Comparative Study of the Synthetic Approaches and Biological Activities of the Bioisosteres of 1,3,4-Oxadiazoles and 1,3,4-Thiadiazoles over the Past Decade
| dc.Affiliation | October University for modern sciences and Arts (MSA) | |
| dc.contributor.author | El-Masry, Rana M | |
| dc.contributor.author | Kadry, Hanan H | |
| dc.contributor.author | Taher, Azza T | |
| dc.contributor.author | Abou-Seri, Sahar M | |
| dc.date.accessioned | 2022-05-12T08:01:41Z | |
| dc.date.available | 2022-05-12T08:01:41Z | |
| dc.date.issued | 22/04/2022 | |
| dc.description | SJR 2024 0.865 Q1 H-Index 261 | |
| dc.description.abstract | The bioisosteres of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles are well-known pharmacophores for many medicinally important drugs. Throughout the past 10 years, 1,3,4-oxa-/thiadiazole nuclei have been very attractive to researchers for drug design, synthesis, and the study of their potential activity towards a variety of diseases, including microbial and viral infections, cancer, diabetes, pain, and inflammation. This work is an up-to-date comparative study that identifies the differences between 1,3,4-thiadiazoles and 1,3,4-oxadiazoles concerning their methods of synthesis from different classes of starting compounds under various reaction conditions, as well as their biological activities and structure-activity relationship. | en_US |
| dc.description.uri | https://www.scimagojr.com/journalsearch.php?q=26370&tip=sid&clean=0 | |
| dc.identifier.citation | El-Masry, R. M., Kadry, H. H., Taher, A. T., & Abou-Seri, S. M. (2022). Comparative Study of the Synthetic Approaches and Biological Activities of the Bioisosteres of 1,3,4-Oxadiazoles and 1,3,4-Thiadiazoles over the Past Decade. Molecules, 27(9), 2709. https://doi.org/10.3390/molecules27092709 | |
| dc.identifier.doi | https://doi.org/10.3390/molecules27092709 | |
| dc.identifier.other | https://doi.org/10.3390/molecules27092709 | |
| dc.identifier.uri | http://repository.msa.edu.eg/xmlui/handle/123456789/4934 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | en_US |
| dc.relation.ispartofseries | Molecules;Volume 27, Issue 9 , May-1 2022 , Article number 2709 | |
| dc.subject | 1,3,4-oxadiazole | en_US |
| dc.subject | 1,3,4-thiadiazole | en_US |
| dc.subject | Bioisosteres | en_US |
| dc.subject | Biological activity | en_US |
| dc.subject | structure–activity relationship | en_US |
| dc.title | Comparative Study of the Synthetic Approaches and Biological Activities of the Bioisosteres of 1,3,4-Oxadiazoles and 1,3,4-Thiadiazoles over the Past Decade | en_US |
| dc.type | Article | en_US |