Preparation of Lambda-Cyhalothrin-Loaded Chitosan Nanoparticles and Their Bioactivity against Drosophila suzukii
Date
2022-09
Journal Title
Journal ISSN
Volume Title
Type
Article
Publisher
Multidisciplinary Digital Publishing Institute (MDPI)
Series Info
Nanomaterials;2022, 12, 3110.
Scientific Journal Rankings
Abstract
The encapsulation of pesticides within nanoparticles is a promising approach of advanced
technology in sustainable agriculture. Lambda-cyhalothrin (LC) was encapsulated by the ionotropic
gelation technique into chitosan (CS)/tripolyphosphate (TPP) and CS/alginate (ALG) matrixes. CS-
LC nanoparticles were characterized, and their efficacy was then evaluated against the key pest of
soft fruits in Europe and the United States, Drosophila suzukii. The encapsulation efficiency (74%),
nanoparticle yield (80%), polydispersity index (0.341), zeta potential (−23.1 mV) and particle size
(278 nm) were determined at the optimum conditions. FTIR confirmed the cross-linkage between
CS and TPP/ALG in the nanoparticles. The optimum formula recommended by the fractional
factorial design was associated with the formulation variables of CS of high or low molecular weight,
cross-linking agent (TPP), LC concentration (1.5% w/v) and stirring rate (1500 rpm), showing the
highest desirability value (0.5511). CS-LC nanoparticles of the lowest particle size (278 nm) exhibited
the highest percent mortality of D. suzukii males (86%) and females (84%), exceeding that caused
by the commercial product (Karate-zeon® 10% CS) at 2 HAT. This is the first work to use the ionic
gelation technique to make LC nanoparticles, to the best of our knowledge. The encapsulation of
chemical pesticides within biodegradable polymeric nanoparticles could be helpful for establishing
a sustainable IPM strategy with benefits for human and environmental health and the lifetime
of pesticides.
Description
Scopus
Keywords
ionotropic gelation, pyrethroids, tripolyphosphate, alginate, spotted wing drosophila