Nitric Oxide Regulating Proteins as Biochemical and Genetic Markers of Coronary Artery Disease
dc.Affiliation | October University for modern sciences and Arts (MSA) | |
dc.contributor.author | Z. Gad, Mohamed | |
dc.contributor.author | M. Abdel-Maksoud, Sahar | |
dc.contributor.author | I. Hassanein, Sally | |
dc.contributor.author | M. Hashad, Ingy | |
dc.contributor.author | F. Abdel Rahman, Mohamed | |
dc.contributor.author | A. Abu el Maaty, Mohamed | |
dc.contributor.author | M. Shaban, Gamal | |
dc.contributor.author | Abou-Aisha, Khaled | |
dc.date.accessioned | 2020-01-30T07:51:25Z | |
dc.date.available | 2020-01-30T07:51:25Z | |
dc.date.issued | 2016 | |
dc.description | MSA Google Scholar | en_US |
dc.description.abstract | Cardiovascular disease (CVD) remains the leading cause of death worldwide. Despite huge efforts and great advances in studying the genetic component of CVD, there is still a great need for exploring the genetic and environmental factors contributing to the development of this disease. Among these factors evolve modulation of nitric oxide (NO) homeostasis and oxidative stress as central players according to recent reports. A wide range of biochemical disturbances, including reduced bioavailability of NO and oxidative stress, has been shown to be associated with endothelial dysfunction (ED). Many studies described the contribution of ED in the predisposition of CVD, particularly coronary artery disease (CAD). Recent evidence indicates that ED may be genetically determined. This chapter points out to the key players that influence vascular NO levels and their role in the protection against and/or predisposition to CAD | en_US |
dc.description.sponsorship | Springer Netherlands | en_US |
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dc.identifier.doi | https://doi.org/10.1007/978-94-007-7741-5_34-1 | |
dc.identifier.other | https://doi.org/10.1007/978-94-007-7741-5_34-1 | |
dc.identifier.uri | https://t.ly/l8XDq | |
dc.language.iso | en | en_US |
dc.publisher | Springer Netherlands | en_US |
dc.relation.ispartofseries | Biomarkers in Cardiovascular Disease;Pages: 793-820 | |
dc.subject | University of Nitric oxide; SNP; Nitric oxide synthase; Coronary artery disease; DDAH; Paraoxonase; NADPH oxidase; Endothelin; Ox-LDL | en_US |
dc.title | Nitric Oxide Regulating Proteins as Biochemical and Genetic Markers of Coronary Artery Disease | en_US |
dc.type | Article | en_US |
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