In Egypt, orange juice industries generate huge amount of waste peel that could be a source of raw materials with high
value and economic return. Here, we explored a better model for waste management of citrus processing waste in Egypt by
developing an ecofriendly method for preparation of value added materials. A high grade pectin (HGP) was obtained from
the crude acidic water extract of the peel after passing through Diaion HP20 column. The HGP showed potent antidiabetic
activity at lower dose than those reported in literature. It possessed significant effect on blood glucose (BG) level, as well as
parameters relevant to liver and kidney functions in streptozotocin (STZ) induced diabetic rats. On the other hand, the
essential oil (EO) prepared by cold press showed the highest yield (0.72% w/w) and it is the most applicable method of
isolate orange oil on pilot scale. EO showed significant antimicrobial activity against the tested food borne pathogens. In
conclusion, high value materials — HGP and EO were prepared on pilot scale from the waste orange peel. While the HGP
can be included in food supplement for diabetic patients, EO can be used as a natural food preservative.
