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Browsing by Subject "Young Adult"

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C(-260)T polymorphism in CD14 receptor gene of Egyptians with acute myocardial infarction

Hashad I.M.; Hossni N.M.; Abdel Rahman M.F.; Shehata M.; Shaban G.; Gad M.Z. (Bentham Science Publishers B.V., 2018)

Background: Despite the significance of the traditional risk factors, recently published studies have suggested that inflammatory processes and variations in the genetics of the inflammatory system may participate in the ...
Can zinc levels predict response to pegylated-interferon and ribavirin therapy in hepatitis c genotype 4 infected Egyptian patients?

Mohamed A.A.; Abbassi M.M.; Hamed W.A.; Ezzel-Arab M.A.; Aref A.M. (Universa Press, 2014)

Background and Aims: Zinc has been found to be low in chronic hepatitis patients. Its level was correlated with response to Interferon/ribavirin therapy in patients infected with hepatitis C genotype 1. In Egypt, inexpensive ...
Cathepsin D expression in chronic plaque psoriasis: An immunohistochemical study

Abdou A.G.; Maraee A.H.; Shoeib M.A.E.; Elsammie A.A.A.; Elnaidany N.F. (2011)

Cathepsins are lysosomal cysteine proteases, which are involved in a variety of physiologic processes such as proenzyme activation, antigen presentation, tissue remodeling, bone matrix resorption, and pathologic processes ...
Clinical and laboratory profile of urinary tract infections associated with extended spectrum-lactamase producing Escherichia coli and Klebsiella pneumoniae

Al Yousef S.A.; Younis S.; Farrag E.; Moussa H.S.; Bayoumi F.S.; Ali A.M. (International Journal of Green EconomicsAssociation of Clinical Scientists, 2016)

Background. Urinary tract infection (UTI) is mainly due to invasion of the urethra, bladder or kidneys by pathogens. The emergence of extended spectrum �-lactamases (ESBL) is responsible for frequently observed empirical ...
Diagnostic and prognostic role of galectin 3 expression in cutaneous melanoma

Abdou A.G.; Hammam M.A.; Farargy S.E.; Farag A.G.A.; El Shafey E.N.; Farouk S.; Elnaidany N.F. (2010)

Many of the histopathologic criteria used to diagnose melanoma overlap with atypical but otherwise benign naevi such as dysplastic or Spitz naevi. Galectin-3 is a member of the galectin gene family and is expressed at ...
Differential expression of RAGE, EGFR and Ki-67 in primary tumors and lymph node deposits of breast carcinoma

Aboushousha T.; Hammam O.; Safwat G.; Eesa A.; Ahmed S.; Esmat M.E.; Helmy A.H. (Wiley-VCH VerlagAsian Pacific Organization for Cancer Prevention, 2018)

Background: Breast cancer is a complex disease that results from the inheritance of a number of susceptible genes. Intensive search wok was conducted world-wide on molecular bases of breast cancer in order to achieve the ...
Evaluation of genexpert MTB/RIF assay for direct diagnosis of pulmonary tuberculosis

Moussa H.S.; Bayoumi F.S.; Ali A.M. (Saudi Arabian Armed Forces Hospital, 2016)

Objectives: To evaluate the performance of GeneXpert MTB/RIF assay for direct diagnosis of pulmonary tuberculosis (PTB). Methods: This is a cross-sectional study conducted between October 2013 and February 2016 at Abbassaia ...
Evaluation of the effect and mechanism of action of local phenytoin in treatment of vitiligo

Abdou A.G.; Abdelwahed Gaber M.; Elnaidany N.F.; Elnagar A. (Taylor and Francis Inc., 2017)

There are many theories explaining vitiligo such as genetic, autoimmune, neural, free radicals, biochemical, intrinsic defect, melanocytorrhagy, and convergent theories. Phenytoin is a widely used anticonvulsant, which is ...
First report of NDM-1-producing Pseudomonas aeruginosa in Egypt

Zafer M.M.; Amin M.; ElMahallawy H.; Ashour M.S.E.D.; AlAgamy M. (Elsevier, 2014)

This work reports the occurrence of New Delhi metallo-beta-lactamase 1 (NDM-1) in metallo-beta-lactamase-producing Pseudomonas aeruginosa in Egypt for the first time, and the presence of more than one blaMBL gene in ...
Macrophage migration inhibitory factor as an incriminating agent in vitiligo

Farag A.G.A.; Habib M.S.; Kamh M.E.; Hammam M.A.; Elnaidany N.F. (Sociedade Brasileira de Dermatologia, 2018)

Background: Vitiligo is an autoimmune skin disorder in which the loss of melanocytes is mainly attributed to defective autoimmune mechanisms and, lately, there has been more emphasis on autoinflammatory mediators. Among ...
Mucosal co-delivery of ketorolac and lidocaine using polymeric wafers for dental application

El-Feky G.S.; Abdulmaguid R.F.; Zayed G.M.; Kamel R. (Taylor and Francis Ltd, 2018)

The current study aimed to investigate the effectiveness of a developed sodium alginate and polyvinyl-pyrrolidone K-25 (PVP K-25) polymeric wafer for the co-delivery of ketorolac and lidocaine to soft tissues for healing ...
Osteopontin expression in chronic plaque psoriasis: An association with the severity of disease

Abdou A.G.; El Farargy S.; Seleit I.; Antar A.G.; Elhefny M.; Elnaidany N.F. (2012)

Objective: To explore the possible role of osteopontin (OPN) in chronic plaque psoriasis and understand the role of inflammation in psoriasis. STUDY DESIGN: We investigated 36 patients with chronic plaque psoriasis using ...
Pharmaceutical and Pharmacokinetic Evaluation of a Novel Fast Dissolving Film Formulation of Flupentixol Dihydrochloride

Abdelbary A.; Bendas E.R.; Ramadan A.A.; Mostafa D.A. (Springer New York LLC, 2014)

The objective of the present study was to develop fast dissolving oral film of the antipsychotic drug, flupentixol dihydrochloride, to enhance its bioavailability, optimize its therapeutic effect when used to treat depression ...
The prognostic significance of the long non-coding RNAs “CCAT1, PVT1” in t(8;21) associated Acute Myeloid Leukemia

El-Khazragy N.; Elayat W.; Matbouly S.; Seliman S.; Sami A.; Safwat G.; Diab A. (Elsevier B.V., 2019)

Long non-coding RNA (LncRNA) is recently linked to various types of cancers, CCAT and PVT1 are two LncRNAs linked to t(8;21) associated Acute Myeloid Leukemia, the interplay between CCAT, PVT1 and the MYC proto-oncogene ...
Regional versus IV analgesics in labor

Sweed N.; Sabry N.; Azab T.; Nour S. (2011)

Aim. The aim of this study was to compare combined spinal epidural (CSE), epidural (E) and IV pethidine analgesia and their effects on the mother, fetus, newborn and the labor course. Methods. This is a prospective parallel ...
The role of antifungal therapy in the prevention of recurrent allergic fungal rhinosinusitis after functional endoscopic sinus surgery: A randomized, controlled study

Khalil Y.; Tharwat A.; Abdou A.G.; Essa E.; Essawy A.H.; Elnakib O.; Elnaidany N.F. (2011)

Allergic fungal rhinosinusitis (AFRS) is the most common form of fungal sinus disease. Its recurrence rate is high despite numerous strategies to prevent it. We conducted a study to assess the effect of systemic and topical ...
The role of hepatic progenitor cells in predicting response to therapy in Egyptian patients with chronic hepatitis C, genotype 4

Helal T.E.A.; Radwan N.A.; Mahmoud H.A.; Zaki A.M.E.; Ahmed N.S.; Wahib A.A.A.; Aref A.M. (Makerere University, Medical School, 2019)

Background: Interferon therapy is used as a line of treatment of chronic hepatitis C virus (HCV) in several areas of the world including Egypt. Objective: Our aim was to investigate the value of hepatic progenitor cells ...
The role of IL-28, IFN-?, and TNF-? in predicting response to pegylated interferon/ribavirin in chronic HCV patients

Abdou A.G.; Asaad N.Y.; Ehsan N.; Eltahmody M.; El-Sabaawy M.M.; Elkholy S.; Elnaidany N.F. (Blackwell Munksgaard, 2015)

The primary goal of HCV therapy is to achieve a sustained virological response (SVR). Many host and viral factors influence the treatment response. Cytokines play an important role in the defense against viral infections, ...
The role of microRNA-31 and microRNA-21 as regulatory biomarkers in the activation of T lymphocytes of Egyptian lupus patients

Amr K.S.; Bayoumi F.S.; Elgengehy F.T.; Abdallah S.O.; Ahmed H.H.; Eissa E. (Springer Verlag, 2016)

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by familial aggregation and genetic predisposition. MicroRNAs (MiRNAs) serve as critical biomarkers in lupus patients because of their aberrant ...
Up-regulation of Notch-1 in psoriasis: An immunohistochemical study

Abdou A.G.; Maraee A.H.; Sharaf A.; Elnaidany N.F. (2012)

The Notch pathway plays a key role in differentiation, proliferation, and influencing cell fate decision in multiple organisms and tissues including the epidermis and its appendages. The role of Notch-1 in psoriasis has ...

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