Complement factor H polymorphism rs1061170 and the effect of cigarette smoking on the risk of lung cancer

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Date

2015

Journal Title

Journal ISSN

Volume Title

Type

Article

Publisher

Termedia Publishing

Series Info

Contemporary Oncolog;VOL : 19 ISU : 6

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Abstract

Complement factor H (CFH) has been known to inhibit the complement pathway and to contribute to tumour growth by suppressing the anti-tumour cell mediated response in cell lines from several malignancies. We examined the association of Try402His single nucleotide polymorphism in CFH gene with lung cancer and the interaction with cigarette smoking.

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Keywords

complement, factor H, Lung cancer, polymorphism, Smoking

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