Browsing by Author "Sharifi-Rad, Mehdi"

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    Rosmarinus plants: Key farm concepts towards food applications
    (wiley online library, 2020-01) Sharifi-Rad, Javad; Ezzat, Shahira M; El Bishbishy, Mahitab H.; Mnayer, Dima; Sharopov, Farukh; Kılıç, Ceyda S.; Neagu, Monica; Constantin, Carolina; Sharifi-Rad, Mehdi; Atanassova, Maria Maria; Nicola, Silvana; Pignata, Giuseppe; Salehi, Bahare; Fokou, Patrick Valere Tsouh; Martins, Natália
    Rosmarinus species are aromatic plants that mainly grow in the Mediterranean region. They are widely used in folk medicine, food, and flavor industries and represent a valuable source of biologically active compounds (e.g., terpenoids, flavonoids, and phenolic acids). The extraction of rosemary essential oil is being done using three main methods: carbon dioxide supercritical extraction, steam distillation, and hydrodistillation. Furthermore, interesting antioxidant, antibacterial, antifungal, antileishmanial, anthelmintic, anticancer, anti-inflammatory, antidepressant, and antiamnesic effects have also been broadly recognized for rosemary plant extracts. Thus the present review summarized data on economically important Rosmarinus off- icinalis species, including isolation, extraction techniques, chemical composition, phar- maceutical, and food applications.
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    Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health
    (American Chemical Society, 5/14/2020) Salehi, Bahare; Machin, Laura,; Monzote, Lianet; Sharifi-Rad, Javad,; Ezzat, Shahira M; Salem, Mohamed A.; Merghany, Rana M. ,; . El Mahdy, Nihal M,; Sibel Kılıc, Ceyda ,; Sytar, Oksana; Sharifi-Rad, Mehdi; Sharopov, Farukh; Martins, Natalia,; Martorell, Miquel,; Cho, William C
    Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que. © Copyright © 2020 American Chemical Society.