Chemical Composition and Biological Activities of the Essential Oil from Leaves and Flowers of Pulicaria incisa sub. candolleana (Family Asteraceae)

Simple item page
dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorShahat E.A.
dc.contributor.authorBakr R.O.
dc.contributor.authorEldahshan O.A.
dc.contributor.authorAyoub N.A.
dc.contributor.otherPharmacognosy Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherOctober University for Modern Sciences and Arts (MSA)
dc.contributor.otherGiza
dc.contributor.otherEgypt; Pharmacognosy Department
dc.contributor.otherFaculty of Pharmacy
dc.contributor.otherAin Shams University
dc.contributor.otherCairo
dc.contributor.otherEgypt; Pharmacology Department
dc.contributor.otherFaculty of Medicine
dc.contributor.otherUmm Al-Qura University
dc.contributor.otherMakkah
dc.contributor.other24382
dc.contributor.otherSaudi Arabia
dc.date.accessioned2020-01-09T20:41:21Z
dc.date.available2020-01-09T20:41:21Z
dc.date.issued2017
dc.descriptionScopus
dc.description.abstractThe composition of the essential oil isolated from leaves and flowers of Pulicaria incisa sub. candolleana E. Gamal-Eldin, growing in Egypt, was analysed by GC and GC-MS. Forty-nine and 68 compounds were identified from the oils of the leaves and flowers accounting for 86.69 and 84.29%, respectively of the total detected constituents. Both leaves and flowers oils were characterized by the high content of carvotanacetone with 66.01, 50.87 and chrysanthenone 13.26, 24.3%, respectively. The cytotoxic activity of both essential oils was evaluated against hepatocellular carcinoma cell line HEPG-2, using MTT assay and vinblastine as a reference drug. Leaf oil showed higher activity with IC50 11.4�?g/ml compared with 37.4�?g/ml for flower oil. The antimicrobial activity of both oils was evaluated using agar well diffusion method towards two representatives for each of Gram positive and Gram negative bacteria as well as four representatives for fungi. The minimum inhibitory concentration of both essential oils against bacterial and fungal strains was obtained in the range of 0.49���15.63�?g/ml. � 2017 Wiley-VHCA AG, Zurich, Switzerlanden_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=130069&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.1002/cbdv.201600156
dc.identifier.doiPubMed ID 28094467
dc.identifier.issn16121872
dc.identifier.otherhttps://doi.org/10.1002/cbdv.201600156
dc.identifier.otherPubMed ID 28094467
dc.identifier.urihttps://t.ly/1VVwl
dc.language.isoEnglishen_US
dc.publisherInstitute of Physics Publishing
dc.publisherWiley-VCH Verlagen_US
dc.relation.ispartofseriesChemistry and Biodiversity
dc.relation.ispartofseries14
dc.subjectOctober University for Modern Sciences and Arts
dc.subjectUniversity for Modern Sciences and Arts
dc.subjectMSA University
dc.subjectجامعة أكتوبر للعلوم الحديثة والآداب
dc.subjectAntimicrobial activitiesen_US
dc.subjectCytotoxic activitiesen_US
dc.subjectEssential oilen_US
dc.subjectGC-MS Analysisen_US
dc.subjectPulicaria incisa sub. candolleanaen_US
dc.subject1 octen 3 olen_US
dc.subject1,2,4 trimethylbenzeneen_US
dc.subjectalpha thujeneen_US
dc.subjectamphotericin Ben_US
dc.subjectampicillinen_US
dc.subjectanetholeen_US
dc.subjectantibiotic agenten_US
dc.subjectantifungal agenten_US
dc.subjectbeta pineneen_US
dc.subjectbourboneneen_US
dc.subjectcampheneen_US
dc.subjectcarveolen_US
dc.subjectcineoleen_US
dc.subjectcopaeneen_US
dc.subjectcytotoxic agenten_US
dc.subjectessential oilen_US
dc.subjectgentamicinen_US
dc.subjecthexanalen_US
dc.subjecthexanolen_US
dc.subjecthexobarbitalen_US
dc.subjectjasmoneen_US
dc.subjectlauric aciden_US
dc.subjectpalmitic acid isopropyl esteren_US
dc.subjectpineneen_US
dc.subjectsabineneen_US
dc.subjectsesquiterpeneen_US
dc.subjectterpinen 4 olen_US
dc.subjectterpineneen_US
dc.subjectunindexed drugen_US
dc.subjectvinblastine sulfateen_US
dc.subjectantifungal agenten_US
dc.subjectantiinfective agenten_US
dc.subjectantineoplastic agenten_US
dc.subjectborane derivativeen_US
dc.subjectchrysanthenoneen_US
dc.subjectessential oilen_US
dc.subjectantibacterial activityen_US
dc.subjectantifungal activityen_US
dc.subjectArticleen_US
dc.subjectAspergillus fumigatusen_US
dc.subjectBacillien_US
dc.subjectBacillus subtilisen_US
dc.subjectbacterial strainen_US
dc.subjectCandida albicansen_US
dc.subjectchemical compositionen_US
dc.subjectcomparative studyen_US
dc.subjectconcentration responseen_US
dc.subjectcontrolled studyen_US
dc.subjectcytotoxicityen_US
dc.subjectEscherichia colien_US
dc.subjectfloweren_US
dc.subjectfungal strainen_US
dc.subjectGeotricum candidumen_US
dc.subjectHep-G2 cell lineen_US
dc.subjectIC50en_US
dc.subjectminimum inhibitory concentrationen_US
dc.subjectMTT assayen_US
dc.subjectnonhumanen_US
dc.subjectplant leafen_US
dc.subjectPseudomonas aeruginosaen_US
dc.subjectPulicariaen_US
dc.subjectPulicaria incisa sub. candolleanaen_US
dc.subjectPulicaria inuloidesen_US
dc.subjectPulicaria jaubertiien_US
dc.subjectPulicaria stephanocarpaen_US
dc.subjectStreptococcus pneumoniaeen_US
dc.subjectSyncephalastrum racemosumen_US
dc.subjectchemistryen_US
dc.subjectdrug effectsen_US
dc.subjectEgypten_US
dc.subjectfloweren_US
dc.subjectGram negative bacteriumen_US
dc.subjectGram positive bacteriumen_US
dc.subjecthumanen_US
dc.subjectisolation and purificationen_US
dc.subjectmass fragmentographyen_US
dc.subjectmicrobial sensitivity testen_US
dc.subjectplant leafen_US
dc.subjectPulicariaen_US
dc.subjectAnti-Bacterial Agentsen_US
dc.subjectAntifungal Agentsen_US
dc.subjectAntineoplastic Agentsen_US
dc.subjectBoranesen_US
dc.subjectEgypten_US
dc.subjectFlowersen_US
dc.subjectGas Chromatography-Mass Spectrometryen_US
dc.subjectGram-Negative Bacteriaen_US
dc.subjectGram-Positive Bacteriaen_US
dc.subjectHep G2 Cellsen_US
dc.subjectHumansen_US
dc.subjectMicrobial Sensitivity Testsen_US
dc.subjectOils, Volatileen_US
dc.subjectPlant Leavesen_US
dc.subjectPulicariaen_US
dc.titleChemical Composition and Biological Activities of the Essential Oil from Leaves and Flowers of Pulicaria incisa sub. candolleana (Family Asteraceae)en_US
dc.typeArticleen_US
dcterms.isReferencedByNavarro, C., Zarzuelo, A., Jim�nez, J., Duarte, J., Quevedo, J., (1989) Fitoterapia, 60, p. 277; Asghari, G., Zahabi, F., Eskandarian, A., Yousefi, H., Asghari, M., (2014) Res. J. Pharmacogn., 1, p. 27; Al-Hajj, N.Q.M., Wang, H.X., Ma, C., Lou, Z., Bashari, M., Thabit, R., (2014) Trop. J. Pharm. Res., 13, p. 1287; Hanbali, F.E., Akssira, M., Ezoubeiri, A., Gadhi, C.E.A., Mellouki, F., Benherraf, A., Blazquez, A.M., Boira, H., (2005) J. Ethnopharmacol., 99, p. 399; Ali, N.A., Sharopov, F.S., Alhaj, M., Hill, G.M., Porzel, A., Arnold, N., Setzer, W.N., Wessjohann, L., (2012) Nat. Prod. Commun., 7, p. 257; Ravandeh, M., Valizadeh, J., Noroozifar, M., Khorasani-Motlagh, M., (2011) J. Med. Plants Res., 5, p. 2035; Amer, M.M.A., Ramadan, M.F., Abd El-Gleel, W., (2007) Deut. Lebensm.-Rundsch., 103, p. 320; Mansour, R.M.A., Ahmed, A.A., Melek, F.R., Saleh, N.A.M., (1990) Fitoterapia, 61, p. 186; Saleh, N.A.M., (2003) Phytochemistry, 63, p. 239; Karim, E.I., Ishag, K.E., Elegami, A.A.B., Mahmoud, E.N., Abu-Al-Futuh, I., (1992) Fitoterapia, 63, p. 281; Ewais, E.A., Abd El-Maboud, M.M., Haggag, M.I., (2014) Rep Opin., 6, p. 27; Ramadan, M.F., Amer, M.M.A., Mansour, H.T., Wahdan, K.M., El-Sayed, R.M., El-Sanhoty, S., El-Gleel, W.A., (2009) J. Verbrauchersch. Lebensmittelsich., 4, p. 239; Boulos, L., (1995) Flora of Egypt Checklist, , Al-Hadara Publishing, Cairo; Gamal-Eldin, E., (1981) Phanerog. Monogr., 14, p. 166; Fawzy, G.A., Al Ati, H.Y., El Gamal, A.A., (2013) Pharmacogn. Mag., 9, p. 28; Al-Fatimi, M., Ali, N.A.A., Wurster, M., Al-Sokari, S.S., Lindequist, U., Setzer, W.N., (2015) World J. Pharm. Res., 4, p. 1; Cristofari, G., Znini, M., Majidi, L., Bouyanzer, A., Al-Deyab, S.S., Paolini, J., Hammouti, B., Costa, J., (2011) Int. J. Electrochem. Sci., 6, p. 6699; Algabr, M.N., Ameddah, S., Menad, A., Mekkiou, R., Chalchat, J.-C., Benayache, S., Benayache, F., (2012) Int. J. Med. Arom. Plants, 2, p. 688; El-Kamali, H.H., Yousif, M.O., Ahmed, O.I., Sabir, S.S., (2009) Ethnobot. Leaflets, 13, p. 467; Chhetri, B.K., Ali, N.A.A., Setzer, W.N., (2015) Medicines, 2, p. 67; Adams, R.P., (2007) Identification of Essential Oils Components by Gas Chromatography/Mass Spectrometry, , 4th edn, Allured Publishing Corporation, USA; Wilson, A.P., Cytotoxicity and viability assays (2000) Animal Cell Culture: A Practical Approach, , �, in �, 3rd edn, Ed., J. R. W Masters, Oxford University Press; Saini, R.K., Choudary, A.S., Joshi, Y.C., Joshi, P., (2005) E�J. Chem., 2, p. 224
dcterms.sourceScopus

Files

Original bundle

Now showing 1 - 2 of 2
Thumbnail Image
Name:
avatar_scholar_256.png
Size:
6.31 KB
Format:
Portable Network Graphics
Description:
Download
Thumbnail Image
Name:
Antimicrobialpaper.pdf
Size:
849.03 KB
Format:
Adobe Portable Document Format
Description:
Download

Collections

Faculty Of Pharmacy Research Paper