Recent Advances in The Synthesis of Thiazole Ring: Mini Review

Abstract

The thiazole scaffold is an essential structural foundation in a plethora of pharmaceutical products having an extensive array of biological activities. Consequently, its synthesis has been extensively discussed in the literature. In this mini review, we have summarized the recent advances of thiazole synthesis covering articles published between 2002 and 2021. We have reviewed and discussed variable recent and novel routes for the synthesis of compounds containing thiazole ring from various starting materials such as thiourea, thioamide or thiosemicarbazone. Additionally, we have illustrated environmentally benign methods for thiazole synthesis. We hope that this review can help other researchers in efficient synthesis of thiazole ring.