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Browsing Faculty Of Pharmacy Research Paper by Author "Cairo University"

Now showing items 1-20 of 174

5-Fluorouracil induces plasmonic coupling in gold nanospheres: New generation of chemotherapeutic agents

Mohamed M.B.; Adbel-Ghani N.T.; El-Borady O.M.; El-Sayed M.A. (2012)

Loading 5- Fluorouracil (5-FU) into gold nanoparticles (AuNPs) could enhance its activity as anticancer drug hugely by enhancing its ability for penetration through the cell membrane. Accordingly, this work is devoted to ...
Acovenoside A Induces Mitotic Catastrophe Followed by Apoptosis in Non-Small-Cell Lung Cancer Cells

El Gaafary M.; Ezzat, Shahira M; El Sayed A.M.; Sabry O.M.; Hafner S.; Lang S.; Schmiech M.; Syrovets T.; Simmet T. (American Chemical Society, 2017)

We investigated the cytotoxic potential of the cardenolide glycoside acovenoside A against non-small-cell lung cancer cells. Lung cancer is the leading cause of cancer-related mortality and the second most common cancer ...
Advanced approaches for the treatment and amplification of weak spectral signals produced by critical concentrations in white multicomponent systems

Lotfy H.M.; Saleh S.S.; El-Maraghy C.M. (Elsevier B.V., 2020)

An analytical investigation was carried out to study the treatment and amplification of the spectral signals produced by critical concentrations with high accuracy and precision using two advanced approaches. The ...
Anti-Alzheimer potential, metabolomic profiling and molecular docking of green synthesized silver nanoparticles of Lampranthus coccineus and Malephora lutea aqueous extracts

Youssif K.A.; Haggag E.G.; Elshamy A.M.; Rabeh M.A.; Gabr N.M.; Seleem A.; Alaraby Salem M.; Hussein A.S.; Krischke M.; Mueller M.J.; Abdelmohsen U.R. (Public Library of Science, 2019)

The green synthesis of silver nanoparticles (SNPs) using plant extracts is an eco-friendly method. It is a single step and offers several advantages such as time reducing, cost-effective and environmental non-toxic. Silver ...
Anti-tumor and anti-leishmanial evaluations of 1,3,4-oxadiazine, pyran derivatives derived from cross-coupling reactions of ?-bromo-6H-1,3,4- oxadiazine derivatives

Mohareb R.M.; Schatz J. (2011)

Cyanoacetylhydrazine reacted with the ?-bromoacetophenones 2a,b to give hydrazide-hydrazone derivatives 3a,b. The latter products were cyclized to the 1,3,4-oxadiazine derivatives 4a,b. Bromination of the latter products ...
Anticancer potentiality of lignan rich fraction of six Flaxseed cultivars

Ezzat, Shahira M; Shouman S.A.; Elkhoely A.; Attia Y.M.; Elsesy M.S.; El Senousy A.S.; Choucry M.A.; El Gayed S.H.; El Sayed A.A.; Sattar E.A.; El Tanbouly N. (Nature Publishing Group, 2018)

The objective of our study is to highlight the therapeutic effect and mechanism of action by which purified Flaxseed hydrolysate (PFH) which is a lignan rich fraction exerts its anticancer activity on a human breast cancer ...
Antidepressant-Like Effect of Selected Egyptian Cultivars of Flaxseed Oil on a Rodent Model of Postpartum Depression

El Tanbouly N.; El Sayed A.M.; Ali Z.Y.; Abdel Wahab S.; El Gayed S.H.; Ezzat, Shahira M; El Senousy A.S.; Choucry M.A.; Abdel-Sattar E. (Hindawi Limited, 2017)

Flaxseed (Linum usitatissimum L.) is a multipurpose crop with health promoting potential. This study was undertaken to investigate the fatty acid profile and yield of fixed oil of six Egyptian flaxseed cultivars. The ...
Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study

El-Lakkany N.M.; El-Maadawy W.H.; Seif el-Din S.H.; Saleh S.; Safar M.M.; Ezzat, Shahira M; Mohamed S.H.; Botros S.S.; Demerdash Z.; Hammam O.A. (National Taiwan University, 2019)

Few studies reported the antifibrotic effects of gallic acid (GA) despite its known hepatoprotective and antioxidant activities. Accordingly, this study investigated the antifibrotic effects of GA through clarifying its ...
Antimicrobial activities against biofilm formed by Proteus mirabilis isolates from wound and urinary tract infections

Wasfi R.; Abd El-Rahman O.A.; Mansour L.E.; Hanora A.S.; Hashem A.M.; Ashour M.S. (2012)

Background: Bacterial species are capable of living as biofilm and/or planktonic forms. There is increasing evidence for the role of bacterial biofilm in various wound and urinary tract infections (UTIs). The aim of the ...
Antimicrobial resistance pattern and their beta-lactamase encoding genes among Pseudomonas aeruginosa strains isolated from cancer patients

Zafer M.M.; Al-Agamy M.H.; El-Mahallawy H.A.; Amin M.A.; Ashour M.S.E.-D. (2014)

This study was designed to investigate the prevalence of metallo-?-lactamases (MBL) and extended-spectrum ?-lactamases (ESBL) in P. aeruginosa isolates collected from two different hospitals in Cairo, Egypt. Antibiotic ...
Antioxidant activity and molecular docking study of Erythrin neillii polyphenolics

Gabr S.K.; Bakr R.O.; Mostafa E.S.; El-Fishawy A.M.; El-Alfy T.S. (Elsevier B.V., 2019)

Species of genus Erythrina have a great contribution in folk medicine; various species are utilized as a tranquilizer, to treat insomnia, inflammation and colic. Besides, Erythrina species have reported antioxidant, ...
Antiviral potential of green synthesized silver nanoparticles of lampranthus coccineus and malephora lutea

Haggag E.G.; Elshamy A.M.; Rabeh M.A.; Gabr N.M.; Salem M.; Youssif K.A.; Samir A.; Bin Muhsinah A.; Alsayari A.; Abdelmohsen U.R. (Dove Medical Press Ltd., 2019)

Background: Viral and microbial infections constitute one of the most important life-threatening problems. The emergence of new viral and bacterial infectious diseases increases the demand for new therapeutic drugs. Purpose: ...
Association of polymorphism in adiponectin (+45 T/G) and leptin (-2548 G/A) genes with type 2 diabetes mellitus in male Egyptians

Motawi T.; Salman T.; Shaker O.; Abdelhamid A. (Termedia Publishing House Ltd., 2015)

Introduction: Adiponectin is an adipose tissue-specific protein with insulin- sensitizing properties. Many investigators have explored the association between adiponectin single nucleotide polymorphisms (SNPs) and type 2 ...
Association of serum level of Vitamin D and VDR polymorphism Fok1 with the risk or survival of pancreatic cancer in Egyptian population

Mohamed A.; Aref A.; Talima S.; A Elshimy R.; Gerges S.; Meghed M.; Zahran F.; El-Adawy E.; Abd-Elsalam S. (Wolters Kluwer Medknow Publications, 2019)

BACKGROUND AND AIMS: Pancreatic cancer (PC) is the fourth most common cause of death from cancer in Egypt. Few studies have been conducted to assess the relationship between vitamin D serum level and vitamin D receptor ...
Athyrium plants - Review on phytopharmacy properties

Salehi B.; Ezzat, Shahira M; Tsouh Fokou P.V.; Albayrak S.; Vlaisavljevic S.; Sharifi-Rad M.; Bhatt I.D.; Sharifi-Rad M.; Belwal T.; Ayatollahi S.A.; Kobarfard F.; Ata A.; Baghalpour N.; Martorell M.; Setzer W.N.; Sharifi-Rad J. (National Taiwan University, 2019)

Athyrium plants consist of more than 230 species that are largely distributed in the Sino-Himalayan region and the Western Pacific islands. Athyrium species are being used in traditional medicine worldwide to treat various ...
Bioactive glycoalkaloides isolated from Solanum melongena fruit peels with potential anticancer properties against hepatocellular carcinoma cells

Fekry M.I.; Ezzat, Shahira M; Salama M.M.; Alshehri O.Y.; Al-Abd A.M. (Nature Publishing Group, 2019)

Hepatocellular carcinoma (HCC) is progressively increasing tumor with lack of accurate prognosis and inadequate systemic treatment approaches. Solanum sp. (such as Solanum melongena) is a folk herb which is reported to ...
Biofilm formation in enterococci: Genotype-phenotype correlations and inhibition by vancomycin

Hashem Y.A.; Amin H.M.; Essam T.M.; Yassin A.S.; Aziz R.K. (Nature Publishing Group, 2017)

Enterococci are nosocomial pathogens that can form biofilms, which contribute to their virulence and antibiotic resistance. Although many genes involved in biofilm formation have been defined, their distribution among ...
Biomonitoring detoxification efficiency of an algal-bacterial microcosm system for treatment of coking wastewater: Harmonization between Chlorella vulgaris microalgae and wastewater microbiome

Hassan M.; Essam T.; Mira A.; Megahed S. (Elsevier B.V., 2019)

Nowadays, due to worldwide water shortage, water utilities are forced to re-evaluate treated wastewater. Consequently, wastewater treatment plants need to conduct biomonitoring. Coking wastewater (CWW) has toxic, mutative ...
Botanical and genetic characters of Erythrina neillii cultivated in Egypt

Gabr S.K.; Bakr R.O.; Elshishtawy H.M.; El-Fishawy A.M.; El-Alfy T.S. (Sociedade Brasileira de Farmacognosia, 2017)

Erythrina neillii Mabberley & Lorence, Fabaceae, is a sterile hybrid between E. herbacea L. and E. humeana Spreng. Nothing was traced about its genetic, macro and micromorphology. Therefore, it was deemed of interest to ...
Brain Cortical and Hippocampal Dopamine: A New Mechanistic Approach for Eurycoma longifolia Well-Known Aphrodisiac Activity and Its Chemical Characterization

Ezzat, Shahira M; Ezzat M.I.; Okba M.M.; Hassan S.M.; Alkorashy A.I.; Karar M.M.; Ahmed S.H.; Mohamed S.O.; Fernandes G. (Hindawi Limited, 2019)

Eurycoma longifolia Jack (Fam.: Simaroubaceae), known as Tongkat Ali (TA), has been known as a symbol of virility and sexual power for men. Metabolic profiling of the aqueous extract of E. longifolia (AEEL) using UPLC-MS/MS ...

Now showing items 1-20 of 174

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Browsing Faculty Of Pharmacy Research Paper by Author "Cairo University"

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