Chemical and Biological Investigation of Araucaria heterophylla Salisb. Resin

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorAbdel-Sattar, Essam
dc.contributor.authorR. Abdel Monem, Azza
dc.contributor.authorEzzat, Shahira M
dc.contributor.authorM. El-Halawany, Ali
dc.contributor.authorM. Mouneir, Samar
dc.date.accessioned2019-10-19T09:59:07Z
dc.date.available2019-10-19T09:59:07Z
dc.date.issued2009
dc.descriptionMSA Google Scholar
dc.description.abstractThree labdane diterpenes, namely labda-8(17),14-diene, 13-epicupressic acid, and 13-Oacetyl- 13-epicupressic acid, were isolated from the resin collected from stem exudates of Araucaria heterophylla Salisb. (Araucariaceae). The isolated compounds were identifi ed using different spectroscopic methods (1H NMR, 13C NMR, HMQC, HMBC and COSY). The resin extract showed antiulcerogenic activity against ethanol-induced stomach ulcers in Sprauge Dawely rats using ranitidine as standard. In addition, the resin and the isolated compounds showed variable cytotoxic activities against breast (MCF7) and colon (HCT116) cancer cell lines.en_US
dc.description.sponsorshipZeitschrift für Naturforschungen_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=14954&tip=sid&clean=0
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dc.identifier.doihttps://doi.org/10.1515/znc-2009-11-1211
dc.identifier.otherhttps://doi.org/
dc.identifier.urihttps://cutt.ly/htwjcEH
dc.language.isoenen_US
dc.publisherZeitschrift für Naturforschungen_US
dc.relation.ispartofseriesZ. Naturforsch.;64
dc.subjectUniversity of Araucaria heterophyllaen_US
dc.titleChemical and Biological Investigation of Araucaria heterophylla Salisb. Resinen_US
dc.typeArticleen_US

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