Characterization and comprehensive genome analysis of novel bacteriophage, vB_Kpn_ZCKp20p, with lytic and anti-biofilm potential against clinical multidrug-resistant Klebsiella pneumoniae

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dc.AffiliationOctober university for modern sciences and Arts MSA
dc.contributor.authorZaki, Bishoy Maher
dc.contributor.authorFahmy, Nada A
dc.contributor.authorAziz, Ramy Karam
dc.contributor.authorSamir, Reham
dc.contributor.authorEl-Shibiny, Ayman
dc.date.accessioned2023-01-25T11:13:22Z
dc.date.available2023-01-25T11:13:22Z
dc.date.issued2023-01
dc.description.abstractThe rise of infections by antibiotic-resistant bacterial pathogens is alarming. Among these, Klebsiella pneumoniae is a leading cause of death by hospital-acquired infections, and its multidrug-resistant strains are flagged as a global threat to human health, which necessitates finding novel antibiotics or alternative therapies. One promising therapeutic alternative is the use of virulent bacteriophages, which specifically target bacteria and coevolve with them to overcome potential resistance. Here, we aimed to discover specific bacteriophages with therapeutic potential against multiresistant K. pneumoniae clinical isolates.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=21100255109&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.3389/fcimb.2023.1077995
dc.identifier.otherhttps://doi.org/10.3389/fcimb.2023.1077995
dc.identifier.urihttp://repository.msa.edu.eg/xmlui/handle/123456789/5326
dc.language.isoen_USen_US
dc.publisherFrontiers Media S.A.en_US
dc.relation.ispartofseriesFrontiers in Cellular and Infection Microbiology;13:1077995
dc.subjectgenomeen_US
dc.subjectlyticen_US
dc.subjectanti-biofilmen_US
dc.subjectmultidrug-resistanten_US
dc.subjectKlebsiella pneumoniaeen_US
dc.titleCharacterization and comprehensive genome analysis of novel bacteriophage, vB_Kpn_ZCKp20p, with lytic and anti-biofilm potential against clinical multidrug-resistant Klebsiella pneumoniaeen_US
dc.typeArticleen_US

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