Faculty Of Biotechnology Graduation Project 2017 - 2018

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Antioxidant, antimicrobial and anticancer effect of Beta vulgaris
(October University for Modern Sciences and Arts, 2018) Megahed Hamed, Basma
Origin of Beta vulgaris (the beet) was first reported domestically in Ancient Mesopotamia, 8th century B.C. was when the first written documents started appearing about Beta vulgaris (Smulders et al., 2010). Beetroots (Beta vulgaris) have many medical uses and its health promoting and disease preventing functional food. Beetroot is also being considered as a promising therapeutic treatment in a range of clinical pathologies associated with oxidative stress and inflammation. It was demonstrated that the phenolic compounds found in beetroots have many biological activities such as antimicrobial, anti-inflammatory, anti-diabetic, antioxidant and anticancer activity The present study is to investigate the in vitro antioxidant, antimicrobial and anticancer activity of flavonoids, phenols, alkaloids and tannins extract from beetroot. The extraction done by ethanolic extraction method to extract the phenolic compounds from beetroot. The phytochemical analysis was determined by HPLC analysis, Antioxidant activity was evaluated by DPPH while antimicrobial activity was determined by agar disc diffusion method. The cytotoxic activity was tested by using two different human cell lines which are human lung cancer (A549) and colorectal adenocarcinoma Caco-2 (colon cancer), and the cytotoxicity was tested by the neutral red (NR). assay.