Chemical and biological study of Mentha suaveolens Ehrh. cultivated in Egypt
| dc.Affiliation | October University for modern sciences and Arts (MSA) | |
| dc.contributor.author | Ezzat, Shahira M | |
| dc.contributor.author | A. El-Kashoury, El-Sayeda | |
| dc.contributor.author | A. Kandil, Zeinab | |
| dc.contributor.author | A. Salem, Mohamed | |
| dc.contributor.author | A. Sleem, Amany | |
| dc.date.accessioned | 2019-10-26T07:08:53Z | |
| dc.date.available | 2019-10-26T07:08:53Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | Investigation of the different fractions of the ethanolic extract of the aerial parts of M. suaveolens growing in Egypt yielded nine compounds; two new triterpenes [3β-acetyl -22α-hydroxy ursa-12,20- diene (compound 1) and 2α, 3β-dihydroxy-olean-18-en-29-oic acid (compound 7)] and nine known compounds: a sterol and its glucoside; β-sitosterol (compound 2) and β-sitosterol-3-O- β-D-glucoside (compound 4), a triterpene; oleanolic acid (compound 3), two monoterepenes; dihydrolimonene (compound 5) and 7-hydroxy-p-cymene (compound 6), two flavonoids; isoquercitrin (compound 8) and rutin (compound 9) which were isolated from M. suaveolens Ehrh. for the first time. The structures of the isolated compounds were identified by spectral data (UV, MS, 1D and 2D-NMR) and comparison with authentic samples. Moreover, the ethanolic extract showed potent analgesic activity as compared to indomethacin. The ethyl acetate fraction was the most potent as anti-inflammatory (88%), followed by the ethanolic extract (82.9%) as compared with indomethacin. The ethanolic extract and its four subfractions showed a moderate inhibitory activity against the tested human pathogenic bacteria. | en_US |
| dc.description.sponsorship | Journal of Medicinal Plant Research | en_US |
| dc.description.uri | https://www.scimagojr.com/journalsearch.php?q=19600156803&tip=sid&clean=0 | |
| dc.identifier.citation | Abbaszadeh B, Valadabadi S, Farahani H, Darvishi H (2009). Studying of essential oil variations in leaves of Mentha species. Afr. J. Plant Sci. 3:217–221. AIN (1977). Report of the American institute of nutrition ad hoc. Committee on standards for nutritional studies. J. Nutr. 107:1340-1648. El-Kashoury et al. 755 Bauer AW, Kirby WM, Sherris C, Turck M (1966). Antibiotic susceptibilty testing by a standardized single method. Am. J. Clin. Pathol. 45:493-496. Bello R, Calatayud S, Beltran B, Primo-Yufera E, Esplugues J (2001). Cardiovascular effects of the methanol and dichloromethane extracts from Mentha suaveolens Ehrh. Phytother. Res. 15:447-448. Bouic PJD, Etsebeth S, Liebenberg RW, Albrecht CF, Pegel K, Van Jaarsveld PP (1996). Human peripheral blood lymphocyte proliferation: implications for their use as an immunomodulatory vitamin combination. Int. J. Immunopharmacol. 18:693-700. Crews P, Rodriguez J, Jaspars M (1998). Organic Structure Analysis, Oxford University Press, New York. El-Kashoury EA, El-Askary HI, Kandil ZA, Salem MA, Sleem AA (2012). Chemical composition and biological activities of the essential oil of Mentha suaveolens Ehrh. Z. Naturforsch. 67c:571-579. Fang R, Jiang CH, Wang XY, Zhang HM, Liu ZL, Zhou L, Du SS, Deng ZW (2010). Insecticidal activity of essential oil of Carum carvi fruits from China and its main components against two grain storage insects. Molecules 15:9391-9402. Ferreira A, Proenca C, Serralheiro MLM, Araujo ME (2006). The in vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from Portugal. J. Ethnopharmacol. 108:31-37. Goad J, Akihisa T (1997). Analysis of Sterols. 1st edition, Blackie Academic and Professional Press, Chapman and Hall, London. Grace MH, Mohamed TK, Khattab AM (1998). Flavonoids of Carduncellus eriocephalus, Egypt. J. Pharm. Sci. 39:409-416. Hu M, Ogawa K, Sashida Y, Xiao PG (1995). Triterpenoid glucuronide saponins from root bark of Aralia armata. Phytochemistry 39:179-184. Koster R, Anderson M, De Beer E (1959). Acetic acid for analgesic screening. J. Fed. Proc. 18:412-415. Liu J (1995). Pharmacology of oleanolic acid and ursolic acid: review article. J. Ethnopharmacol. 49:57-68. López V, Martín, S. Gómez-Serranillos M, Carretero M, Jäger A, Calvo M (2010). Neuroprotective and neurochemical properties of mint extracts. Phytother. Res. 24(6):869-874. Mahatao SB, Kundu AP (1994). 13C NMR Spectra of pentacyclic triterpenoids-a compilation and some salient features: Review Article. Phytochemistry 37:1517-75. Markham KR (1982). Techniques of Flavonoid Identification; Academic Press, London. Moreno L, Bello R, Primo-Yufera E, Esplugues J (2002). Pharmacological properties of the methanol extract from Mentha suaveolens Ehrh. Phytother. Res. 16:10-13. Nakano K, Oose Y, Takaishi Y(1997). A novel epoxy-triterpene and nortriterpene from callus cultures of Tripterygium wilfordii. Phytochemistry 46:1179-1182. Shiojima K, Arai Y, Masuda K, Takase Y, Ageta T, Ageta H (1992). Mass spectra of pentacyclic triterpenoids. Chem. Pharm. Bull. 40:1683-1690 Silverstein RM, Webster FX (1996). Spectrometric identification of organic compounds, 6th Ed., John Wiley & sons, INC., New York. Tomas-Barberan FA, Husain S, Gil MI (1998). The distribution of methylated flavones in the Lamiaceae. Biochem. Syst. Ecol. 16:43-49. Vogel AJ (1975). A Textbook of Practical Organic Chemistry; 3rd ed., English Language Book Society and Longmans Group Ltd., London, pp. 969-971. Winter GA, Risley EA, Nuss GW (1962). Carrageenin-induced edema in hind paw of the rat as an assay for antiinflammatory drugs. P. Soc. Exp. Biol. Med. 111:544-547. Yang J, Guo J, Yuan J (2008). In vitro antioxidant properties of rutin. Leben.Wissen. Technol. 41:1060–1066. Zaidi F, Voirin B, Jay M, Viricelt M (1998). Free flavonoid aglycones from leaves of Mentha pulegium and Mentha suaveolens (Labiatae). Phytochemistry 48:991-994. Ziaullah KS, Bhullar SN, Warnakulasuriya HP, Rupasinghe V (2013). Biocatalytic synthesis, structural elucidation, antioxidant capacity and tyrosinase inhibition activity of long chain fatty acid acylated derivatives of phloridzin and isoquercitrin. Bioorg. Med. Chem. 21:684–692. | en_US |
| dc.identifier.doi | https://doi.org/10.5897/JMPR2014.5324 | |
| dc.identifier.issn | 1996-0875 | |
| dc.identifier.other | https://doi.org/10.5897/JMPR2014.5324 | |
| dc.identifier.uri | http://central-library.msa.edu.eg:8009/xmlui/handle/123456789/512 | |
| dc.language.iso | en | en_US |
| dc.publisher | Journal of Medicinal Plant Research | en_US |
| dc.relation.ispartofseries | Journal of Medicinal Plant Research;20 | |
| dc.subject | University of Mentha Suaveolens | en_US |
| dc.subject | Analgesic | en_US |
| dc.title | Chemical and biological study of Mentha suaveolens Ehrh. cultivated in Egypt | en_US |
| dc.type | Article | en_US |