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Browsing Faculty Of Pharmacy Research Paper by Author "Faculty of Medicine"

Now showing items 1-20 of 37

Assessment of Cryptosporidium parvum infection in immunocompetent and immunocompromised mice and its role in triggering intestinal dysplasia

Abdou A.G.; Harba N.M.; Afifi A.F.; Elnaidany N.F. (Elsevier B.V., 2013)

Objectives: There is an association between chronic inflammation and cancer, including colon cancer. Cryptosporidium parvum is a protozoan parasite that infects the gastrointestinal epithelial cells causing several ...
Association of manganese superoxide dismutase Ala16Val polymorphism in the incidence of acute myocardial infarction in the Egyptians

Abdelrauf L.M.; Abdel Rahman M.F.; Abdel-Maksoud S.M.; Farag N.M.; Hashad I.M. (Academy of Scientific Research and Technology, 2017)

Background: Oxidative stress has been implicated in various diseases including atherosclerosis; the most common pathologic process underlying acute myocardial infarction (AMI). The manganese superoxide dismutase (MnSOD) ...
Association of serum level of Vitamin D and VDR polymorphism Fok1 with the risk or survival of pancreatic cancer in Egyptian population

Mohamed A.; Aref A.; Talima S.; A Elshimy R.; Gerges S.; Meghed M.; Zahran F.; El-Adawy E.; Abd-Elsalam S. (Wolters Kluwer Medknow Publications, 2019)

BACKGROUND AND AIMS: Pancreatic cancer (PC) is the fourth most common cause of death from cancer in Egypt. Few studies have been conducted to assess the relationship between vitamin D serum level and vitamin D receptor ...
C(-260)T polymorphism in CD14 receptor gene of Egyptians with acute myocardial infarction

Hashad I.M.; Hossni N.M.; Abdel Rahman M.F.; Shehata M.; Shaban G.; Gad M.Z. (Bentham Science Publishers B.V., 2018)

Background: Despite the significance of the traditional risk factors, recently published studies have suggested that inflammatory processes and variations in the genetics of the inflammatory system may participate in the ...
Carbapenem-resistant Gram-negative bacteria associated with catheter-related bloodstream infections in three intensive care units in Egypt

Abdulall A.K.; Tawfick M.M.; El Manakhly A.R.; El Kholy A. (IEEE Computer SocietySpringer Verlag, 2018)

We aimed to identify the carbapenem-resistant Gram-negative bacteria (GNB) causing catheter-related bloodstream infections (CRBSI) in intensive care units (ICU) in a tertiary care Egyptian hospital, to study their resistance ...
Cathepsin D expression in chronic plaque psoriasis: An immunohistochemical study

Abdou A.G.; Maraee A.H.; Shoeib M.A.E.; Elsammie A.A.A.; Elnaidany N.F. (2011)

Cathepsins are lysosomal cysteine proteases, which are involved in a variety of physiologic processes such as proenzyme activation, antigen presentation, tissue remodeling, bone matrix resorption, and pathologic processes ...
Chemical Composition and Biological Activities of the Essential Oil from Leaves and Flowers of Pulicaria incisa sub. candolleana (Family Asteraceae)

Shahat E.A.; Bakr R.O.; Eldahshan O.A.; Ayoub N.A. (Institute of Physics PublishingWiley-VCH Verlag, 2017)

The composition of the essential oil isolated from leaves and flowers of Pulicaria incisa sub. candolleana E. Gamal-Eldin, growing in Egypt, was analysed by GC and GC-MS. Forty-nine and 68 compounds were identified from ...
Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway.

Saleh D.O.; Mansour D.F.; Hashad I.M.; Bakeer R.M. (Elsevier B.V., 2019)

Aging; a biological phenomenon characterized by progressive decline in cellular functions, is considered as a major risk factor of various liver diseases that plays as an adverse prognostic role, thus increasing mortality ...
Epidemiology of dermatophyte infections among school children in Menoufia Governorate, Egypt

Farag A.G.A.; Hammam M.A.; Ibrahem R.A.; Mahfouz R.Z.; Elnaidany N.F.; Qutubuddin M.; Tolba R.R.E. (Blackwell Publishing Ltd, 2018)

Most superficial mycotic infections of human skin are due to dermatophytes. Children are frequently affected due to different predisposing factors, particularly overcrowding in classrooms. This study aimed to estimate the ...
Evaluation of the effect and mechanism of action of local phenytoin in treatment of vitiligo

Abdou A.G.; Abdelwahed Gaber M.; Elnaidany N.F.; Elnagar A. (Taylor and Francis Inc., 2017)

There are many theories explaining vitiligo such as genetic, autoimmune, neural, free radicals, biochemical, intrinsic defect, melanocytorrhagy, and convergent theories. Phenytoin is a widely used anticonvulsant, which is ...
Formulation and Clinical Efficacy of Myrrh Extract in Hard Gelatin Capsules

Hashem F.M.; Massoud A.M.A.; Melokheya A.M.; Emad H.; Abd El-Fattah Badr K.; Dawoud M. (Taylor and Francis Ltd., 2013)

The development of myrrh extract from natural origin capable of eradication of schistosomal infections has gained the interest of many scientists. Recently; myrrh extract is considered as the drug of choice from natural ...
Helicobacter pylori infection in patients with chronic urticaria: Correlation with pathologic findings in gastric biopsies

Abdou A.G.; Elshayeb E.I.; Farag A.G.A.; Elnaidany N.F. (2009)

Background: Chronic urticaria is a persistent urticaria lasting longer than 6.weeks, affecting 20% of the general population. Various infectious agents have been reported as causes of urticaria, including Helicobacter ...
IL-10 and TGF-?: Roles in chondroprotective effects of Glucosamine in experimental Osteoarthritis?

Waly N.E.; Refaiy A.; Aborehab N.M. (Elsevier B.V., 2017)

Objective Osteoarthritis (OA) is a complex disease of the whole joint. Glucosamine (GlcN) treatment may have a chondroprotective effect on OA. We investigated the mechanism of action of glucosamine treatment through ...
IL-6 and NFE2L2: A putative role for the hepatoprotective effect of N. Sativa, P. Ginseng and C. Sempervirens in AFB-1 induced hepatocellular carcinoma in rats

Aborehab N.M.; Waly N.E. (Elsevier Inc., 2019)

In this study, we investigated possible hepato-protective effects of N. Sativa, P. Ginseng, and C. Sempervirens in Aflatoxin B1 (AFB-1) induced hepatocellular carcinoma rat model. Fifty-four male albino rats were randomly ...
IL-8 mRNA and serum levels in vitiligo patients: A case control study

Farag A.G.; Marae A.H.; Habib M.S.E.; Mahfouz R.Z.; Elnaidany N.F.; Youssef S.I.; El-Feky S.M. (Oxford University PressJournal of Clinical and Diagnostic Research, 2017)

Introduction: Many theories are suggested to explain aetiology of vitiligo, such as autoimmune, genetic and biochemical. Interleukin-8 (IL-8) is a pro-inflammatory chemokine which is evaluated in the pathogenesis of some ...
Immunohistochemical expression of ezrin in cutaneous basal and squamous cell carcinomas

Abdou A.G.; Maraee A.H.; El-Sayed E.M.M.; Elnaidany N.F. (2011)

Ezrin is a member of the ezrin-radixin-moesin family of proteins, which link the actin-containing cytoskeleton to the plasma membrane. Overexpression of ezrin protein is correlated with the metastatic potential in several ...
Immunohistochemical expression of leptin in non melanoma skin cancer

Farag A.G.A.; Elnaidany N.F.; El-Dien M.M.S. (Journal of Clinical and Diagnostic Research, 2016)

Introduction: Obesity in adults is associated with numerous health disorders including some forms of cancer. Various epidemiological studies have found a link between excess adiposity and malignant melanoma; however, the ...
In-vivo antioxidant and anti-inflammatory activity of rosiglitazone, a peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonists in animal model of bronchial asthma.

El-Naa M.M.; El-Refaei M.F.; Nasif W.A.; Abduljawad S.H.; El-Brairy A.I.; El-Readi M.Z. (Blackwell Publishing Ltd, 2015)

Objectives Peroxisome proliferator activated receptor-gamma (PPAR-?) has been shown to play an important role in the control of immunological and inflammatory responses. This study aims at investigating the potential role ...
Is Vitamin D a participant in narrow-band ultraviolet B-induced pigmentation in patients with vitiligo?

Farag A.G.A.; Haggag M.M.; Muharram N.M.; Mahfouz R.; Elnaidany N.F.; Abd El Ghany H.M. (Lippincott Williams and Wilkins, 2018)

Background Because of its safety and efficacy, narrow-band ultraviolet B (NBUVB) therapy has found importance in vitiligo treatment. NBUVB may promote pigmentation in vitiligo through provoked vitamin D synthesis. However, ...
Macrophage migration inhibitory factor as an incriminating agent in vitiligo

Farag A.G.A.; Habib M.S.; Kamh M.E.; Hammam M.A.; Elnaidany N.F. (Sociedade Brasileira de Dermatologia, 2018)

Background: Vitiligo is an autoimmune skin disorder in which the loss of melanocytes is mainly attributed to defective autoimmune mechanisms and, lately, there has been more emphasis on autoinflammatory mediators. Among ...

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