The impact of lncRNA-GAS5/miRNA-200/ACE2 molecular pathway on the severity of COVID-19
Date
2023-05
Journal Title
Journal ISSN
Volume Title
Type
Article
Publisher
Bentham Science Publishers B.V.
Series Info
Current Medicinal Chemistry;
Scientific Journal Rankings
Abstract
was reported to be overexpressed and its targeted ACE2 was down-regulated. The ROC curve was drawn to examine the diagnostic abilities of GAS5, miR-200, and ACE2, yielding high diagnostic accuracy with high sensitivity and specificity.
Conclusion: lncRNA-GAS5, miRNA-200, and ACE2 panels presented great diagnostic potential as they demonstrated the highest diagnostic accuracy for discriminating moderate COVID-19 and severe COVID-19 cases.
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Description
Keywords
COVID-19 patients,, miRNA-200,, ACE2,, Lnc-GAS5,, COVID-19 severity,, COVID-19 comorbidities