Beneficial effects of thymoquinone and omega-3 on intestinal ischemia/reperfusion-induced renal dysfunction in rats

dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorFayez, Ahmed M
dc.contributor.authorAwad, Azza S
dc.contributor.authorMona M.El-Naa, Mona M
dc.contributor.authorKenawy, Sanaa A.
dc.contributor.authorEl-Sayedc, Mostafa E.
dc.date.accessioned2019-11-02T13:50:00Z
dc.date.available2019-11-02T13:50:00Z
dc.date.issued2014-12
dc.description.abstractIntestinal ischemia–reperfusion (II/R) is a complex phenomenon causing local and remote tissue destruction and multiple-organ dysfunction. The technique has been used by many authors to produce certain organ dysfunctions. This study is to investigate the possible beneficial effects of thymoquinone and omega-3 separately in II/R-induced renal dysfunction in rats. Sixty-four Wistar albino rats were randomly allocated into four experimental groups namely sham control, II/R control, thymoquinone and omega-3 each group pre-treated separately. II/R model was established by clamping the superior mesenteric artery (SMA) for 30 min followed by 60 min reperfusion.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=21100853576&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.1016/j.bfopcu.2014.05.003
dc.identifier.otherhttps://doi.org/10.1016/j.bfopcu.2014.05.003
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1110093114000192
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesBulletin of Faculty of Pharmacy, Cairo University;Volume 52, Issue 2, December 2014, Pages 171-177
dc.subjectIntestinal ischemiaen_US
dc.subjectreperfusionen_US
dc.subjectThymoquinoneen_US
dc.subjectOmega-3en_US
dc.subjectTumor necrosis factor-αen_US
dc.subjectMyeloperoxidaseen_US
dc.titleBeneficial effects of thymoquinone and omega-3 on intestinal ischemia/reperfusion-induced renal dysfunction in ratsen_US
dc.typeArticleen_US

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