Complement factor H polymorphism rs1061170 and the effect of cigarette smoking on the risk of lung cancer
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Date
2015
Journal Title
Journal ISSN
Volume Title
Type
Article
Publisher
Termedia Publishing
Series Info
Contemporary Oncolog;VOL : 19 ISU : 6
Scientific Journal Rankings
Abstract
Complement factor H (CFH) has been known to inhibit the complement pathway and to contribute to tumour growth by suppressing the anti-tumour cell mediated response in cell lines from several malignancies. We examined the association of Try402His single nucleotide polymorphism in CFH gene with lung cancer and the interaction with cigarette smoking.
Description
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Keywords
complement, factor H, Lung cancer, polymorphism, Smoking