen_US
dc.subjectreproducibilityen_US
dc.subjectspectrophotometryen_US
dc.subjectstandarden_US
dc.subjectwavelet analysisen_US
dc.subjectArea Under Curveen_US
dc.subjectImidazolesen_US
dc.subjectOfloxacinen_US
dc.subjectOphthalmic Solutionsen_US
dc.subjectPrednisoloneen_US
dc.subjectReference Standardsen_US
dc.subjectReproducibility of Resultsen_US
dc.subjectSpectrophotometryen_US
dc.subjectWavelet Analysisen_US
dc.titleA comparative study of different aspects of manipulating ratio spectra applied for ternary mixtures: Derivative spectrophotometry versus wavelet transformen_US
dc.typeArticleen_US
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