Faculty of Biotechnology Research Paper

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Browsing Faculty of Biotechnology Research Paper by Author "26 July Mehwar Road intersection with Wahat Road"

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    Antimicrobial activity of hybrids terpolymers based on magnetite hydrogel nanocomposites
    (MDPI AG, 2019) Farag R.K.; Labena A.; Fakhry S.H.; Safwat G.; Diab A.; Atta A.M.; Petroleum Application Department; Egyptian Petroleum Research Institute (EPRI); Nasr City; Cairo; 11727; Egypt; Faculty of Biotechnology; October University for Modern Science and Arts; 26 July Mehwar Road intersection with Wahat Road; 6th October City P.O. Box 2511; Egypt; Chemistry Department; College of Science; King Saud University; P.O. Box 2455; Riyadh; 11451; Saudi Arabia
    In the past few years, the development of hydrogel properties has led to the emergence of nanocomposite hydrogels that have unique properties that allow them to be used in various different fields and applications such as drug delivery, adsorption soil containing, tissue engineering, wound dressing, and especially antimicrobial applications. Thus, this study was conducted in order to fabricate a novel crosslinked terpolymer nanocomposite hydrogel using the free radical copolymerization method based on the usage of 2-acrylamido-2-methylpropane sulfonic acid (AMPS), acrylamide (AAm), acrylonitrile (AN), and acrylic acid (AA) monomers and iron oxide (Fe3O4) magnetic nanoparticles and using benzoyl peroxide as an initiator and ethylene glycol dimethacrylate (EGDMA) as a crosslinker. The structure of the synthesized composite was confirmed using Fourier transform infrared (FTIR) spectroscopy and x-ray powder diffraction (XRD) measurements. Furthermore, the surface morphology and the magnetic nanoparticle distributions were determined by scanning electron microscopy (SEM) measurement. In addition, the swelling capacity of the hydrogel nanocomposite was measured using the swelling test. Lastly, the efficiency of the produced composite was evaluated as an antimicrobial agent for Gram-positive and Gram-negative bacterial strains and a fungal strain. � 2019 by the authors.