Nano-titania: a novel purification and concentration adsorbent for 125I production for medical uses
dc.Affiliation | October University for modern sciences and Arts (MSA) | |
dc.contributor.author | Sakr T.M. | |
dc.contributor.author | Fasih T.W. | |
dc.contributor.author | Amin M. | |
dc.contributor.other | Radioactive Isotopes and Generators Department | |
dc.contributor.other | Hot Laboratories Centre | |
dc.contributor.other | Atomic Energy Authority | |
dc.contributor.other | Cairo | |
dc.contributor.other | 13759 | |
dc.contributor.other | Egypt; Pharmaceutical Chemistry Department | |
dc.contributor.other | Faculty of Pharmacy | |
dc.contributor.other | October University of Modern Sciences and Arts (MSA) | |
dc.contributor.other | Giza | |
dc.contributor.other | Egypt | |
dc.date.accessioned | 2020-01-09T20:41:13Z | |
dc.date.available | 2020-01-09T20:41:13Z | |
dc.date.issued | 2017 | |
dc.description | Scopus | |
dc.description | MSA Google Scholar | |
dc.description.abstract | Abstract: The presented work describes the efficient use of nano-crystalline titania (TiO2) to remove trace levels of cesium radio-contaminants (134Cs and 137Cs) in iodine-125 (125I) solution produced via neutron activation of natural 124Xe target. The adsorption parameters of TiO2 were investigated to attain the optimum purification and concentration conditions of 125I solution. The maximum sorption capacity of Cs and 125I were approximately 56 and 67�mg/g TiO2, respectively. The final 125I solution was of high radiochemical, radionuclidic and chemical purities, besides, it showed high radioactive concentration that confirming its suitability for nuclear medicine applications and 125I brachytherapy sources preparation. Graphical abstract: [Figure not available: see fulltext.]. � 2017, Akad�miai Kiad�, Budapest, Hungary. | en_US |
dc.description.uri | https://www.scimagojr.com/journalsearch.php?q=24060&tip=sid&clean=0 | |
dc.identifier.doi | https://doi.org/10.1007/s10967-017-5439-z | |
dc.identifier.doi | PubMed ID : | |
dc.identifier.issn | 2365731 | |
dc.identifier.other | https://doi.org/10.1007/s10967-017-5439-z | |
dc.identifier.other | PubMed ID : | |
dc.identifier.uri | https://t.ly/KXMnP | |
dc.language.iso | English | en_US |
dc.publisher | Springer Netherlands | en_US |
dc.relation.ispartofseries | Journal of Radioanalytical and Nuclear Chemistry | |
dc.relation.ispartofseries | 314 | |
dc.subject | 125I | en_US |
dc.subject | 134Cs | en_US |
dc.subject | 137Cs | en_US |
dc.subject | Column chromatography | en_US |
dc.subject | Nano-titania | en_US |
dc.subject | Natural xenon | en_US |
dc.subject | Neutron activation | en_US |
dc.subject | adsorbent | en_US |
dc.subject | cesium 134 | en_US |
dc.subject | cesium 137 | en_US |
dc.subject | cesium ion | en_US |
dc.subject | iodine 125 | en_US |
dc.subject | titanium dioxide nanoparticle | en_US |
dc.subject | unclassified drug | en_US |
dc.subject | xenon | en_US |
dc.subject | xenon 124 | en_US |
dc.subject | Article | en_US |
dc.subject | brachytherapy | en_US |
dc.subject | chromatography | en_US |
dc.subject | concentration (parameters) | en_US |
dc.subject | controlled study | en_US |
dc.subject | drug purification | en_US |
dc.subject | drug quality | en_US |
dc.subject | elution | en_US |
dc.subject | gamma spectrometry | en_US |
dc.subject | neutron activation analysis | en_US |
dc.subject | nuclear medicine | en_US |
dc.subject | quality control procedures | en_US |
dc.subject | radioactive contamination | en_US |
dc.subject | radioactivity | en_US |
dc.subject | radiochemistry | en_US |
dc.title | Nano-titania: a novel purification and concentration adsorbent for 125I production for medical uses | en_US |
dc.type | Article | en_US |
dcterms.isReferencedBy | Baker, M., Bass, G.A., Woods, M.J., Calibration of the NPL secondary standard radionuclide calibrator for 125I seeds used for prostate brachytherapy (2002) Appl Radiat Isot, 56, pp. 321-325. , COI: 1:CAS:528:DC%2BD38Xht1Kg; Wallace, R.E., Model 3500 125I brachytherapy source dosimetric characterization (2002) Appl Radiat Isot, 56, pp. 581-587. , COI: 1:CAS:528:DC%2BD38XhtVSlsrw%3D; Cieszykowska, I., Piasecki, A., Mielcarski, M., An approach to the preparation of iodine-125 seed-type source (2005) Nukleonika, 50 (1), pp. 17-22. , COI: 1:CAS:528:DC%2BD2MXis1Wnt70%3D; Swidan, M.M., Sakr, T.M., Motaleb, M.A., Abd El-Bary, A., El-Kolaly, M.T., Preliminary assessment of radioiodinated fenoterol and reproterol as potential scintigraphic agents for lung imaging (2015) J Radioanal Nucl Chem, 303 (1), pp. 531-539. , COI: 1:CAS:528:DC%2BC2cXhtFyqt7bF; Sakr, T.M., Motaleb, M.A., Zaghary, W.A., Synthesis radioiodination and in vivo evaluation of ethyl 1,4-dihydro-7-iodo-4-oxoquinoline-3-carboxylate as a potential pulmonary perfusion scintigraphic radiopharmaceutical (2015) J Radioanal Nucl Chem, 303 (1), pp. 399-406. , COI: 1:CAS:528:DC%2BC2cXhtFWnsrvJ; Swidan, M.M., Sakr, T.M., Motaleb, M.A., Abd El-Bary, A., El-Kolaly, M.T., Radioiodinated acebutolol as a new highly selective radiotracer for myocardial perfusion imaging (2014) J Label Compd Radiopharm, 57, pp. 593-599. , COI: 1:CAS:528:DC%2BC2cXhsFSjs7zJ; Ibrahim, A.B., Sakr, T.M., Khoweysa, O.M.A., Motaleb, M.A., Abd El-Bary, A., El-Kolaly, M.T., Radioiodinated anastrozole and epirubicin as potential targeting radiopharmaceuticals for solid tumor imaging (2015) J Radioanal Nucl Chem, 303 (1), pp. 967-975. , COI: 1:CAS:528:DC%2BC2cXhsFShtL7I; Sakr, T.M., Synthesis and preliminary affinity testing of 123I/125I-N-(3-Iodo-phenyl)-2-methyl-pyrimidine-4,6-diamine, as a novel potential lung scintigraphic agent (2014) Radiochemistry, 56 (2), pp. 200-206. , COI: 1:CAS:528:DC%2BC2cXptVehtbY%3D; Mathew, C., Majali, M.A., Balakrishnan, S.A., A novel approach for the adsorption of iodine-125 on silver wire as matrix for brachytherapy source for the treatment of eye and prostate cancer (2002) Appl Radiat Isot, 57, pp. 359-367. , COI: 1:CAS:528:DC%2BD38XltlegtLc%3D; Wang, R., Sloboda, R.S., Monte Carlo dose parameters of the brachy Seed model LS-1125I brachytherapy source (2002) Appl Radiat Isot, 56, pp. 805-813. , COI: 1:CAS:528:DC%2BD38XjvVGiurY%3D; (2003) Manual for Reactor Produced Radioisotopes, , International Atomic Energy Agency, Vienna; Zeituni, C.A., Dosimetria de fontes de iodo-125 aplicad as embraquiterapia (2008) Ph.D, , Thesis, University of Sao Paulo; Ram, R., Chakravarty, R., Dash, A., Usefulness of nano-zirconia for purification and concentration of 125I solution for medical applications (2013) Appl Radiat Isot, 82, pp. 351-358. , COI: 1:CAS:528:DC%2BC3sXhslOktbvO; Joshi, P.V., Jagadeesan, K.C., Manolkar, R.B., Mathakar, A.R., Chirayil, V., Thkare, S.V., Dash, A., Pillai, M.R.A., Production of 125I from neutron irradiation of natural Xe gas and a wet distillation process for radiopharmaceutical applications (2012) Ind Eng Chem Res, 51, pp. 8575-8582. , COI: 1:CAS:528:DC%2BC38Xot1OksL0%3D; Chakravarty, R., Dash, A., Role of nanoporous materials in radiochemical separations for biomedical applications (2013) J Nanosci Nanotechnol, 13, pp. 2431-2450. , COI: 1:CAS:528:DC%2BC3sXmslalsbg%3D; Schmid, G., (2010) Nanoparticles: From theory to application, , Wiley, Weinheim; Chakravarty, R., Shukla, R., Tyagi, A.K., Dash, A., Separation of medically useful radioisotopes: Role of nano-sorbents (2012) Manipulation of nanoscale materials, pp. 259-301. , Ariga K, (ed), Royal Society of Chemistry Publishing, Cambridge; Chakravarty, R., Development of radionuclide generators for biomedical applications. Ph.D (2011) thesis, , Homi Bhabha National Institute, India; Borai, E.H., Breky, M.M.E., Sayed, M.S., Abo-Aly, M.M., Synthesis, characterization and application of titanium oxide nano composites for removal of radioactive cesium, cobalt and europium ions (2015) J Colloid Interface Sci, 450, pp. 17-25. , COI: 1:CAS:528:DC%2BC2MXkt1Ors74%3D; Fasih, T.W., Sakr, T.M., Ayoub, R.R., Amin, M., Preparation and evaluation of nano-crystalline titania as sorbent for 99Mo/99mTc Generator (2016) J Sep Sc Technol, 51 (13), pp. 2115-2121. , COI: 1:CAS:528:DC%2BC28XhsVykt7%2FK; Sakr, T.M., Nawar, M.F., Fasih, T.W., El-Bayoumy, S., Abd El-Rehim, H.A., Nano-technology contributions towards the development of high performance radioisotope generators: the future promise to meet the continuing clinical demand (2017) Appl Radiat Isot, 129, pp. 67-75. , COI: 1:CAS:528:DC%2BC2sXhtlCltbzJ; Mostafa, M., Motaleb, M.A., Sakr, T.M., Labeling of ceftriaxone for infective inflammation imaging using 99mTc eluted from 99Mo/99mTc generator based on zirconium molybdate (2010) Appl Radiat Isot, 68 (10), pp. 1959-1963. , COI: 1:CAS:528:DC%2BC3cXpsFSntL8%3D; Saxena, S.K., Chakravarty, R., Kumar, Y., Ram, R., Dash, A., Column chromatography using nano-sorbent viable approach towards post-processing concentration of 125I for medical applications (2013) J Sep Sc Techn, 48, pp. 2108-2114. , COI: 1:CAS:528:DC%2BC3sXisVOht7g%3D | |
dcterms.source | Scopus |