Genome sequencing reveals existence of SARS-CoV-2 B.1.1.529 variant in Egypt
| dc.Affiliation | October University for modern sciences and Arts (MSA) | |
| dc.contributor.author | Ismail, Ghada | |
| dc.contributor.author | Abdelghafar, Hossam | |
| dc.contributor.author | Seadawy, Mohamed G | |
| dc.contributor.author | Gad, Ahmed F | |
| dc.contributor.author | Ageez, Amr | |
| dc.contributor.author | ElShafei, Ahmed | |
| dc.contributor.author | Mohammed, Shereen Saeed | |
| dc.contributor.author | Ali, Marym Saied | |
| dc.contributor.author | El‑Ashry, Marwa abd El‑Rasoul | |
| dc.date.accessioned | 2022-05-22T09:43:09Z | |
| dc.date.available | 2022-05-22T09:43:09Z | |
| dc.date.issued | 2022-12 | |
| dc.description | SJR 2024 0.767 Q2 H-Index 57 | |
| dc.description.abstract | Background: Several SARS-CoV-2 variants with increased transmissibility and/or potential immune escape have emerged and rapidly spread worldwide. Ongoing surveillance analyses are performed worldwide to designate new variants of concern (VOC) of coronavirus. Main text: This report identifies the first Egyptian patient with a confirmed SARS-CoV-2 omicron variant. The patient showed positivity on reverse transcriptase-polymerase chain reaction and full genome sequencing was performed to confirm the variant. The mutations found in the variant were compared with the GISAID reference strain hCoV-19/Wuhan/WIV04/2019. Genome BLAST showed the highest similarity to omicron variants isolated in South Africa. Phylogenetic analysis revealed that the variant belongs to the 21K clade. Conclusions: The study indicates the importance of information-sharing among global public health partners. Moreover the importance of implementation of full genome sequencing to rapidly identify and track the new SARS-CoV-2 variants. | en_US |
| dc.description.uri | https://www.scimagojr.com/journalsearch.php?q=21100463067&tip=sid&clean=0 | |
| dc.identifier.citation | Ismail, G., Abdelghaffar, H., Seadawy, M. G., El-Hosseny, M. F., Gad, A. F., Ageez, A., ElShafei, A., Mohammed, S. S., Ali, M. S., & El-Ashry, M. a. E. (2022). Genome sequencing reveals existence of SARS-CoV-2 B.1.1.529 variant in Egypt. Journal of Genetic Engineering and Biotechnology, 20(1), 70. https://doi.org/10.1186/s43141-022-00352-1 | |
| dc.identifier.doi | https://doi.org/10.1186/s43141-022-00352-1 | |
| dc.identifier.other | https://doi.org/10.1186/s43141-022-00352-1 | |
| dc.identifier.uri | http://repository.msa.edu.eg/xmlui/handle/123456789/4951 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Elsevier B.V. | en_US |
| dc.relation.ispartofseries | Journal of Genetic Engineering and Biotechnology;volume 20, Article number: 70 (2022) | |
| dc.subject | Omicron variant | en_US |
| dc.subject | Egypt | en_US |
| dc.subject | 21K | en_US |
| dc.subject | genome analysis | en_US |
| dc.title | Genome sequencing reveals existence of SARS-CoV-2 B.1.1.529 variant in Egypt | en_US |
| dc.type | Article | en_US |