Remineralization Potential Of Pearl Powder Compared To Casein Phosphopeptide Amorphous Calcium Phosphate On Enamel White Spot Lesions (Randomized Clinical Trial)

Abstract

Aim: The aim of this study was to evaluate the remineralization potential of pearl powder on early (‘white spot’) lesions in enamel compared to casein phosphopeptide-amorphous calcium phosphate . Methodology: Twenty Patients who had post orthodontic white spot lesions (57 subjects) were included and were randomly allocated in two groups receiving either CPP-ACP as a control (29 subjects) or pearl powder gel (28 subjects), they used it twice daily for three months. The white spot lesions were assessed clinically at baseline, 3,6,9 and 12 months using the Clinical index used for visual evaluation of white spot lesions and photographic image analysis to detect the change in color and area of the white spot lesions. Parametric data were analyzed for intergroup comparisons using independent t-test and for intragroup comparisons using repeated measures ANOVA followed by Bonferroni post hoc test. Non-parametric data were analyzed using Mann-Whitney U test for intergroup comparisons and Friedman’s test followed by Nemenyi post hoc test for intragroup comparisons. The significance level was set at p≤0.05 within all tests. Results: A significant improvement of the clinical WSL-scores was found over time in both groups, with no statistically significant difference (p<0.01). As for the photographic image analysis, the color change and area of WSLs significantly improved after12 months with no statistical difference observed between both groups. Conclusions: The Pearl powder had a similar remineralization potential when compared to CPP-ACP on the early enamel white spot lesions after 12 .months