Browsing by Author "Bayoumi, Faten S."

Filter results by typing the first few letters
Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    Antimicrobial potential of Mentha Spp. essential oils as raw and loaded solid lipid nanoparticles against dental caries
    (rjpt, 2020-09) Mostafa, Dalia A; Bayoumi, Faten S.; Taher, Heba M.; Abdelmonem, Basma H.; Eissa, Tarek F.
    This study evaluates the antimicrobial potential of Mentha spp. (M.spicata L.,M. xpiperita L. and M. pulegium L.) essential oils as raw and loaded solid lipid nanoparticles (SLNs)against dental caries. Design: Essentials oils extraction from fresh aerial parts of Mentha spp. was carried out using hydro distillation technique. Solid lipid nanoparticles of Mentha essential oil were prepared by w/o/w type double emulsification method. The antimicrobial activity of both pure Mentha spp. essential oils and Mentha spp. SLNs was determined against bacteria presented in saliva collected from 12 patients using agar diffusion assay. Results: Mentha spp. essential oils loaded solid lipid nanoparticles (MSLNs) were spherical shaped with sizes ranged from 111 to 202 nm and with PDI from 0.43 to 0.76, EE% between 85 and 88, and ZP of −11.8 to -40 mV. Antimicrobial results showed that MSLNs exhibited higher in vitro antimicrobial activity than pure Mentha spp. essential oil. Particularly, with an inhibition zone of 20 mm. These both MSLNs were even more active than the reference compound novobiocin. Conclusion: Our findings demonstrate that Mentha spp. essential oils as a nanostructure increase the efficiency of these natural products as antibacterial agents against caries.
  • Thumbnail Image
    Item
    Characterization of Some Enteroviruses in Irrigating Water of Rural and Urban Areas in Egypt and in Clinical Samples with the Assessment of Ethanolic Extract of Nigella sativa in Response to these Viruses
    (EP, 2018) Abd El-Tawab, Rana K; Mokhtar, Sara A.; Bayoumi, Faten S.; El-Senousy, Waled M
    This study aimed to investigate the frequency of enteroviruses in irrigation water of Egyptian rural and urban areas and also studying the effect of ethanolic extract of Nigella sativa on these viruses in vitro. 23 samples were collected from irrigation water sites which irrigate freshly eaten crops on El-Giza and El-Menofya Governorates from March 2017 to May 2017; fourteen samples from five rural sites in El-Menofya which no sanitation systems serve these regions and nine samples from three urban sites in El-Giza served by sanitation systems were investigated. From these samples, Adenoviruses were the highly detected (39.1%) followed by rota viruses (26.1%) and then noroviruses (8.7%). Presence of sanitation systems may affect the frequency of enteric viruses in irrigation water. Rotaviruses were the most frequent in the diarrheal samples collected from the same areas of irrigation water samples followed by adenoviruses and finally noroviruses. Considerable reduction of genome copies and infectious units of both rotavirus Wa strain and adenovirus type 7 was observed by treatment with ethanolic extract of Nigella Sativa in vitro